Potenciais evocados auditivos tardios em indivíduos com queixa de zumbido

Abstract

Summary Long latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level. Aim to characterize the LLAEP in individuals with and without tinnitus exposed to occupational noise. Method Cross-sectional contemporary cohort, prospective study. Sixty subjects exposed to occupational noise, ranging in age from 29 to 50 years underwent LLAEP assessment; 30 of them had tinnitus complaint and 30 did not have tinnitus. Results we observed significant statistical difference regarding the mean values of latencies of waves N1 (p<0.001), P2 (p=0.002) and P300 (p=0.039) when we compared individuals with and without tinnitus. In individuals with tinnitus we also noticed a greater number of altered results concerning components N1 (60%) and P2 (66.7%), although only component P2 presented significant statistical difference (p=0.010). For the LLAEP, the latency increase was the only type of alteration found (p=1.000). We found a greater association between bilateral tinnitus and bilateral alteration for all components N1(73%), P2(73%) and P300(50%). Conclusion It is relevant to study LLAEP in individuals with tinnitus exposed to high occupational sound pressure levels.

Comparative analysis of acoustic therapies for tinnitus treatment based on auditory event-related potentials

“…In fact, patients with tinnitus pay an increased attention to their interior sound, even when they are surrounded by noise, which is why tinnitus worsens into a silent environment. Similar findings regarding the higher latencies (N1, P2, P3) and amplitude reduction (P2, P3) have been observed in tinnitus with sensorineural hearing loss ( Attias et al, 1993 ; Jacobson and McCaslin, 2003 ; Santos Filha and Matas, 2010 ; Said, 2012 ; Elmorsy and Abdeltawwab, 2013 ; Houdayer et al, 2015 ). Refer to Table 1 .…”

“…AERPs were used mainly to find abnormalities in amplitudes and latencies between controls and tinnitus patients, but not to evaluate treatment effects. In all those studies, the most common method for evoking potentials was the oddball paradigm, and the most common stimuli in use was a 1 kHz pure tone, either as the target stimulus ( Attias et al, 1993 ) or as a constant sound ( Santos Filha and Matas, 2010 ; Said, 2012 ; Yang et al, 2013 ). There are many reasons to choose this sound as the experimental stimulus.…”

“…However, patients with sensorineural hearing loss without tinnitus presented no alteration, as healthy subjects (Said, 2012). Differences between bilateral tinnitus and unilateral tinnitus have also been described, with the latency of N1 being reduced in bilateral tinnitus, while the amplitude of N1-P2 increased in the ear with unilateral tinnitus (Santos Filha and Matas, 2010;Houdayer et al, 2015). Peripheral hearing loss can directly affect the P3 latency as well as the latency and amplitude of the waves N1 and N2 (Hall et al, 1990), but apparently P3 is not influenced by moderate peripheral hearing loss.…”

“…In addition, the AUC difference of these two grand averages (S f -S 0 ) is topographically plotted in µV. (Santos Filha and Matas, 2010;Said, 2012;Yang et al, 2013). There are many reasons to choose this sound as the experimental stimulus.…”

The characteristics of cognitive impairment in subjective chronic tinnitus

“…Objective measures like P300 ERPs may thus be appropriate to supplement studies involving cognitive performance assessments. N2 and P3 latencies are related to stimulus evaluation processes such as encoding and classification (Giroud, Lemke, Reich, Matthes, & Meyer, 2017;Ozdemir, Demiroren, Demir, & Serin, 2014;Santos Filha & Matas, 2010). In this study, there was a significant difference in N2 and P3 latencies between the two tinnitus subgroups, further illustrating that cognitive deficits might be characteristic of tinnitus.…”