S100 negative granular cell tumor of the oral cavity: dermoscopy and surgical approach

Mejía, Hernán; Rubiano, María Fernanda Ordóñez; Osorio, Victoria Lucia Dávila; Gonzalez, Maria

doi:10.1590/abd1806-4841.20197442

Cited by 8 publications

(10 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GCT is uncommon benign neoplasm, most commonly located within the head and neck area, including oral mucosa and tongue, which probably derives from Schwann cells or their precursors 19,20 . Dermoscopy of GCT of the tongue showed central white‐yellowish structureless areas and peripheral polymorphic vessels 21 …”

Section: Resultsmentioning

confidence: 99%

“…Venous lake L purple/red/blue structureless pattern or globules/clods; white structures case control study (IV) 14 [12] Venous lake OM red and blue lacunae; whitish veil case report (V) 1 [13] Pyogenic granuloma L white rail lines; reddish homogenous background; polymorphous vessels case report (V) 1 [14] Pyogenic granuloma L white collarette; white lines; reddish homogenous areas; ulceration, hemorrhagic crusts case report (V) 1 [15] Angiokeratoma circumscriptum T red-bluish lacunas; whitish veil; milky-red areas case report (V) 1 [16] Benign proliferations/cysts Mucocele OM Type 1: purplish color; branching vessels; t ype 2: erythema; hyperkeratotic white material; unclear hairpin vessels; type 3: erythema; yellow areas; marked hairpin vessels case series (IV) 21 [17] Mucocele OM white structureless areas; linear and branched vessels case report (V) 1 [18] Granular cell tumor OM polymorphous, peripherally arranged vessels; white/ yellowish background case report (V) 1 [21] Infectious conditions…”

Section: Vascular Lesionsmentioning

confidence: 99%

“…19,20 Dermoscopy of GCT of the tongue showed central white-yellowish structureless areas and peripheral polymorphic vessels. 21 3.6 | Infectious conditions…”

Section: Granular Cell Tumormentioning

confidence: 99%

See 2 more Smart Citations

Application of mucous membrane dermoscopy (mucoscopy) in diagnostics of benign oral lesions ‐ literature review and preliminary observations from International Dermoscopy Society study

Jha

Vinay

Sławińska

et al. 2020

Dermatologic Therapy

View full text Add to dashboard Cite

Dermoscopy of mucosal surface termed “mucoscopy” is an upcoming offshoot of dermatological imaging. However, the literature on mucoscopy is limited to individual cases and small case series. An organized review or systematic analysis of mucoscopy is lacking. The aim of this review was to summarize the published literature on mucoscopic features of benign conditions affecting the oral mucosa and semi‐mucosa. Additionally, the results of mucoscopic features of diseases, which have not been described before have been presented.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Vascular Lesionsmentioning

confidence: 99%

See 1 more Smart Citation

Application of mucous membrane dermoscopy (mucoscopy) in diagnostics of benign oral lesions ‐ literature review and preliminary observations from International Dermoscopy Society study

Jha

Vinay

Sławińska

et al. 2020

Dermatologic Therapy

View full text Add to dashboard Cite

show abstract

“…[ 29 ] Mucoscopy of GCT of tongue showed central white-yellowish SLAs and peripheral polymorphic vessel in concordance to the reports in literature. [ 29 39 ] The dotted and linear vessels seen in the center of lesion have not been reported before. Molluscum contagiosum of lower lip and mucosal warts observed on dorsum of tongue revealed the mucoscopic findings that were consistent with earlier reports.…”

Section: Discussionmentioning

confidence: 85%

Dermoscopy of oral mucosal lesions: Experience from a tertiary care center in North India and review of literature

