Tomografia de coerência óptica broncoscópica

Rodrigues, Aldo Junqueira; Takimura, Celso Kiyochi; Neto, Pedro Alves Lemos; Figueiredo, Vivíane Rossi

doi:10.1590/s1806-37132012000200005

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…Probe confocal microscopy and optical coherence tomography are two potential technologies that hold promise in being able to help determine the underlying pathophysiology. 15 16…”

Section: Simple Versus Complex and Inflammatory Versus Fibroticmentioning

confidence: 99%

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Nonmalignant Central Airway Obstruction: Options for Challenging Cases

Abia‐Trujillo

Fernández-Bussy

2022

Semin Respir Crit Care Med

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Benign central airway obstruction is commonly referred as nonmalignant central airway obstruction (NMCAO). This is in part related to its lack of benign nature and significant life-quality impairment in patients. It is a pathologic entity with various etiologies and therefore a wide range of therapeutic options are available. Evidence regarding the optimal management that could provide a sustained restoration of airway patency is lacking. The lack of a common pathophysiologic pathway translating into a nonspecific symptom presenting as NMCAO has complicated treatment standardization and subsequently limited solid research to favor of one approach over another one. Our intent is to describe the limited evidence of the most utilized nonsurgical treatment for NMCAO as well as some upcoming promising therapeutic options such as mitomycin C injection, microdebrider, biodegradable stents, radiotherapy, Hybrid Knife, and endoluminal spray cryotherapy. Our goal with this manuscript is to motivate other authors to venture into prospective, multicenter, open-label trials aimed to describe long-term outcomes in patients with NMCAO.

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“…Probe confocal microscopy and optical coherence tomography are two potential technologies that hold promise in being able to help determine the underlying pathophysiology. 15 16…”

Section: Simple Versus Complex and Inflammatory Versus Fibroticmentioning

confidence: 99%

“…Probe-based confocal laser endomicroscopy and optical coherence tomography can potentially help define the micropscopic environment of the surrounding tissue and better determine the underlying inflammatory nature. 15 16…”

Section: Choosing Wisely … a Tailored Approach For Challenging Casesmentioning

confidence: 99%

Nonmalignant Central Airway Obstruction: Options for Challenging Cases

Abia‐Trujillo

Fernández-Bussy

2022

Semin Respir Crit Care Med

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Bronchoscopy for the diagnosis of peripheral lung lesions

Dhillon

Harris

2017

J. Thorac. Dis.

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Peripheral pulmonary lesions (PPLs) are generally considered as lesions in the peripheral one-third of the lung although a precise definition and radiographic anatomical landmarks separating central and peripheral lesion does not yet exist. The radiographic detection of such lesions has increased significantly with the adoption of lung cancer screening programs. These lesions are not directly visible by regular flexible bronchoscopes as they are usually distal to the lobar and segmental bronchi. Traditionally, depending on location and clinical stage at presentation, these lesions were typically sampled by computerized tomography (CT) guided needle or surgical biopsy although some centers also used ultrasound and fluoroscopy guided percutaneous needle biopsy. Due to lack of direct visualization, the yield for bronchoscopic guided sampling especially of the small <2 cm pulmonary nodules was very low. Therefore, sampling has been preferentially performed by percutaneous CT guidance, which had high yield of above 90% but it comes at the cost of higher risk complications like pneumothorax with reported rate of 15% to 28%. Directly proceeding to surgical resection is also considered in appropriate candidates with high suspicion of malignancy without any evidence of distant metastasis but the proportion of such cases of lung cancer is low. The manuscript discussed the various bronchoscopic diagnostic modalities for peripheral pulmonary lesions. It is important to note that most of the studies in this field are relatively small, not randomized, suffer from selection bias, have considerable heterogeneity in sampling methodology/instruments and usually have been performed in high volume institutions by dedicated highly experienced proceduralists. The prevalence of malignancy in most of the reported cohorts has also been high which may result in higher diagnostic yields. All these factors need to be kept in mind before generalizing the results to individual centers and practices.

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Tomografia de coerência óptica broncoscópica

Cited by 2 publications

References 28 publications

Nonmalignant Central Airway Obstruction: Options for Challenging Cases

Nonmalignant Central Airway Obstruction: Options for Challenging Cases

Bronchoscopy for the diagnosis of peripheral lung lesions

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