Epidemiological aspects of and risk factors for wheezing in the first year of life

Abstract

OBJECTIVE: To determine, in a sample of infants, the prevalence of and risk factors for occasional wheezing (OW) and recurrent wheezing-wheezy baby syndrome (WBS). METHODS: Parents of infants (12-15 months of age) completed the International Study of Wheezing in Infants questionnaire. RESULTS: We included 1,269 infants residing in the city of Blumenau, Brazil. Of those, 715 (56.34%) had a history of wheezing, which was more common among boys. The prevalences of OW and WBS were 27.03% (n = 343) and 29.31% (n = 372), respectively. On average, the first wheezing episode occurred at 5.55 ± 2.87 months of age. Among the 715 infants with a history of wheezing, the first episode occurred within the first six months of life in 479 (66.99%), and 372 (52.03%) had had three or more episodes. Factors associated with wheezing in general were pneumonia; oral corticosteroid use; a cold; attending daycare; having a parent with asthma or allergies; mother working outside the home; male gender; no breastfeeding; and mold. Factors associated with WBS were a cold; physician-diagnosed asthma; ER visits; corticosteroid use; pneumonia; bronchitis; dyspnea; attending daycare; bronchodilator use; having a parent with asthma; no breastfeeding; mother working outside the home; and a dog in the household. CONCLUSIONS: The prevalence of wheezing in the studied population was high (56.34%). The etiology was multifactorial, and the risk factors were intrinsic and extrinsic (respiratory tract infections, allergies, attending daycare, and early wheezing). The high prevalence and the intrinsic risk factors indicate the need and the opportunity for epidemiological and genetic studies in this population. In addition, mothers should be encouraged to prolong breastfeeding and to keep infants under six months of age out of daycare.

Enteroparasites, Respiratory Allergy and Other Signs and Symptoms in Childs and Youth Population of Recôncavo of Bahia – Brazil

“…Family history is a major factor in the development of allergies, which may be genetic or passed from mother to child through breast-feeding (55), and is often the main risk factor in Vol-2 Issue-1 SIFT DESK certain populations, as seen in the study of Morishita, Strufaldi, Puccini (56), where it was present in 65% of the cases. However, in the present study, the family history of allergic manifestations assumed an irrelevant role as a risk factor, corroborating Fogaça et al (57), where the main factor was previous pneumonia (for asthma).…”

Association between maternal depression and wheezing in preschool children

“…In line with the literature, we detected that anthropometric values and family socioeconomic level were significantly lower and that history of maternal asthma, rate of parental illiteracy, number of people living in the household, sibling history of asthma and rate of preterm birth were significantly higher in preschool children who were hospitalized due to recurrent wheezing attacks relative to control children [16][17][18][19][20] . In contrast to some studies, no correlation was identified between maternal smoking and wheezing attacks 21,22 .…”

Hişiltili Süt Çocuğunda Alternati̇f Tedavi̇de Bildircin Yumurtasi Anafi̇laksi̇si̇

“…Okul öncesi hışıltı çok yaygındır ve prevelansı artmaktadır (7). Bir yaşından küçük çocukların yaklaşık %37 ila %56'sı en az bir kez hışıltı atağı geçirmektedir (8,9). Hışıltı atakları hasta ve ebeveynin yaşam kalitesini bozar, sağlık hizmetlerinin kullanım sıklığını ve ekonomik maliyetleri arttırır, önemli ölçüde mortalite ve morbidite ile ilişkilidir.…”