Utility of Asthma Control Questionnaire 7 in the assessment of asthma control

Abstract

Our objective was to evaluate the reproducibility of Asthma Control Questionnaire 7 (ACQ-7) in asthma patients, comparing our results against those obtained with the Global Initiative for Asthma (GINA) criteria. We evaluated 52 patients. Patients completed the ACQ-7, underwent spirometry, and were clinically assessed to determine the level of asthma control according to the GINA criteria, in two visits, 15 days apart. The ACQ-7 cutoff for uncontrolled asthma was a score of 1.5. The ACQ-7 showed good reproducibility, with a correlation coefficient of 0.73. The ACQ-7 identified a greater number of patients with uncontrolled asthma than did the GINA criteria; according to the GINA criteria, 47 patients (90.4%) presented with partially controlled asthma.

Comparing Asthma Control Questionnaire (ACQ) and National Asthma Education and Prevention Program (NAEPP) asthma control criteria

“…Similar to other reports, 24 the ACQ appears to correlate more linearly with FEV1 than NAEPP, although a significantly higher proportion of FEV1<80% was found only in the NAEPP’s poorly controlled asthma category. Nonetheless, neither seems ideal for identifying FEV1<80% adequately due to the high chance of false positives for ACQ (68%) or alternately low sensitivity for NAEPP (49%), which translates to high likelihood of error using either metric as a predictor of lung function.…”

Adults with asthma treated with add-on omalizumab report less limitation in activities of daily living

“…The patients were assessed regarding sociodemographic data, the number of comorbidities, anxiety and depression symptoms, 6 exacerbations in the previous year, and use and dose of asthma medication. Anthropometric data, biomarkers (eosinophil and total Immunoglobulin E), the 7-item Asthma Control Questionnaire (ACQ - uncontrolled asthma if >1.50 points), 7 and lung function (Spirometer MicroLab 3500, Care Fusion ® , Ireland) 8 were also assessed. The limitation to perform ADL was analyzed using the London Chest Activity of Daily Living (LCADL) scale, 9 which has four domains (personal care, domestic, physical activity, and leisure) distributed into 15 items of ADL, each scored from 0 to 5.…”

“…Most of the participants were middle-aged and overweight, and 21 (57%) presented uncontrolled asthma. 7 Fourteen patients (38%) had been receiving add-on omalizumab therapy for 30 (9-60) months. Most patients in the conventional therapy group seemed eligible for omalizumab since they had asthma symptoms that were inadequately controlled by inhaled corticosteroids (ICS) and total Immunoglobulin E levels between 30 and 1,500 IU/mL ( Table 1 ).…”

Efeito agudo do salbutamol no sistema cardiovascular durante o exercício físico em pacientes com asma moderada ou grave: estudo aleatorizado, duplo-cego e cruzado

“…Prior to the first experimental session, patients were submitted to the Asthma Control Questionnaire (ACQ-7), duly validated 11 to assess the effectiveness of asthma control 12 . Patients were selected to perform 2 distinct experimental sessions on 2 nonconsecutive days.…”