Correlation of lung function and respiratory muscle strength with functional exercise capacity in obese individuals with obstructive sleep apnea syndrome

Abstract

In this sample of obese subjects with untreated OSAS, lung function, inspiratory muscle strength, and exercise tolerance were all below normal. In addition, we found that a decline in lung function, but not in respiratory muscle strength, was associated with exercise tolerance in these patients.

The Effect of Maternal Pulmonary Function Test Parameters on Umbilical Cord Blood Gas and the Duration of Labor

“…In a study on obese obstructive sleep-apnea patients, a significant positive correlation was found between FVC and FEV1 and the distance covered in the incremental shuttle walk test (ISWT). This result suggested that low values detected in PFTs may adversely affect exercise tolerance [30]. After the cervix is fully opened, the most important force in expelling the fetus is the intra-abdominal pressure of the pregnant woman.…”

Contribution of lung function in predicting distance covered in the 6-min walk test in obese Brazilian women

“…In this context, pulmonary function tests may be useful to assess whether a physiological change can be explained by the effects of obesity on the respiratory system. An increase in the volume of adipose tissue in the perithoracic and abdominal regions reduces the compliance of the thoracic cavity and lung volumes and impairs diaphragmatic function, making the respiratory muscles work harder ( 11 ). The overall effect is an overload of the respiratory muscles, which increases respiratory effort, peak oxygen uptake (peak VO 2 ), and energy expenditure ( 10 ).…”

Reflections on the article “Correlation of lung function and respiratory muscle strength with functional exercise capacity in obese individuals with obstructive sleep apnea syndrome”

“…First, we would like to congratulate Carvalho et al on their article published in the JBP entitled “Correlation of lung function and respiratory muscle strength with functional exercise capacity in obese individuals with obstructive sleep apnea syndrome” (OSAS), 1 a matter of extreme importance for all professionals working in this area; this clinical condition affects a large number of people, with a direct impact on their quality of life.…”

“…An important observation to be made about the aforementioned study 1 is that it has a cross-sectional design, which does not establish causality, that is, it is not possible to know whether the changes in lung function and respiratory muscle strength are due to either obesity or OSAS alone. Support for the first hypothesis may be evidenced in a study by Melo et al, 2 who reviewed studies of lung function in obese individuals and observed reductions in total lung capacity and FVC, accompanied by a reduction in FEV 1 ; those were the key findings across all samples, suggesting that the presence of a restrictive respiratory pattern is associated with obesity.…”

“…What can be perceived is that decreased lung capacity is already a characteristic of obesity, even in the absence of comorbid OSAS 2 . A study by Tassinari et al, 3 cited by the study in question, 1 reported that no lung function or respiratory muscle impairment was observed in normal-weight OSAS patients and that there were similarities between that group of patients and healthy subjects.…”