Analysis of the histomorphologic profile of invasive cutaneous squamous cell carcinoma from 2002 to 2011 in a pathology laboratory in the region of Campos Gerais, Brazil

Abstract

Squamous cell carcinoma is the second most common type of malignant skin cancer. It is also quite aggressive. The increasing incidence of the disease can be altered given its connection with sun exposure. The aim of this study was to establish the clinical and histomorphological profile of squamous cell carcinoma in the region of Campos Gerais, State of Paraná, Brazil and analyze and compare the features of the disease found in the literature. We conducted a cross-sectional descriptive study in a pathology laboratory with selected invasive cutaneous squamous cell carcinoma reports issued after excisional biopsy from January 2002 to December 2011. We selected 374 cases of head and neck SCC, mean age 71.53 years, with a predominance of male patients, moderate degree of histological differentiation, Clark level IV, and absence of perineural, neural, or angiolymphatic invasions. Our results differ on some points from those found in the literature.

Avaliação global do carcinoma basocelular e espinocelular

“…O estadiamento do carcinoma espinocelular assemelha-se em grande parte ao do carcinoma basocelular, visto que a grande maioria dos diagnósticos é feita através de consultas dermatológicas ou encaminhamento aos serviços de cirurgia plástica. Na avaliação inicial, usualmente utiliza-se o mnemônico ABCDE, classificando-se a lesão como de maior prerrogativa maligna ou benigna através de características como assimetria, bordas, coloração, tamanho e evolução (SOUZA FM, et al, 2017).…”

ESTUDO ANATOMOPATOLÓGICO DOS CASOS DE CÂNCER DE PELE NÃO MELANOMA ATENDIDOS NO HOSPITAL UNIVERSITÁRIO DA UNIVERSIDADE FEDERAL DO PIAUÍ/ Anatomopathological study of non-melanoma skin cancer treated at the University Hospital of the Federal University of Piauí

“…Esse dado condiz com a literatura nacional (SOUZA, et al, 2017). O estudo realizado por de Souza, Montemor Netto e Baroni (2017), no Paraná, com 374 casos de CEC, avaliados entre 2002 e 2011, encontrou 53.5% casos com grau de diferenciação moderado, e o grupo de casos pouco diferenciados correspondeu a menor frequência desse estudo (7,5%) (SOUZA, et al, 2017). O grau de diferenciação histológica é uma variável importante a ser avaliada, associando-se à ocorrência de metástases e óbito.…”

Evaluation of peritumoral inflammatory infiltration and its relationship with different prognostic factors in cutaneous squamous cell carcinoma

“…Cutaneous squamous cell carcinoma (cSCC), as a major type of skin cancer, frequently affecting the head and neck 1 . It accounts for 20% of all non‐melanoma skin cancers worldwide 2 . In the United States alone, about 700 000 new cases of cSCC are estimated to occur each year, and its incidence is on the rise 3 .…”