Synergistic effects of unripe raspberry extracts (Rubus chingii) and antibiotics against three bacteria

Jiang, Huichuan; Yang, Jing; Fan, Yujiang; Liu, Yongping

doi:10.1590/fst.04020

Cited by 4 publications

(2 citation statements)

References 30 publications

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“…Free radicals are electrophiles that damage cellular components and destroy proteins, lipids, and, most importantly, nucleic acids, and cause oxidative stress (Jiang et al, 2020;Kornobis, 2021). Increased oxidative stress in people with diabetes leads to a wide range of diseases such as retinopathy, nephropathy, neuropathy, cardiovascular disease, and sexual and hormonal disorders.…”

Section: Introductionmentioning

confidence: 99%

Determination of the antioxidant and mineral contents of raspberry varieties

et al. 2022

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Humans maintain their health by consuming a variety of vegetables and fruits that contain antioxidants, both enzymatic and no enzymatic. Raspberry is one of the most diverse genus of true dicotyledonous plants, which includes 12 subspecies and about 429 species. Raspberry fruit is rich in antioxidant compounds, especially polyphenols. Two species of raspberry were studied to determine the amount of antioxidants and phenolic and flavonoid compounds in their fruits at three different stages of fruit ripening immature, semi-ripe and mature. Natural samples of Rubus idaeus and Rubus strigosus were collected. In this study, the fruit extracts of two species were stored at -23 °C for about six months. Free radical cleansing and Ferric reducing antioxidant power methods were used to determine the antioxidant activities of the extracts. The antioxidant activity of both methods revealed a higher mean value in extracts from fully matured fruits compared with immature and semi-ripe fruits. The results showed that the antioxidant activity of Rubus strigosus is 9%, 10%, and 8% higher than Rubus idaeus in the stages of immature, semi-ripe, and full maturity, respectively.

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Section: Introductionmentioning

confidence: 99%

Determination of the antioxidant and mineral contents of raspberry varieties

et al. 2022

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“…However, almost all peony leaves (PL), including ornamental and oil peony, are discarded as by-products. The phenolic compounds from different sources may play specific role in health by regulating metabolism and cell proliferation, especially phenolics from by-products improve economic benefits (Jiang et al, 2021. Therefore, a feasible extraction process is being expected to utilize of these non-medicinal PR and abandoned PL.…”

Section: Introductionmentioning

confidence: 99%

Optimization of ultrasound-homogenization combined extraction of phenolics in peony roots and leaves

Wang

et al. 2022

Food Sci. Technol

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Paeonia ostii is the representative of oil-utilized peony, its roots (PR) and leaves (PL) are discarded as by-products, resulting in a waste of resources. The exploration of extraction process of active ingredients from PR/PL is beneficial to the comprehensive utilization. In this work, the optimum process of Ultrasound-Assisted Extraction (UAEo) of total flavonoids content (TFC) from PR and PL was determined by single factor and response surface methodology. The results showed that UAEo was 80 min, 1:5 g/mL, 250 W, 33.83 mg Rutin/g dw for PR and 60 min, 1:10 g/mL, 250 W, 25.85 mg Rutin/g dw for PL. Then, Homogenization-Assisted Extraction (HAE), Homogenization-Ultrasound-Assisted Extraction (HUAEo) and Ultrasound-Homogenization-Assisted Extraction (UHAEo) were further analyzed. The highest PR(PL)-TFC by HUAEo at homogenization 5 min was 49.58 ± 0.25 mg/g with an increase of 46.6% (33.02 ± 0.04 mg/g with an increase of 27.7%). The highest PR/PL-total phenolic content by the HUAEo reached 77.84 ± 0.52 mg/g dw and 146.62 ± 2.77 mg/g dw for homogenization 3 min. However, there was no significant difference between HUAEo and UHAEo. In conclusion, the TFC increased with the extension of HAE time, and the combined extraction was higher yield than the single extraction.

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Correlation between Antimicrobial Activity Values and Total Phenolic Content/Antioxidant Activity in Rubus idaeus L.

Ispiryan,

Atkociuniene,

Makstutiene

et al. 2024

Plants

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Plant by-products, which are discarded into the environment, are rich in valuable compounds. The aim of this research was to determine the antibacterial activity of Rubus idaeus L. morphological parts and its correlation with total phenolic content and antioxidant activity. The authors also aimed to evaluate the plant’s potential as added-value products. New aspects were revealed for further use and for making novel and natural products. The study’s results indicated that raspberry leaves, inflorescences, and fruits could effectively combat three Gram-positive bacteria. According to the findings, among the various plant parts, root and seed extracts had the lowest antibacterial activity. Data revealed moderate, weak, or very weak correlation between the antimicrobial activity and phenolic content parameters. These findings underscore the viability of substituting synthetic antimicrobials with natural alternatives. The present study is significant for preparing novel products as antibacterials by appropriate and optimized processing using all raspberry morphological parts, and the research results show promising prospects for future purposeful utilisation of nature-based products. Raspberry plant parts can find applications in emerging fields that generate economic and environmental value.

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Synergistic effects of unripe raspberry extracts (Rubus chingii) and antibiotics against three bacteria

Cited by 4 publications

References 30 publications

Determination of the antioxidant and mineral contents of raspberry varieties

Determination of the antioxidant and mineral contents of raspberry varieties

Optimization of ultrasound-homogenization combined extraction of phenolics in peony roots and leaves

Correlation between Antimicrobial Activity Values and Total Phenolic Content/Antioxidant Activity in Rubus idaeus L.

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