Visual agnosia and prosopagnosia secondary to melanoma metástases: Case report

Abstract

The association of visual agnosia and prosopagnosia with cerebral metastasis is very rare. The presence of symmetric and bilateral cerebral metastases of melanoma is also uncommon.We report the case of a 34 year-old man who was admitted to hospital with seizures and a three-month history of headache, with blurred vision during the past month. A previous history of melanoma resection was obtained. CT of the skull showed bilateral heterogeneous hypodense lesions in the occipito-temporal regions, with a ring pattern of contrast enhancement. Surgical resection of both metastatic lesions was performed after which the patient developed visual agnosia and prosopagnosia. On follow-up, he showed partial recovery of visual agnosia, while prosopagnosia was still evident. The relevance of this case is the rare presentation of metastatic malignant melanoma affecting homologous occipito-temporal areas associated with prosopagnosia and associative visual agnosia.

Congenital prosopagnosia: A case report

“…There is growing evidence that a familial factor is involved in many cases of CP and thus, formal testing establishing face processing impairments in additional family members could further assist in the differential diagnosis of CP as opposed to acquired prosopagnosia (AP). 5 , 6 …”