Abstract:Two different and interrelated steps are involved in the assessment of active sweat glands: stimulation of sweating and its subsequent recording and quantification.Sweat activation has been promoted by simple thermal stimulation, by intradermal injection of drugs such as methylcholine, 1 and by dermal introduction of such drugs using iontophoresis. 2,3 Gibson and Cooke's device for iontophoresis, one of the most employed devices, 2 provides DC current and uses large lead electrodes lined with porous material. … Show more
Although data were acquired on human palms, these techniques show great promise for a better understanding of sweat secretion physiology and should be helpful to improve the efficacy of antiperspirant formulations.
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