Rather

Shah

et al. 2022

Indian Dermatol Online J

View full text Add to dashboard Cite

Background: Patients with mucosal lesions form a significant number of routine outpatients presenting to the dermatology department where diagnostic confirmation using histopathological examination of mucosal biopsy is neither feasible nor warranted in every patient. Objective: To study the dermoscopic features of various mucosal lesions affecting the oral cavity and to assess the reliability of mucoscopy vis-a-vis clinico-laboratory findings. Materials and Methods: An observational, cross-sectional, hospital-based study was conducted over a period of 2 years from March 2019 to February 2021 in the dermatology outpatient department. Patients presenting with oral mucosal lesions, with or without associated cutaneous involvement, were recruited for mucoscopic evaluation after taking an informed written consent. A detailed history and clinical examination, with emphasis on mucocutaneous examination, was performed and findings were recorded on a standard predesigned proforma. Mucoscopy of oral mucosa was carried out using a handheld dermoscope as well as Universal Serial Bus connected video-dermoscope in both nonpolarized and polarized modes. The different mucoscopic features were seen at these sites, compared with each other, analyzed and findings were recorded. A diagnosis was made on the basis of mucoscopic findings and correlated with clinical diagnosis. The data was analyzed using appropriate statistical tests. Results: The mean age of patients was 34.3 years and the mean lesional duration was 68.2 weeks. Oral lichen planus (18.66%) was the most common disorder studied, followed by recurrent apthous stomatitis (16.00%), pigmentary lesions (12.66%), vascular disorders (12.00%), mucocele (5.33%), pemphigus vulgaris (4.66%), and discoid lupus erythematosus (4.66%). Conclusion: Dermoscopy in oral lesions facilitates the visualization of the mucosal surface and provides quick confirmation of diagnosis in various mucosal disorders with advanced diagnostic accuracy. Mucoscopy was found helpful in differentiating the oral ulcers, which are a presenting feature of various serious mucocutaneous disorders. Mucoscopy could be a helpful aid in diagnosing pigmented skin lesions and alleviating the apprehension regarding oral melanoma and serve as a screening tool in case of squamous cell carcinoma lips. Limitations: Confirmatory histopathological analysis and correlation with mucoscopic findings could not be established in our study.

show abstract

“…During the selection process of the systematic review, five publications reporting 6 S100 (−) cases were excluded (Basile & Woo, ; Lerman & Freedman, ; Mejía, Rubiano, Osorio, & González, ; Rawal & Dodson, ; Solomon & Velez, ). These lesions occurred more commonly in men, and the clinical image was different to normal oral GCT, with one lesion developing in the alveolar ridge over a tooth extraction site (Lerman & Freedman, ).…”

Section: Discussionmentioning

confidence: 99%

Oral granular cell tumour: A multicentric study of 56 cases and a systematic review

et al. 2020

View full text Add to dashboard Cite

Objective Granular cell tumour (GCT) is a benign neoplasm that originates from Schwann cells. Within the oral cavity, it usually appears as a lingual nodule and especially amongst female adults. Histologically, GCT shows a proliferation of polygonal cells with eosinophilic granular cytoplasm, which can be associated with a pseudoepitheliomatous hyperplasia (PEH). In this study, we analyse the main clinicopathological data of intraoral GCT and we compare our results with previous studies. Material and Methods We have studied a series of 56 cases of oral GCT in Spain and Brazil, and we have conducted a systematic review in PubMed, Web of Knowledge and Scopus databases, using the keywords: “granular cell tumour” and oral. Results In our series, GCT appeared as an asymptomatic benign tumour that is more frequent in women and in the tongue. PEH was observed in 32% of the lesions. In the review, we collected 282 cases of oral GCT with a similar clinical profile; seven patients had multiple lesions, and 33% of the cases presented PEH. No cases of malignant oral GCT have been described to date. GCT is an uncommon oral benign neoplasm, mainly unique and asymptomatic, derived from Schwann cells. Conclusions Although the etiopathogenesis of this oral tumour is unknown, its characteristics suggest that it could have a reactive nature. Conducting a complete clinicopathological study in all intraoral GCT is fundamental in order to dismiss other entities, including oral carcinoma.

show abstract

S100 negative granular cell tumor of the oral cavity: dermoscopy and surgical approach

Cited by 8 publications

References 8 publications

Application of mucous membrane dermoscopy (mucoscopy) in diagnostics of benign oral lesions ‐ literature review and preliminary observations from International Dermoscopy Society study

Application of mucous membrane dermoscopy (mucoscopy) in diagnostics of benign oral lesions ‐ literature review and preliminary observations from International Dermoscopy Society study

Dermoscopy of oral mucosal lesions: Experience from a tertiary care center in North India and review of literature

Oral granular cell tumour: A multicentric study of 56 cases and a systematic review

Contact Info

Product

Resources

About