Association between cardiovascular disease and dementia

Suemoto, Cláudia Kimie; Ferretti, Renata E.L.; Grinberg, Lea T.; Oliveira, Kátia C.; Farfel, José Marcelo; Leite, Renata Elaine Paraízo; Nitrini, Ricardo; Pasqualucci, Carlos Augusto

doi:10.1590/s1980-57642009dn30400008

Cited by 6 publications

(5 citation statements)

References 38 publications

(36 reference statements)

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“…Therefore, they did not contribute to the frequency of cardiovascular diseases that we report here. This is supported by the evidence derived from epidemiological studies that have previously linked cardiovascular diseases with dementia 30 and with high mortality 30 days after hip fracture. 29 On the other hand, we observed that the specific absence of heart disease contributed to a better functional state after the fracture.…”

Section: Discussionsupporting

confidence: 53%

Factors Associated with Recovered Functionality After Hip Fracture in Non-Institutionalized Older Adults: A Case-Control Study Nested in a Cohort

Ramírez-García¹,

Torre²,

Reyes³

et al. 2021

CIA

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Purpose To identify factors associated with recovered functionality after a hip fracture in a sample of older adult patients. Patients and Methods Nested case-control study in a cohort. Older adults (60 years or older) with a hip fracture were recruited between May 2017 and October 2018. The Barthel scale was used to measure performance in activities of daily living (ADL). A questionnaire was applied to collect information about demographic, clinic, psychological and social variables, and anthropometric measurements were taken. A logistic regression model was built to analyze various factors related to recovered functionality. Results A total of 346 older adults with a hip fracture were studied (n=173 cases and n=173 controls); 69.4% (n=240) women and 30.6% (n=140) men. Mean age was 79.4 years (±8.7) overall; for cases, 77.4 (±7.9) years and for controls, 81.4 (±9.0). Mean schooling was 6.3 (± 4.3) years. Recovered functionality was associated with normal nutritional status (OR 4.81, 95% CI = 2.54–9.12), absence of heart disease (OR 4.08, 95% CI = 1.48–11.20), self-efficacy for ADL (OR 4.07, 95% CI = 2.15–7.72), absence of depressive symptoms (OR 2.99, 95% CI = 1.69–5.28), prior functionality (OR 2.83, 95% CI = 1.51–5.31), high socioeconomic level (OR 2.41, 95% CI = 1.24–4.65) and transcervical fracture (OR 2.34, 95% CI = 1.05–5.22). Conclusion In older adults who have suffered a hip fracture, clinical, psychological, and demographic characteristics are associated with recovered functionality. These factors should be considered as a priority in the care of older adults who have experienced hip fractures.

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Section: Discussionsupporting

confidence: 53%

Factors Associated with Recovered Functionality After Hip Fracture in Non-Institutionalized Older Adults: A Case-Control Study Nested in a Cohort

Ramírez-García¹,

Torre²,

Reyes³

et al. 2021

CIA

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“…The result of the research showed that cognitive deficit was associated with stroke, physical inactivity, advanced age, and low body mass index (p< 0.05) [14]. Moreover, in patients with dementia, the circle of Willis atherosclerosis was greater than in controls on univariate analysis (p=0.01).…”

Section: Resultsmentioning

confidence: 95%

Risk Factors of Dementia in Elderly at Nursing Home

Fitriana¹,

Rohaedi²,

Sumartini³

et al. 2019

Proceedings of the 3rd International Conference on Sport Science, Health, and Physical Education (ICSSHPE 2018)

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Dementia is a deficit of intellectual function, including language disorders, cognition, personality, visuospatial skills and memories of daily activities. The purposed of this study is to identify the risk factors of dementia in elderly at nursing home. The research design used is correlative descriptive with purposive sampling technique to 58 elderly dementia patients in nursing home in Bandung. Univariate analysis using proportion and bivariate analysis using Chi-Square test to determine the relationship between risk factors with dementia. Risk factors consist of age, education, gender, and history of disease. The result showed that as many as 67.2% in the age group of 75-90 years old, 41.4% had elementary school, 84.5% of them are female, and 65.5% had hypertension. Bivariate analysis found a relationship between age, education, gender, and hypertension with dementia (p <0.05). It can be concluded that age, education, gender, and hypertension contributed to dementia.

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“…It has been proposed that the CSVD-dementia association may be coincidental due to both conditions' prevalence in older adults. 32 Not all individuals with CSVD develop dementia, 33 implying that other factors may play a greater role. In our research, we aimed to gather clinical evidence supporting the vascular theory and clarify whether vascular pathology is a key component of dementia pathogenesis.…”

Section: Discussionmentioning

confidence: 99%

Nonarteritic Anterior Ischemic Optic Neuropathy and the Risk of Dementia

Kim,

Han,

Jung

et al. 2024

Neurology

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Background and ObjectivesWhile emerging theories suggest that vascular dysfunction may occur concurrently with the amyloid cascade in Alzheimer disease (AD) pathogenesis, the role of vascular components as primary neurodegeneration triggers remains uncertain. The aim of this retrospective, populationbased cohort study conducted in Korea was to explore the link between nonarteritic anterior ischemic optic neuropathy (NAION) and dementia risk. MethodsIn this nationwide, population-based, retrospective cohort study, we identified newly diagnosed NAION from 2010 to 2017 in the Korean National Health Insurance Service database. The primary outcome was new dementia diagnoses confirmed by new ICD-10 claims coupled with antidementia medication prescriptions. We assessed dementia risk using hazard ratios (HRs) with 95% CIs over an average 2.69-year follow-up after a 1-year lag period. ResultsThe cohort consisted of 42,943 patients with NAION and 214,715 age-matched and sexmatched controls without NAION (mean age 61.37 years ± 10.75 SD, 55.48% female).

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Association between cardiovascular disease and dementia

Cited by 6 publications

References 38 publications

Factors Associated with Recovered Functionality After Hip Fracture in Non-Institutionalized Older Adults: A Case-Control Study Nested in a Cohort

Factors Associated with Recovered Functionality After Hip Fracture in Non-Institutionalized Older Adults: A Case-Control Study Nested in a Cohort

Risk Factors of Dementia in Elderly at Nursing Home

Nonarteritic Anterior Ischemic Optic Neuropathy and the Risk of Dementia

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