Angiosarcoma of the lung

Grafino, Mónica; Alves, Paula M.; Almeida, Margarida; Garrido, Patricia; Hasmucrai, Direndra; Teixeira, E.; Sotto-Mayor, Renato

doi:10.1590/s1806-37562016000000193

Cited by 13 publications

(29 citation statements)

References 10 publications

(42 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mitosis, necrosis, and hemorrhages are frequently seen. [6][7][8] An immunohistochemical study is required for a definitive diagnosis. Markers include factor VIII-related antigen, lectin, and CD31, which can indicate the tumor is of endothelial origin.…”

Section: Discussionmentioning

confidence: 99%

Primary pulmonary angiosarcoma presenting as Pancoast tumor

Sayan

Valiyev

Akarsu

et al. 2021

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Primary pulmonary angiosarcoma presenting as Pancoast tumor

Sayan

Valiyev

Akarsu

et al. 2021

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

show abstract

“…24 Radiation and chemotherapy have been attempted, but the results have not been encouraging. 25 Chemotherapy agents such as doxorubicin/ifosfamide and docetaxel/gemcitabine have been reported to be useful in some studies. 26 All of our 3 patients were treated with chemotherapy, 2 underwent surgery, and one was treated with radiation therapy.…”

Section: Discussionmentioning

confidence: 99%

Primary pulmonary angiosarcoma: case reports and review of the literature

Virarkar

Tayyab

Thampy

et al. 2019

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

Pulmonary artery angiosarcoma is a rare malignant vascular tumor with an aggressive clinical course and a poor prognosis. Hemoptysis and shortness of breath have been reported as common clinical presentations. The exact clinicopathology is unknown. A tissue specimen obtained by percutaneous fine-needle aspiration cytology or open/thoracoscopic biopsy can confirm the diagnosis based on histopathological and immunohistochemical features. The differential diagnosis includes pulmonary thromboembolism, vascular malformations, and lung carcinoma. There is a paucity of literature describing this tumor, with only a few case reports available. There is also a lack of standardized guidelines for management, which further worsens the survival outcome. We report 3 cases of pulmonary artery angiosarcoma and review the recent literature.

show abstract

“…The early diagnosis is very difficult due to non-specific signs and symptoms presented by the patients. The majority of reports emphasize the following symptoms: (1) hemoptysis (the most common sign related to the vessel injury [7,9], (2) cough, dyspnea (related to local growth) [7], (3) chest pain [1], (4) non-specific symptoms: weight loss, malaise, fatigue, fever [5,7,10]. Nevertheless, some patients may present the tration [6,11,12].…”

Section: Discussionmentioning

confidence: 99%

“…This is because specific endobronchial lesions are uncommon. In three patients a tumor or mass occluding bronchus and slowly growing hemorrhagic tumor were reported [10,15,16]. Also, tissue samples obtained by transbronchial biopsy are rarely sufficient to diagnose the nature of the tumor.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Hemoptysis in a Patient with Multifocal Primary Pulmonary Angiosarcoma

Piechuta¹,

Przybyłowski²,

Szołkowska³

et al. 2016

Advances in Respiratory Medicine

View full text Add to dashboard Cite

Primary pulmonary angiosarcoma (PPA) is a rare tumour arising from arterial or venous pulmonary vessels of various size. It is characterized by aggressive course and poor prognosis. The early diagnosis is difficult due to diverse clinical and radiological manifestations. We present a case report of 70 year-old man, active cigarette-smoker, with a 2-month history of non-massive hemoptysis. The thorax CT revealed several solid pulmonary nodules surrounded by areas of ground glass opacity. As bronchoscopy failed to deliver adequate tissue samples, video assisted thoracic surgery (VATS) with pleura and lung biopsy was necessary. Histopathological findings were consistent with pulmonary angiosarcoma. Since no extrapulmonary lesions were demonstrated, the final diagnosis of primary pulmonary angiosarcoma was made. The patient died three months after the onset of symptoms. Our case report highlights that differential diagnosis in patients with hemoptysis and pulmonary nodules should include primary pulmonary sarcoma. Case presentationA 70-year-old man was referred to our department from one of municipal hospitals in January 2016 with a 2-month history of non-massive hemoptysis (daily volume of expectorated blood was approximately 15 ml). The patient also reported weight loss of 3 kg during the last month, general weakness and mild recurrent epistaxis. His past medical history included arterial hypertension and chronic sinusitis, both diagnosed approximately 10 years ago. He had also undergone endovascular stent grafting of abdominal aorta aneurysm as well as transurethral resection of the prostate due to benign prostatic hyperplasia. He was an active cigarette-smoker with a history of 52 pack-years of tobacco smoking. During the hospitalisation in the municipal hospital two pulmonary nodules in the left lower lobe were found in chest radiograph. These findings were confirmed in thorax CT scan which also showed ground glass areas surrounding the nodules (halo sign).On admission the patient's general condition was satisfactory. His vital signs were within normal range: arterial blood pressure was 120/80 mm Hg, heart rate 80 beats per minute, transcutaneous arterial oxygen saturation 93% while breathing room air. Dullness to percussion and diminished breath sounds over the left lower lung field was noted on physical examination. Except these findings the physical examination did not reveal any relevant abnormalities.The results of laboratory studies showed normocytic anaemia (hemoglobin level 90.5 g/L), an elevated peripheral white blood cell count (WBC)

show abstract

Angiosarcoma of the lung

Cited by 13 publications

References 10 publications

Primary pulmonary angiosarcoma presenting as Pancoast tumor

Primary pulmonary angiosarcoma presenting as Pancoast tumor

Primary pulmonary angiosarcoma: case reports and review of the literature

Hemoptysis in a Patient with Multifocal Primary Pulmonary Angiosarcoma

Contact Info

Product

Resources

About