Nanotechnology is one of the newest and most interesting areas of recent years. It offers innovations in diagnosis and treatment with the integration of limited size nanoparticles into larger living systems. It was found application in the field of microbiology, vaccine production, wound healing, tissue regeneration, and genetic, especially in pharmacology. It was significantly increased in the life quality of patients compared with traditional methods due to a number of superiorities such as demonstrated tumor specificity especially in the field of oncology, pass the blood brain barrier in neurodegenerative diseases and offer non-invasive alternatives in diabetes. However, there are also some risks of systemic, genetic and cytotoxic. With this study, it was aimed to inform about the status of nanotechnology in the field of pharmacology, advantages and drug carrier systems.

This study aimed to investigate the vitamin D levels and some quality features of eggs. A total of 150 eggs (75 conventional and 75 free-range) were selected for the study. The levels of 25-OH vitamin D were determined by liquid chromatography with tandem mass spectrometry (LC-MS/MS) in egg yolks. Furthermore, we evaluated the weights of egg, yolk, albumen, and yolk color as well as shape index, shell thickness, and percentages of albumen, yolk, and shell. The 25-OH vitamin D levels were significantly higher (P < 0.01) in the conventional than in the free-range eggs. Furthermore, the weights of egg, albumen, yolk, percentage of yolk and yolk color were significantly higher (P < 0.01) in the conventional than in the free-range eggs. However, the shape index, percentage of albumen, percentage of shell and shell thickness were significantly higher (P < 0.01) in the freerange than the conventional eggs. It can be concluded that vitamin D levels in eggs can be related to yolk color. However, egg quality characteristics can also be influenced by various environmental factors.

Purpose: This study was conducted to investigate the level of blood and hair mercury transition in rabbits depending on the number of amalgam filled teeth in the mouth. Material and Methods: A total of 18 male rabbits from New Zealand were used in the study.  The rabbits were separated into three groups in this study. The first group was named as control group, the second group was named as dichotomous filled group,   and the third group was named as quadruple amalgam filled group. Blood samples were collected from filler animals before the filling, at 24 hour, at the first week and month and also hair samples were taken before the filling and at the first month. The transfer of mercury, taken by the blood and feather samples of rabbits in the study, was made with the hydride system in the absorption spectrophometer. Results: The data’s, obtained from the study, were evaluated by using the SPSS 21 package program. Compared by the control group at the 24th hour, any statically difference wasn’t seen between dichotomous and quadruple amalgam filling groups in terms of blood mercury level. (P>0.05). However, the level of blood mercury, one week and one month later was significantly higher than the control group.(P<0.05) In the all periods, the level of blood mercury was found similar between dichotomous and quadruple amalgam filling groups (P>0.05). Conclusions: Mercury couldn’t be detected in hair samples. As a result, it was revealed that amalgam filling affects the blood mercury level.   How to cite this article: Yerebasan Ü, Servi K, Ataş O, Doğan MS. The determination of mercury levels in the blood and hair of rabbits with amalgam fillings. Int Dent Res 2020;10(1):12-16. https://doi.org/10.5577/intdentres.2020.vol10.no1.3   Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

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