Amiloidose traqueobrônquica

Silva, Luciano Müller Corrêa da; Bellicanta, Jamila; Marques, Renata Diniz; Silva, Luiz Carlos Corrêa da

doi:10.1590/s1806-37132004000600014

Cited by 4 publications

(17 citation statements)

References 13 publications

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“…(2,5,6) There are various different forms of amyloidosis. (1) Amyloidosis can be classified, through immunohistochemistry, into three types: reactive (AA type); primary idiopathic (AL type); and transthyretinrelated amyloidosis (ATTR type). The AA type of amyloidosis, which is derived from the serum amyloid A protein, can be hereditary or can result from chronic infectious processes, having been associated with familial Mediterranean fever and tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

“…This form of amyloidosis rarely manifests as a respiratory disease. The AL type of amyloidosis (light-chain amyloidosis), which is the most common type, (1) is considered a systemic process and , due to the large deposition of cleaved products of immunoglobulin, manifests as heart failure, renal insufficiency, or nephropathy.…”

Section: Discussionmentioning

confidence: 99%

“…(5) The ATTR type of amyloidosis is associated with senile systemic amyloidosis and most frequently manifests as cardiovascular dysfunction, polyneuropathy or renal impairment. (1) There have been few reported cases of systemic AA amyloidosis affecting the lungs. However, the AL type has been a unanimous finding in studies of fibrillary protein sequencing.…”

Section: Discussionmentioning

confidence: 99%

“…(1)(2)(3) It is a generic term for a heterogeneous group of diseases, including Alzheimer's disease and type 2 diabetes mellitus. It can be hereditary or acquired, potentially fatal or a merely accidental finding.…”

Section: Introductionmentioning

confidence: 99%

“…(1,3) The objective of the present study was to report the clinical case of a patient with pulmonary amyloidosis (nodular type) diagnosed at the Serviço de Pneumologia e Cirurgia Torácica do Hospital Monte Sinai de Juiz de Fora (SPCT-HMS-JF, Pulmonology and Thoracic Surgery Clinic of the Juiz de Fora Monte Sinai Hospital).…”

Section: Introductionmentioning

confidence: 99%

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Amiloidose pulmonar: relato de caso de achado radiológico da apresentação nodular em grande fumante

Montessi

Almeida

Vieira³

et al. 2007

J. bras. pneumol.

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Pulmonary amyloidosis is a rare disease, characterized by extracellular deposition of fibrillary protein in the lungs. Amyloidosis is a generic term for a heterogeneous group of diseases, including Alzheimer's disease and type 2 diabetes mellitus. In the respiratory system, it appears in various forms: tracheobronchial; nodular pulmonary; and alveolar septal (diffuse parenchymal). We present the case of a woman who was a 20 pack-year smoker and had nodular pulmonary amyloidosis, as diagnosed through tests performed prior to laparoscopic cholecystectomy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Amiloidose pulmonar: relato de caso de achado radiológico da apresentação nodular em grande fumante

Montessi

Almeida

Vieira³

et al. 2007

J. bras. pneumol.

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Amiloidose pulmonar com apresentação traqueobrônquica: relato de caso clínico

Maso¹,

Dalbosco²,

Carneiro³

et al. 2022

Rev. Med. (São Paulo)

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Introdução: Amiloidose é o termo utilizado para designar doenças que fazem deposição extracelular de proteínas fibrilares patológicas em órgãos e tecidos, podendo ser sistêmica ou restrita a um único órgão. As manifestações clínicas são diversas, como cardiomiopatia, falência renal, esplenomegalia, problemas intestinais, neuropatias, problemas pulmonares, entre outros. Objetivo: relatar um caso clínico de paciente com amiloidose traqueobrônquica. Metodologia: revisão de bibliografias em comparação ao relato de caso, o qual foi descrito a partir de dados retirados do prontuário e de exames complementares da paciente. Caso clínico: paciente do sexo feminino, 70 anos, procurou assistência médica por dorsalgia, apresentando também chiado, tosse seca, dispneia paroxística noturna e ortopneia. Realizou-se investigação diagnóstica durante a internação, na qual biópsia da mucosa traqueobrônquica e coleta de lavado alveolar foram positivos para o teste Vermelho Congo, o que confirmou o diagnóstico de amiloidose. A paciente, então, foi encaminhada para terapia de ablação a laser. Conclusão: portanto, diante de um paciente com quadro clínico inspecífico e suspeita diagnóstica principal de amiloidose pulmonar, é imprescindível investigar e descartar diagnósticos diferenciais como neoplasia ou discrasia de células plasmáticas. Para isso, é necessário que haja alta precisão na análise dos exames de imagem, de modo a sugerir esse diagnóstico, o qual deve ser confirmado através da fibrobroncoscopia com biópsia de tecido brônquico, que através da coloração Vermelho do Congo, evidenciará presença de substância amorfa e birrefringente, compatível com substância amiloide.

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Amiloidose traqueobrônquica primária

et al. 2008

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A retired, hypertensive 67-year-old male, a former smoker and alcoholic, was referred to our facility with complaints of progressive dyspnea, wheezing and chest pain for the last 6 months. A chest X-ray obtained 8 years previously showed right hilar enlargement. He also had a long-standing history of episodic hemoptysis that ceased 10 years prior, together with a history of recurrent respiratory infections. Upon physical examination, he presented diminished breath sounds and slight crackles at the lung bases. A second chest X-ray revealed no changes in comparison with the first. The IntroductionThe amyloidoses constitute a group of diseases in which extracellular protein folding, or rather misfolding, plays a prominent role.(1) The disease can be hereditary or acquired and can be systemic or localized. Some patients are asymptomatic, whereas others exhibit a range of symptoms, and, in certain cases, the disorder can even be severe and life-threatening.(2) Tracheobronchial amyloidosis is an uncommon localized form of amyloidosis, characterized by amyloid deposits restricted to the trachea, main bronchi and segmental bronchi. AbstractTracheobronchial amyloidosis is an uncommon localized form of amyloidosis, characterized by amyloid deposits restricted to the trachea, main bronchi and segmental bronchi. We present the case of a retired 67-year-old man with long-term progressive dyspnea, wheezing and chest pain. A diagnosis of tracheobronchial amyloidosis was made after the third fiberoptic bronchoscopy and histological confirmation through Congo red staining of tissue samples.Keywords: Amyloidosis/trachea; Bronchoscopy; Tracheal diseases/diagnosis. ResumoA amiloidose traqueobrônquica é uma forma pouco comum de amiloidose localizada, caracterizada por depósitos amilóides limitados à traquéia, brônquios principais e brônquios segmentares. Nós apresentamos o caso de um homem aposentado de 67 anos com dispnéia progressiva de longa data, sibilância e dor torácica. O diagnóstico de amiloidose traqueobrônquica foi realizado após três fibrobroncoscopias e confirmação histopatológica com coloração vermelho congo.Descritores: Amiloidose/traquéia; Broncoscopia; Doenças da traquéia/diagnóstico.

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Amiloidose traqueobrônquica

Cited by 4 publications

References 13 publications

Amiloidose pulmonar: relato de caso de achado radiológico da apresentação nodular em grande fumante

Amiloidose pulmonar: relato de caso de achado radiológico da apresentação nodular em grande fumante

Amiloidose pulmonar com apresentação traqueobrônquica: relato de caso clínico

Amiloidose traqueobrônquica primária

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