Comedo-like openings in melanoma

Santos, Bruno; Ribeiro, Lucia Helena Soares; Ayres, Eloísa Leis; Vilar, Enoí Aparecida Guedes

doi:10.1590/abd1806-4841.20142836

Cited by 5 publications

(4 citation statements)

References 8 publications

(13 reference statements)

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“…A seborrheic wart is another common lesion, which may prove difficult in the differential diagnosis with skin malignant tumours. Dermatoscopic examination is the key diagnostic method here, yet in doubtful cases it is necessary to perform a cutting biopsy and histopathological verification [22–27]. Sonographic images using HFUS of a seborrheic wart have thus far been described in single publications only [6, 8, 12].…”

Section: Resultsmentioning

confidence: 99%

High-frequency ultrasound in the diagnosis of selected non-melanoma skin nodular lesions

Piłat¹,

Borzęcki²,

Jazienicki³

et al. 2019

pdia

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IntroductionUltrasonographic examination is commonly used in an outpatient setting, possibly due to its low cost, low risk for patients and the possibility to obtain real time images. Typically used heads have the frequency ranging from 7.5 to 12 MHz. Higher frequencies ensure higher resolution, yet they are limited by the penetration depth – reaching from several to several tens of millimetres into the skin. High-frequency ultrasonography (HFUS) appears to be a promising method for the detection and differential diagnostics of selected nodular skin lesions.AimThe study aimed at a comparison of the data obtained by using HFUS, histopathological and dermatoscopic images of selected skin lesions to determine their common features.Material and methodsNodular lesions classified as potentially malignant were subjected to clinical, dermatoscopic and high-frequency ultrasonographic examinations. Then the patients were referred for surgical removal with histopathological assessment.ResultsA total of 54 nodular lesions were examined, out of which 34 were diagnosed as non-melanoma. The most common lesions were melanocytic naevi dermatofibroma, nodular basal cell carcinoma and pyogenic granuloma. Other examined lesions included blue naevus, seborrheic wart, xanthogranuloma juvenile and Spits naevus. In all lesions except Spitz naevus, HFUS images corresponded at least with dermatoscopic or histopathology images.ConclusionsHFUS can be used as a supporting diagnostic tool ensuring better pre-operative proceedings. HFUS is a non-invasive, easy and inexpensive screening method for the determination of different skin cancers as it provides valuable information allowing to determine the cutting margins and lesion shape.

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Section: Resultsmentioning

confidence: 99%

High-frequency ultrasound in the diagnosis of selected non-melanoma skin nodular lesions

Piłat¹,

Borzęcki²,

Jazienicki³

et al. 2019

pdia

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“…Literatürde yer alan araştırmalarda melanomlarda gözlenen dermoskopik bulgular arasında atipik pigment ağı, düzensiz nokta/globüller, ışınsal uzantılar, psödopodlar, leke, mavi beyazımsı tül, hipopigmentasyon, beyaz kırmızı alanlar, serpilmiş karabiber görünümü, beyaz skar-benzeri depigmentasyon ve negatif pigment ağı yer almaktadır 3,17,18 . Daha nadir olmakla birlikte multipl milyum benzeri kistler ve komedon benzeri açıklıklar gibi benign lezyonlarda sık gözlenen dermoskopik bulgular da melanomlarda gözlenebilmektedir 19,20 . Lineer düzensiz, noktasal, glomerüler, dallanan ve tirbuşon damarlar ise melanomlarda gözlenebilen atipik damarlar olarak tanımlanmaktadır 21 .…”

Section: Discussionunclassified

“…Bizim olgularımızda da benzer şekilde ince, in situ, mitoz oranı <1, LVİ (-), ülserasyon (-) ve regresyon (-) olan melanomlarda düzensiz nokta/globüllerin daha yüksek oranda gözlendiği belirlenmiş, ancak istatistiksel olarak anlamlılık izlenmemiştir. Dermoskopik olarak daha çok seboreik keratoz gibi benign lezyonlarda tanımlanmış olan komedon benzeri açıklıklar ve multipl milyum benzeri kistler melanomlarda da gözlenebilmektedir 19,20 . Dermoskopide sarı-kahve veya kahve-siyah renkli yuvarlak veya düzensiz şekilli açıklıklar olarak gözlenen komedon benzeri açıklıklar, histopatolojik olarak epidermal invajinasyonlarda ve dilate foliküler açıklıklarda yerleşmiş keratin tıkaçlarını ifade etmektedir.…”

Section: Discussionunclassified

Investigation of the relationship between dermoscopic features and histopathological prognostic indicators in patients with cutaneous melanoma

Özbağçıvan¹,

Lebe²,

Akarsu³

et al. 2015

TURKDERM

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“…The surface is roughly keratotic and the consistency is not friable, unlike SK [39]. The locations vary but are more frequently on the back and limbs [25,29,31]. The lesions develop in elderly, middle-aged, and younger patients alike [30,35].…”

Section: Clinical Featuresmentioning

confidence: 99%

Seborrheic keratosis-like melanoma: a diagnostic challenge

et al. 2021

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This article summarizes the main epidemiologic and diagnostic features of seborrheic keratosis-like (SK-like) melanoma. We performed a review of the current literature. The real and current incidence and prevalence of SK-like melanoma are unknown. Many lesions are misdiagnosed and not excised with histopathologic confirmation, or excised without an appropriate surgical approach due to a benign clinical and dermoscopic appearance. SK-like melanoma presents both melanoma and SK features. SK-like melanoma and SK are often clinically indistinguishable even for experienced dermatologists. Clinically, it develops as a black-dark brown or light slightly elevated, papule, nodule or plaque with rapid growth and a regular or irregular shape. SK-like melanoma presents melanocytic and nonmelanocytic dermoscopic features. Irregular dark-brown dots/globules, a bluegrayish veil, streaks, irregular pigmentation or network and brown lines point to a melanoma diagnosis. Among the nonmelanocytic features, milia-like cysts and comedolike openings have been highlighted. The association of polarized and nonpolarized dermoscopic techniques is more accurate for studying the dermoscopic features of SK-like melanoma. If the dermoscopic features are unclear, further investigations with reflectance confocal microscopy (RCM) or biopsy with histologic examination are essential. SK-like melanoma is a dermatologic challenge. Careful clinical and dermoscopic evaluation favor a correct diagnosis. In unclear cases, it is important to perform a biopsy with histologic examination to confirm the correct diagnosis. Melanoma Res 31: 407-412

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Comedo-like openings in melanoma

Cited by 5 publications

References 8 publications

High-frequency ultrasound in the diagnosis of selected non-melanoma skin nodular lesions

High-frequency ultrasound in the diagnosis of selected non-melanoma skin nodular lesions

Investigation of the relationship between dermoscopic features and histopathological prognostic indicators in patients with cutaneous melanoma

Seborrheic keratosis-like melanoma: a diagnostic challenge

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