Primary cutaneous aspergillosis and idiopathic bone marrow aplasia

Abstract

We describe the case of a 9-year-old boy with idiopathic bone marrow aplasia and severe neutropenia, who developed skin ulcers under cardiac monitoring electrodes. The diagnosis of primary cutaneous aspergillosis was made after the second biopsy and culture. Imaging investigation did not reveal internal fungal infection. The child was treated, but did not improve and died 3 months after admission. The report highlights and discusses the preventable risk of aspergillus skin infection in immunocompromised patients.

Anogenital Ulcers: An Unusual Manifestation of Invasive Aspergillosis

“…Invasive fungal diseases represent an important cause of morbidity and mortality, mainly in immunocompromised patients. Aspergillus spp., after Candida albicans , is the second most frequent agent of opportunistic fungal infections, with an increase in its incidence on recent years [1, 2]. It is one of the most ubiquitous fungi but generally does not cause disease in immunocompetent patients [3].…”