Florid cemento-osseous dysplasia and peripheral giant cell granuloma in a patient with neurofibromatosis 1

Abstract

We report a 35-year-old mulatto female patient with neurofibromatosis Type 1 who presented with facial asymmetry. The patient had two lesions: florid cemento-osseous dysplasia associated with peripheral giant cell granuloma. She was referred for surgical treatment of the peripheral giant cell granuloma and the florid cemento-osseous dysplasia was treated conservatively by a multidisciplinary team. So far, no changes have been observed in the patient's clinical status. We observed no recurrence of peripheral giant cell granuloma. To the best of our knowledge, the present case is the first report of a patient with neurofibromatosis Type 1 associated with a giant cell lesion and florid cemento-osseous dysplasia.

Fibrous dysplasia associated with peripheral giant cell granoluma in maxilla in a young patient, a case report of rare hybrid lesion

“…Their case fulfilled the diagnostic criteria for NF1 who had florid cemento-osseous dysplasia associated with PGCG unlike our case with no medical history. 10 …”

“…Their case fulfilled the diagnostic criteria for NF1 who had florid cemento-osseous dysplasia associated with PGCG unlike our case with no medical history. 10 Ramesh et al reported a case of 57 year old female with a hybrid lesion that showed both features of PGCG and POFs in maxilla. Alveolar bone was not involved by the lesion and no calcified bone or cementum was present.…”