Obesidade e fatores de risco cardiometabólicos durante a gravidez

Abstract

The metabolic changes in pregnancy are more significant in obese women, suggesting, as expected, an increased risk of cardiometabolic complications. During their first visit for prenatal care, obese women should be informed about these risks, have their BMI and insulin/glucose ratio calculated along with their lipid profile to identify pregnant women at higher risk for cardiovascular diseases.

Estado Nutricional E Hábitos Alimentares De Gestantes Atendidas Na Atenção Primária De Saúde

“…Semelhantes aos resultados apresentados, outras pesquisas com gestantes mostraram uma frequência elevada de mulheres jovens e prevalência do sobrepeso e obesidade durante o terceiro trimestre gestacional [12][13] .…”

Obstetrical Problems in Pregnant Women With Metabolic Syndrome

“…Известно, что при МС частота развития гестационного сахарного диабета достигает 14 %. Нарушения углеводного обмена во время беременности являются причиной развития макросомии плода и диабетической фетопатии, которые увеличивают риск перинатальной заболеваемости и смертности [12][13][14].…”

Relação do sobrepeso e obesidade materna sobre parâmetros imunológicos, bioquímicos e hormonais do sangue e colostro humano

“…Leptin levels in colostrum during the first weeks after childbirth are negatively associated with baby weight gain at six months (3). This suggests that milk leptin reflects the association between maternal body composition and infant growth and development, playing a critical role in the regulation of appetite and food intake during infancy (38). Part of the protective effects that breastfeeding provides against chronic diseases, especially obesity later in life, have been attributed to leptin (39).…”

“…Part of the protective effects that breastfeeding provides against chronic diseases, especially obesity later in life, have been attributed to leptin (39). Furthermore, other studies report a positive correlation between leptin levels and blood pressure in pregnant women, suggesting increased risk of cardiometabolic complications (38).…”

“…Blood and colostrum adiponectin levels were not correlated, but maternal BMI was positively associated with blood adipokine levels and negatively correlated with colostrum adipokine levels. Other studies report a reduction in serum adiponectin in obese individuals (38,(40)(41)(42), suggesting that fetuses from obese mothers are less able to control inflammation because they exhibit lower circulating levels of these anti-inflammatory adipokines, limiting their optimal growth or even increasing the risk of miscarriage and premature delivery (31). Other studies show a negative correlation between maternal obesity and adiponectin levels, but a positive correlation between BMI and the levels of this hormone in breast milk (14,43).…”