Angiogenesis of Extracted Tooth Wound on Wistar Rats After Application of Okra (Abelmoschus esculentus) Gel Extract

Luthfi, Muhammad; Juliastuti, Wisnu Setyari; Risky, Yuniar Aliyah

doi:10.1590/pboci.2020.037

Cited by 5 publications

(3 citation statements)

References 16 publications

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“…The application of the treatment was carried out every day. 4,24 Wistar rats were euthanized on the 5th, 7th, and 14th days and then the tissue was cut to make histological preparations with haematoxylin eosin (HE) staining. The number of osteoblasts was counted using an optilab microscope in 3 fields of view with 400x magnification.…”

Section: Methodsmentioning

confidence: 99%

The Effect of Ramania Leaves Extract Gel (Bouea macrophylla Griff) on the Number of Osteoblast (in vivo Study of Post Extraction in Wistar Rats (Rattus norvegicus))

Taufiqurrahman,

Gupita,

Oktiani

et al. 2024

Pharmacogn J.

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Ramania leaves extract contains secondary metabolite compounds such as flavonoids, steroids, phenols and terpenoids which can be used as an alternative medicine for socket wound healing. Flavonoids have anti-inflammatory and antioxidant properties that can accelerate wound healing and can stimulate the formation of osteoblasts. Analyzing the differences in the number of osteoblasts in the negative control group, positive control given aloe vera gel 15% and ramania leaf extract gel 15% on day 5, 7 and 14. This study used true experimental design with posttest-only control design, using 27 rats divide into 3 groups. The experimental animals were sacrificed on days 5, 7 and 14 for histopathological observations. Two-Way ANOVA test results obtained p value = 0.013 <0.05, which indicates that there is a significant difference between the use of 15% ramania leaf extract gel 15% and the number of osteoblasts on days 5, 7 and 14. Bonferroni's Post Hoc test showed a difference. The number of osteoblasts was significant among the negative control group with ramania leaf extract gel 15%. Ramania leaf extract gel 15% was proven to be able to increase the number of osteoblasts and has the potential as an alternative medicine for socket healing after tooth extraction.

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Section: Methodsmentioning

confidence: 99%

The Effect of Ramania Leaves Extract Gel (Bouea macrophylla Griff) on the Number of Osteoblast (in vivo Study of Post Extraction in Wistar Rats (Rattus norvegicus))

Taufiqurrahman,

Gupita,

Oktiani

et al. 2024

Pharmacogn J.

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“…Increases angiogenesis during the wound healing process in oral cavity Luthfi M, 2020 [269] Amla activation markers [217] [250]- [258], Scrophularia striata decreases the number of lymphocytes and enhanced the number of fibroblasts also the maturaty of collagen fibers and showed an additional angiogenic action [259] [260] [261] [262] [263]. Alternanthera sessilis has showed an effect on cell migration of human dermal fibroblasts and keratinocytes [264] [265] [266].…”

Section: Induces Granulation Tissue Formation In the Remodeling Phasementioning

confidence: 99%

“…Euphorbiaceae species accelerates the rate of wound healing process and showed 100% wound contraction [267], Abelmoschus esculentus okra & Amla (emblic myrobalan) showed benefic effects on gingivitis, antibacterial effect and stabilizing collagen [268] [269].…”

Section: Induces Granulation Tissue Formation In the Remodeling Phasementioning

confidence: 99%

An Overview of the Use of Medicinal Plants in Regenerative Dentistry

Dhoum¹,

Ibenmoussa²,

Sidqui³

2023

OJST

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Aim: The oral cavity has the particularity to host multiple hard and soft tissues, in this paper, we will discuss the current therapies that lead to cell differentiation by regenerative therapies and the future alternatives proposed by medicinal plants and all the regenerative potential of these different tissues. Material and Methods: A detailed review of the literature through the various search engines: Scopus, PubMed, google scholar, Cochrane, etc., uses the selected keywords to explore the effect of the regenerative potential of several medicinal plants. Results: Through our research, we have proceeded to sort different medicinal plants, according to their repairing and regenerative potential on the different tissues of the oral cavity. Conclusion: Future studies are conceivable to explore the opportunities and potential provided by medicinal plants in the field of regenerative dentistry.

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Plant-based mucilage with healing and anti-inflammatory actions for topical application: A review

Filho

Lira

Sousa

et al. 2021

Food Hydrocolloids for Health

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Angiogenesis of Extracted Tooth Wound on Wistar Rats After Application of Okra (Abelmoschus esculentus) Gel Extract

Cited by 5 publications

References 16 publications

The Effect of Ramania Leaves Extract Gel (Bouea macrophylla Griff) on the Number of Osteoblast (in vivo Study of Post Extraction in Wistar Rats (Rattus norvegicus))

The Effect of Ramania Leaves Extract Gel (Bouea macrophylla Griff) on the Number of Osteoblast (in vivo Study of Post Extraction in Wistar Rats (Rattus norvegicus))

An Overview of the Use of Medicinal Plants in Regenerative Dentistry

Plant-based mucilage with healing and anti-inflammatory actions for topical application: A review

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