Vitamin D alleviates skeletal muscle loss and insulin resistance by inducing vitamin D receptor expression and regulating the AMPK/SIRT1 signaling pathway in mice

Li, Aijuan; Shen, Pengcheng; Liu, Sijia; Wang, Jiao; Zeng, Jingru; Du, Chunping

doi:10.1590/fst.47921

Cited by 6 publications

(6 citation statements)

References 29 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vitamins are essential nutrients that perform specific and vital functions for health (Zang et al, 2011). Vitamin D can be converted into an active form after ingestion from animal foods (Li et al, 2022). It regulates calcium absorption, serum calcium and phosphorus level to maintain bone structure (Devkate et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Determination of vitamin D level in chicken eggs from conventional and free range systems

et al. 2023

View full text Add to dashboard Cite

This study aimed to investigate the vitamin D levels and some quality features of eggs. A total of 150 eggs (75 conventional and 75 free-range) were selected for the study. The levels of 25-OH vitamin D were determined by liquid chromatography with tandem mass spectrometry (LC-MS/MS) in egg yolks. Furthermore, we evaluated the weights of egg, yolk, albumen, and yolk color as well as shape index, shell thickness, and percentages of albumen, yolk, and shell. The 25-OH vitamin D levels were significantly higher (P < 0.01) in the conventional than in the free-range eggs. Furthermore, the weights of egg, albumen, yolk, percentage of yolk and yolk color were significantly higher (P < 0.01) in the conventional than in the free-range eggs. However, the shape index, percentage of albumen, percentage of shell and shell thickness were significantly higher (P < 0.01) in the freerange than the conventional eggs. It can be concluded that vitamin D levels in eggs can be related to yolk color. However, egg quality characteristics can also be influenced by various environmental factors.

show abstract

Section: Discussionmentioning

confidence: 99%

Determination of vitamin D level in chicken eggs from conventional and free range systems

et al. 2023

View full text Add to dashboard Cite

show abstract

“…An efficient method for improving muscle growth and strength as well as overall physical performance in older persons is the combination of resistance training and post-exercise protein supplementation (Khor et al, 2022;Velasco et al, 2022). Vitamin D intake is critical for older adults because of its widely recognized links to bone health, muscle strength and function (Li et al, 2022;Prokopidis et al, 2022b;Wang et al, 2022). The predominant form of vitamin D found in circulation is 25-hydroxyvitamin D (25(OH)D) (Bollen et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

The effect of dietary supplements on frailty in older persons: a meta-analysis and systematic review of randomized controlled trials

Yan

WANG³

et al. 2022

Food Sci. Technol

View full text Add to dashboard Cite

Frailty is a geriatric syndrome that predicts the onset of disability, morbidity and mortality in elderly people; it is a state of pre-disability and is reversible. This review aimed to assess the impact of dietary supplementation interventions in frail older adults. A systematic search of PubMed, Web of Science, Embase, and the Cochrane Library databases was performed to collect randomized controlled trials of dietary supplements for the treatment of frailty in the elderly published before March 2022. The frailty score, muscle mass, muscle strength and physical performance of the frail elderly were extracted for analysis. Metaanalysis was performed using Review Manager Version 5.4 and Stata version 15.0. Totally, 18 studies met the inclusion criteria, with 1204 participants (603 experiment group vs. 601 control group). Compared to control group, multi-nutrient nutrition intervention can significantly improve the frailty score of the elderly (MD = -0.19, 95% CI: -0.38 to -0.01, P = 0.04, I2 = 0). Protein supplementation intervention significantly improved body weight (MD = 4.86, 95% CI: 1.21 to 8.52, P = 0.009), muscle mass [lean mass (MD = 2.73, 95% CI:1.26 to 4.20, P = 0.0003)], muscle strength (MD = 1.90, 95% CI: 0.68 to 3.12, P = 0.002), and physical performance [chair stand test (MD = -2.15, 95% CI: -3.21 to -1.10, P < 0.0001)] in frail older adults compared to control. This meta-analysis and systematic review suggests that dietary supplements interventions positively influence in older people with frailty.

show abstract

“…The damage produced by sepsis to several organs, including the liver, kidney, and lung, is reduced when SIRT1 is activated because it reduces apoptosis, oxidation, and inflammatory ions (Li et al, 2022;Wang et al, 2022b). Numerous neurodegenerative disorders, ischemia damage, and traumatic brain injury have all been linked to SIRT1's neuroprotective effects (Nadtochiy et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

Activation of SIRT1 signaling pathway by clove improves cognitive dysfunction in septic mice

et al. 2022

View full text Add to dashboard Cite

Clove is a kind of food spice, which can be used as food flavoring additive. In this work, we looked at clove's impact and underlying mechanism on cognitive impairment in infected mice. By using the open field test, Morris water maze, ELISA technique, kit method, and qPCR method, the biochemical and molecular biological indices of mice were identified. Clove component composition was established using HPLC. The findings demonstrated that clove might enhance mouse survival rates in comparison to the model group and could also lengthen driving distances, standing and combing periods, target quadrant duration, and crossing periods. In the hippocampus of infected mice, clove can lower levels of TNF-α, IL-6, IL-1β, and MDA while increasing SOD and CAT activity. In the hippocampus of infected animals, clove additionally increased the mRNA expression of SIRT1 and FOXO1 and decreased the mRNA expression of NF-B and p53. Animal studies revealed that clove's impact was comparable to dexamethasone in that it might help septic mice with cognitive impairment. The analysis revealed that rutin, isoquercitrin, ferulic acid, dihydroquercetin, and quercitrin were all present in clove. It is clear that clove can help septic mice with cognitive impairment by triggering SIRT1 through its active components.

show abstract

Vitamin D alleviates skeletal muscle loss and insulin resistance by inducing vitamin D receptor expression and regulating the AMPK/SIRT1 signaling pathway in mice

Cited by 6 publications

References 29 publications

Determination of vitamin D level in chicken eggs from conventional and free range systems

Determination of vitamin D level in chicken eggs from conventional and free range systems

The effect of dietary supplements on frailty in older persons: a meta-analysis and systematic review of randomized controlled trials

Activation of SIRT1 signaling pathway by clove improves cognitive dysfunction in septic mice

Contact Info

Product

Resources

About