Tinea faciei on the right eyebrow caused by Trichophyton interdigitale

Zhuang, Kai Wen; Dai, Ya Ling; Ran, Yu Ping; Lama, Jebina; Fan, Yi Ming

doi:10.1590/abd1806-4841.20165270

Cited by 8 publications

(12 citation statements)

References 10 publications

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“…The results of antifungal combinations in humans are reported in Table 3 . There were 25 papers describing 37 single case reports, one paper each describing 36 and 254 patients, respectively, and 3 clinical trials involving a total of 410 patients [ 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 ]. Either paediatric or adult patients were represented.…”

Section: Resultsmentioning

confidence: 99%

Antifungal Combinations in Dermatophytes

Brescini

Fioriti

Morroni

et al. 2021

JoF

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Dermatophytes are the most common cause of fungal infections worldwide, affecting millions of people annually. The emergence of resistance among dermatophytes along with the availability of antifungal susceptibility procedures suitable for testing antifungal agents against this group of fungi make the combinatorial approach particularly interesting to be investigated. Therefore, we reviewed the scientific literature concerning the antifungal combinations against dermatophytes. A literature search on the subject performed in PubMed yielded 68 publications: 37 articles referring to in vitro studies and 31 articles referring to case reports or clinical studies. In vitro studies involved over 400 clinical isolates of dermatophytes (69% Trichophyton spp., 29% Microsporum spp., and 2% Epidermophyton floccosum). Combinations included two antifungal agents or an antifungal agent plus another chemical compound including plant extracts or essential oils, calcineurin inhibitors, peptides, disinfectant agents, and others. In general, drug combinations yielded variable results spanning from synergism to indifference. Antagonism was rarely seen. In over 700 patients with documented dermatophyte infections, an antifungal combination approach could be evaluated. The most frequent combination included a systemic antifungal agent administered orally (i.e., terbinafine, griseofulvin, or azole—mainly itraconazole) plus a topical medication (i.e., azole, terbinafine, ciclopirox, amorolfine) for several weeks. Clinical results indicate that association of antifungal agents is effective, and it might be useful to accelerate the clinical and microbiological healing of a superficial infection. Antifungal combinations in dermatophytes have gained considerable scientific interest over the years and, in consideration of the interesting results available so far, it is desirable to continue the research in this field.

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Section: Resultsmentioning

confidence: 99%

Antifungal Combinations in Dermatophytes

Brescini

Fioriti

Morroni

et al. 2021

JoF

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“…interdigitale from the zoophilic dermatophyte Arthroderma vanbreuseghemii , reports of infections with T . interdigitale and its association with TF in humans is rarely reported [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

First Report of Concomitant Tinea Faciei and Pityriasis Folliculorum: A Dermatomicrobiological Rarity

Vanam

Mohanram

et al. 2018

Cureus

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Tinea faciei (TF) is a common dermatomicrobiological condition caused by dermatophytes involving the skin of the face but not the mustache and beard (Tinea barbae). It poses a diagnostic dilemma with its atypical clinical presentation. Pityriasis folliculorum (PF) is a dermatological condition that results in rosacea-like skin eruptions. It was previously associated with a human ectoparasitic infestation. Demodex mites (Demodex folliculorum) is a group of obligate parasites that live on the skin of mammals. These mites have been associated with various dermatological disorders, clinically termed as demodicosis. Insects have been described as potential vectors that can carry various microorganisms and especially spores of fungi. Hence, infestation by such insects may aggravate the already present skin condition, leading to secondary infections. There has been a change in the trend of dermatophytosis worldwide and infections caused by Trichophyton mentagrophytes var. interdigitale (T. interdigitale) are increasing. Hence, there is an urgent need for a thorough investigation of an infectious etiology among various skin disorders. This is the first report of concomitant Tinea faciei and Pityriasis folliculorum involving facial skin.

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“…Tinea faciei , tinea blepharo-ciliaris , and periocular tinea are ringworm infections of the face, eyelids and eyelashes, and eyelids only, respectively. Caused by Microsporum , Trichophyton , or Epidermophyton species, fungal infections may result in partial unilateral or bilateral hair loss of the eyebrows and eyelashes [ 54 , 55 ]. Trichoscopy of affected eyebrows may show comma hairs (51%), corkscrew hairs (32%), bent hairs (27%), morse code hairs (22%), and zigzag hairs (22%) (Table 1 ) [ 56 ].…”

Section: Etiologies and Trichoscopy Findingsmentioning

confidence: 99%

“…In syphilis , timely treatment with benzathine penicillin G has been reported to result in complete eyebrow regrowth in two case reports [ 51 , 101 ]. Eyebrow and eyelash alopecia due to tinea faciei has been reported to be reversible after treatment with topical and/or oral antifungals in two case reports [ 54 , 102 ].…”

Section: Treatmentsmentioning

confidence: 99%

Eyebrow and Eyelash Alopecia: A Clinical Review

Nguyen

Tosti

2022

Am J Clin Dermatol

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Madarosis is characterized by either complete or partial loss of eyebrow or eyelash hair. Etiologies for madarosis are varied, and accurate diagnosis is the first step in clinical management. Many studies have described findings related to specific causes of madarosis, but few have summarized the collective literature. The purpose of this review is to provide an updated overview on the symptomatology, diagnosis, trichoscopy findings, and treatment of eyebrow and eyelash alopecia.

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Tinea faciei on the right eyebrow caused by Trichophyton interdigitale

Cited by 8 publications

References 10 publications

Antifungal Combinations in Dermatophytes

Antifungal Combinations in Dermatophytes

First Report of Concomitant Tinea Faciei and Pityriasis Folliculorum: A Dermatomicrobiological Rarity

Eyebrow and Eyelash Alopecia: A Clinical Review

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