2007
DOI: 10.1590/s1806-37132007000300017 View full text |Buy / Rent full text
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Jorge Montessi,
Edmilton Pereira de Almeida,
João Paulo Vieira
et al.

Abstract: Pulmonary amyloidosis is a rare disease, characterized by extracellular deposition of fibrillary protein in the lungs. Amyloidosis is a generic term for a heterogeneous group of diseases, including Alzheimer's disease and type 2 diabetes mellitus. In the respiratory system, it appears in various forms: tracheobronchial; nodular pulmonary; and alveolar septal (diffuse parenchymal). We present the case of a woman who was a 20 pack-year smoker and had nodular pulmonary amyloidosis, as diagnosed through tests perf… Show more

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“…In certain diseases, the clinically significant amyloid deposition can be limited to one organ. [20][21][22] The involvement of kidneys repeatedly presents only as asymptomatic proteinuria or nephrotic syndrome. However, the primary deposition may be confined to blood vessels or tubules with progression to renal failure with little or no proteinuria.…”
Section: Resultsmentioning
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rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…In certain diseases, the clinically significant amyloid deposition can be limited to one organ. [20][21][22] The involvement of kidneys repeatedly presents only as asymptomatic proteinuria or nephrotic syndrome. However, the primary deposition may be confined to blood vessels or tubules with progression to renal failure with little or no proteinuria.…”
Section: Resultsmentioning
“…Amyloidosis is a generic term for a heterogeneous group of associated diseases with abnormal deposition of fibrillar proteins. 20 It is classified according to the type of precursor protein that form amyloid fibrils and distribution of amyloid deposition in a localized form or systemically. 20 The clinical manifestations of amyloidosis depend on the type of precursor protein, its tissue distribution, and amount of deposition of the amyloid substance.…”
Section: Discussionmentioning
“…3 As primeiras são localizadas e a última sistémica. 4,6 Em casos raros pode também atingir a pleura, gânglios intratorácicos e os vasos. 1 A localização mais comum é a laríngea e a traqueobrôn-quica, sob a forma de nódulos pseudo-tumorais (15%) ou de placas submucosas multifocais (85%).…”
Section: Discussionunclassified
“…A imunohistoquímica identifica o tipo de fibrilas, mas não foi realizada nos casos descritos. 1,4 O diagnóstico de amiloidose sistémica implica a realização de biopsia, sendo que o estudo da gordura peri-umbilical ou do recto apresentam uma sensibilidade superior a 90%.…”
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