Anogenital Ulcers: An Unusual Manifestation of Invasive Aspergillosis

Abstract

Aspergillus spp. is one of the most ubiquitous fungi but generally does not cause disease in immunocompetent patients. It is the second most frequent agent of opportunistic fungal infections, after Candida albicans, with a rise in its incidence on recent years. Invasive fungal diseases represent an important cause of morbidity and mortality. Its origin can be primary, in relation to a cutaneous injury, or secondary, by extension from contiguous tissues, or by hematogenous spread, usually in the context of pulmonary aspergillosis. In this report, we describe the case of an elderly woman with invasive aspergillosis that manifested with anogenital and skin ulcers, with unfavorable outcome, despite intensive therapy and intravenous antifungals.

Antimicrobial Activity of Some Medicinal Herbs to the Treatment of Cutaneous and Mucocutaneous Infections: Preliminary Research

“…Aspergillus spp. is an ubiquitous and opportunistic filamentous fungi but generally does not cause disease in immunocompetent patients and are rarely involved in superficial infections [ 5 , 6 ]. Other fungal agents may be involved in this type of infection, alone or in combination with those described above, as well as the possibility of association with bacteria [ 7 ].…”