Recipient site preparation for epidermal graft in stable vitiligo by a special fraise

Abstract

BACKGROUNDThe only approach used in the refractory lesions of stable vitiligo is the surgical supply of melanocytes. Suction Blistering Epidermal Graft is one of the most common and effective techniques. There are multiple modalities, including the motor-driven diamond fraise, for the preparation of recipient sites in suction blistering epidermal graft with different repigmentation rates and complications.OBJECTIVESTo evaluate preparation of recipient site by a motor-driven dental lab finishing carbide bur.METHODSSixty-one stable, depigmented lesions were selected in 14 patients (9 women and 5men), aged 16-29 years, of which 9, 3 and 2 had localized, generalized and segmental vitiligo, respectively. Recipient site was prepared by a motor-driven dental lab finishing carbide bur.RESULTExcellent repigmentation at the recipient site was observed in 53 out of 61 (86.9%) grafted lesions. Postinflammatory hyperpigmentation and perigraft halo were seen in 11 (18%) and 17 (27.9%) patients at the recipient site, respectively.CONCLUSIONUsing a motor-driven dental lab finishing carbide bur to prepare the recipient site of suction blistering epidermal graft technique is reliable and effective, removing only the depigmented epidermis in a simple and safe manner, even on complex-shaped lesions and scar-prone sites.

Updates in Surgical Treatment of Vitiligo

“…Perigraft halo commonly arise with it due to shrinkage of suctioned donor epidermis after removing the sustained negative pressure and due to the inhibitory effects of liquid nitrogen on the melanocytes of peripheral pigmented epidermis [40] . 1.3 Split-thickness skin grafts (STSGs) are carried out by harvesting a thin or ultrathin layer of epidermis from the donor site that is 10% to 20% larger than the recipient site.…”

Treatment of recalcitrant vitiligo by autologous non-cultured and trypsinized melanocyte grafting in the west of Iran

“…Vitiligo is a common pigmenting dermatosis that is associated with problems in several contexts such as education, family, marriage, employment, sex, and social relations. 1 , 2 , 3 , 4 …”

“…There is no definitive cure for vitiligo; therefore, many surgical options such as autologous cultured or non-cultured melanocyte grafting have been developed for the treatment of vitiligo in recent years. 3 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 …”

Successfully treatment of penile vitiligo patches and their sexual dysfunction consequences, by suction blister epidermal grafting

“…In recent years’ surgical interventions such as autologous non-cultured melanocyte grafting (ANCMG) and suction blister epidermal grafting (SBEG) were developed for the treatment of stable vitiligo. 1 , 2 But vitiligo patches on problematic-to-treat areas, such as male genital even with this method may be with poor outcomes. 2 , 3 …”

“… 1 , 2 But vitiligo patches on problematic-to-treat areas, such as male genital even with this method may be with poor outcomes. 2 , 3 …”