Effect of different sources of selenium on performance and characteristics of immune system of broiler chickens

Abstract

Non-ruminants Full-length research article Effect of different sources of selenium on performance and characteristics of immune system of broiler chickens ABSTRACT-An experiment was conducted based on a completely randomized design with 500 Ross 308 broiler chickens to investigate the effect of three different sources of selenium on performance and characteristics of immune system. Chickens were arranged in 10 treatments and five repetitions (10 chickens for each repetition). Ten treatments of experimental diet were considered in the study, including a basal diet (control); 0.5, 0.8, and 1.2 mg nano-selenium + basal diet (three treatments); 0.5, 0.8, 1.2 mg selenomethionine + basal diet; and 65, 80, and 100 mg vitamin E + selenium + basal diet. Findings suggested that adding selenomethionine (1.2 mg) to the basal diet resulted in a significant effect on feed conversion ratio and weight of broilers. In fact, weight and bursa of Fabricius were significantly under influence of the diets containing nano-selenium. Moreover, a significant difference was observed in the antibodies produced against Newcastle and influenza as well as the total immunoglobin and IgG produced against sheep red blood cell at two stages in the group treated with nanoselenium. Finally, results indicated that nano-selenium can better improve performance and immune system of broilers compared with diets containing selenomethionine and vitamin E.

Comparative assessment of sodium selenite, selenised yeast and nanosized elemental selenium on performance response, immunity and antioxidative function of broiler chickens

“…Our results are in good comparison with the findings of other researchers (Niu et al 2009;Habibian et al 2014;Boostani et al 2015;Safdari-Rostamabad et al 2017;Bakhshalinejad et al 2018), that showed higher antibody responses to SRBC following dietary intake of SY, SM or SN. Also confirming our findings, Shabani et al (2019) found that SN was more effective in enhancing the antibody response against SRBC than SY, and Shojadoost et al (2020) showed that SY had a higher ability to improve titres against low pathogenicity AIV compared with SS. In contrast, Bakhshalinejad et al (2018) reported higher antibody titre increases to SRBC with supplementary SY versus the same level (0.1 or 0.4 mg/kg diet) of nanosized Se, which might originate from their larger size (50 to 70 nm) of nanoparticles.…”

“…Se deficiency influences unfavourably immune cell development and differentiation in both innate and acquired immune defences, as manifested with atrophy of lymphoid tissues, decreased number of T and B lymphocytes, and impaired immune functions including lymphocyte proliferation, pro-inflammatory cytokine secretions, antibody responses, macrophage phagocytic activity and specific functions of heterophils (Liu et al 2016;Yang et al 2016;Pan et al 2018;Yiming et al 2020). However, the impact of Se supplementation on the immune system varies under different environments (Habibian et al 2014;Rama Rao et al 2016) and is highly influenced by the level and source of dietary Se (Boostani et al 2015;Wang et al 2016;Shabani et al 2019;Shojadoost et al 2020).…”

Dietary supplementation of nano-selenium improves reproductive performance, sexual behavior and deposition of selenium in the testis and ovary of Japanese quail

“…Another study suggested that nano-Se supplementation did not affect the body weight gain of broiler chickens [ 39 – 41 ]. However, in quails, 0.25-ppm nano-Se improved the final body weight, whereas higher inorganic Se negatively affected performance [ 42 ].…”

Influence of bacterial organic selenium on blood parameters, immune response, selenium retention and intestinal morphology of broiler chickens

“…Selenium supplementation in different sources significantly improved white blood cells (WBCs) and red blood cells (RBCs) in broiler chickens compared to sodium selenite. However among the different Se sources, elemental Se had the better effect on the immunity response [9]. Moreover, it has been reported that Se deficient diets lead to a cellular and humoral immunity damages.…”