Magnetic Resonance Imaging of Low-Grade Fibromyxoid Sarcoma

Torriani, Martin; Etchebehere, Maurício; Amstalden, Eliane Maria Ingrid; Ouellette, Hugue A.

doi:10.1590/s1807-59322006000300012

Cited by 10 publications

(3 citation statements)

References 11 publications

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“…[5][6][7][8] Of the nine reported cases, the border was circumscribed in six cases, infi ltrative in one case, and not described in two cases. Our cases had a circumscribed border in two cases and an infi ltrative border in one case.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7][8][9][10] For our fi rst two cases, in which CT studies alone were performed, strongly enhancing areas correlated with the hypercellular zone, and weakly enhancing areas correlated with the myxoid zone with less cellularity, or hyalinization. These correlations appear to contradict those of previous reports, but the well-enhancing hypercellular zone in our case may be more abundant in free water within the fi brous stroma, or poorly enhancing myxoid areas may be more abundant in myxoid stroma, and the cellular or vascular densities were sparse.…”

Section: Discussionmentioning

confidence: 99%

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Imaging findings of thoracic low-grade fibromyxoid sarcoma: report of three cases

et al. 2009

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Imaging findings of low-grade fibromyxoid sarcoma (LGFMS) are reported in three thoracic cases, two in the mediastinum and one in the chest wall. The multinodular intralesional structure with strongly enhancing components in the periphery and components with abrupt transition may be suggestive of LGFMS. Strongly enhancing areas correlated with the hypercellular zone, and weakly enhancing areas correlated with the myxoid zone with less cellularity, or hyalinization. No differences in vasculature densities between the myxoid and fibrous zones were demonstrated.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Imaging findings of thoracic low-grade fibromyxoid sarcoma: report of three cases

et al. 2009

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“…The importance of a correct diagnosis is stressed in literature, requiring integration of the clinical signs (a clearly delineated skeletal muscle mass, slow growth, a mean size of 10 cm) [3] with instrumental findings (at MRI the lesion generally appears hypointense in T1 and hyperintense in T2) [4] and with the subsequent anatomo-histology (focal infiltration of the adjacent tissues despite the presence of a surrounding pseudo-capsule, low or moderate cellularity, alternation of fibrous and myxoid areas, a multinodular aspect, few mitotic figures, absence of nuclear pleomorphism) [5] and immuno-histochemistry results (strong positivity of the tumoral cells to vimentin and smooth muscle actin and the presence of supernumerary chromosomal rings) [6]. With a diagnosis of LGFMS, the administration of chemotherapy will be excluded since this is more appropriate in many other sarcomas with high-grade malignancy.…”

Section: Introductionmentioning

confidence: 99%

Low-grade fibromyxoid sarcoma of the medial vastus: a case report

et al. 2010

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Low-grade fibromyxoid sarcoma (LGFMS) was first described by Evans in 1987, and since then, just over 150 cases have been reported, showing the rarity of this tumor. We report the clinical case of a 56-year-old man with a swelling on the distal third of the left thigh. The mass had grown in the course of 1 year and was surgically excised, obtaining complete resolution. Immuno-histological examination demonstrated the lesion to be a LGFMS, defined as a benign tumor but with a high incidence of local and distant recurrence (5-10%). At 2-year follow-up the patient was disease-free, confirming the efficacy of the surgical excision. In literature, the frequency of incomplete excision of LGFMS due to inappropriate diagnosis is stressed. It is this element that contributes most to the high rate of recurrence. We recommend that the eventuality of observing this rare tumor be borne in mind, and that care be taken to perform a complete, ample excision.

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Imaging of the most frequent superficial soft-tissue sarcomas

et al. 2010

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Superficial soft-tissue sarcomas are malignant mesenchymal tumors located within the cutaneous and/or subcutaneous layers. Most superficial soft-tissue sarcomas are low-grade tumors; yet, the risk of local recurrence is high, and initial wide surgery is the main prognostic factor. Some of these superficial sarcomas may grow, following an infiltrative pattern, and their real extent may be underestimated clinically. Imaging techniques are useful to determine precisely the real margins of the tumor, especially in cases of clinically doubtful or recurrent or large superficial lesions. Imaging tools enable one to determine the relationship with the superficial fascia separating the subcutaneous layer from the underlying muscle. In our institution ultrasonographic examination is followed by magnetic resonance (MR) imaging when the size of the lesion exceeds 3-5 cm. Imaging assessment is performed prior to biopsy, enabling optimal surgical management. Imaging features of the main superficial sarcomas are detailed in the following article, according to their major locations: those arising in the epidermis and/or dermis, which are most often diagnosed by dermatologists, and the subcutaneous sarcomas.

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Magnetic Resonance Imaging of Low-Grade Fibromyxoid Sarcoma

Cited by 10 publications

References 11 publications

Imaging findings of thoracic low-grade fibromyxoid sarcoma: report of three cases

Imaging findings of thoracic low-grade fibromyxoid sarcoma: report of three cases

Low-grade fibromyxoid sarcoma of the medial vastus: a case report

Imaging of the most frequent superficial soft-tissue sarcomas

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