Eccrine poroma and porocarcinoma on the same unusual location: report on two cases

Abstract

Eccrine poroma is a benign adnexal tumour of the uppermost portion of the intraepidermal eccrine sweat gland duct and acrosyringium. Eccrine porocarcinoma is the malignant phenotype arising from the intraepidermal portion of the eccrine sweat gland duct epithelium or from pre-existing eccrine poroma. Both commonly occur in the palms or sides of the feet; these areas have a high concentration of eccrine sweat glands. We describe two respective cases of benign and malignant eccrine poroma on the scrotum, which entailed good excisional results.

Porocarcinoma; presentation and management, a meta-analysis of 453 cases

“…These includes; ductal differentiation, nests of basaloid cells, squamoid tumor cells, infiltrative spinal cells, cells of acanthotic epidermis, Borst Judasson appearance, ulcerated epithelial tumor, bowenoid porocarcinoma, nests of small atypical cells, clear-cell, high infilterative pattern and hyperchromatic nuclear [7] , [13] , [26] , [62] , [72] , [103] , [102] . Surgery was the main mode of therapy with adjuvant chemoradiotherapy if metastasis and/or recurrence occurred [50] , [82] , [83] , [84] , [85] , [86] , [87] , [88] , [89] , [90] , [91] , [92] , [93] , [94] , [95] , [96] , [97] , [98] , [99] , [100] , [101] , [102] , [103] , [104] . Metastasis was found in 110 (31%) cases [3] , [10] , [63] , [65] , [68] , [73] , [76] , [86] .…”

A rare case of recurrent eccrine poroma underlying gluteal abscess

“…Histopathological examination is critical to establishing the diagnosis of various rare and recurrent neoplastic lesions including EP due to existence of various clinical and histological differential diagnoses, including benign and malignant lesions, such trichoepithelioma, basal cell carcinoma, hidradenoma papilliferum, follicular (inclusion) cysts, and eccrine porocarcinoma [ [14] , [15] , [16] ].…”

Acquired digital fibrokeratoma: review of its clinical and dermoscopic features and differential diagnosis

“…Eccrine poroma is a benign adnexal tumor of the uppermost portion of the intraepidermal eccrine sweat gland duct. The nonpigmented variant commonly occurs in the palms or sides of the feet . It shares clinical resemblance with ADFK and presents as a skin‐colored or pink papule, plaque, or nodule, but exophytic or ulcerated nodules and hyperkeratotic plaques are also described .…”

“…The nonpigmented variant commonly occurs in the palms or sides of the feet. 39 It shares clinical resemblance with ADFK and presents as a skin-colored or pink papule, plaque, or nodule, but exophytic or ulcerated nodules and hyperkeratotic plaques are also described. 40 Histological examination may show proliferation of uniform cuboid cells with light-colored cytoplasm and evident intercellular bridges that are not seen in ADFK.…”