Case for diagnosis

Abstract

Majocchi's granuloma is a persistent supurative folliculitis, associated with a deep granulomatous reaction induced by dermatophytes. There are two clinical forms of Majocchi's granuloma: the superficial form that appears in healthy individuals after localized trauma; and the nodular form, which occurs in inmunocompromised patients. We present a case of nodular Majocchi's granuloma on the forearm of an immunocompetent patient. Microbiological culture and examination of a deep aspiration sample identified Trichophyton rubrum. Collecting a deep sample of tissue is essential in achieving a good diagnostic performance.

Majocchi’s granuloma: current perspectives

“…Moreover, shaving the legs or pubic area, sexual contact, and occupation should also be investigated. 7 , 8 , 37 , 38 In this review, four of the patients were thought to have been in contact with an animal, suggesting that animal exposure was a predisposing factor of MG. Three of these patients had been in contact with guinea pigs. 34 , 39 , 40 Guinea pigs are often cryptic carriers, 41 and the clinician should consider the zoophilic characteristics of dermatophytes and whether the patient has a pet or is in frequent contact with animals.…”

Majocchi’s Granuloma (Dermatophytic Granuloma): Updated Therapeutic Options

“…Griseofulvin 0.5-1 g/day is undoubtedly the best therapy for MG since Blanck and Smith first used [3]. Some azoles like systemic ketoconazole at doses of 200 mg/day [61] and itraconazole 200 mg/day or twice daily for periods of 30 to 90 days [15,[62][63][64][65][66] are also recommended, the latter with several different therapeutic schemes (Table 2). According to our experience and the literature research, it is advised to maintain a minimum of 8 weeks in the case of griseofulvin and 6-8 weeks in systemic azoles [13,[67][68][69] and treatment should be continued until all lesions are cleared.…”

Successful Treatment of Refractory Majocchi’s Granuloma with Voriconazole and Review of Published Literature

“…There have been 27 cases of MG in immunocompetent patients reported in English language literature, and details are described in Table 1 ( [1,[6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]). Among the cases, 17 were male (63.0 %) and 10 (37.0 %) were female.…”