Increased ultrasensitive C-reactive protein is not associated with obesity in hospitalized heart failure patients

Abstract

Objective:To evaluate the association between obesity and levels of high-sensitivity C-reactive protein (hs-CRP) in patients with heart failure admitted to a tertiary hospital.Methods:Cross-sectional study with a consecutive sampling of hospitalized patients with heart failure. Sociodemographic and clinical data were collected, and the nutritional status was assessed through indicators such as body mass index (in kg/m2), waist circumference (in cm), waist-hip ratio, triceps skinfold (in mm) and subscapularis skinfold (in mm). Neck circumference (in cm) was measured as well as serum levels of hs-CRP, in mg/L.Results:Among 123 patients, the mean age was 61.9±12.3 years and 60.2% were male. The median of hs-CRP was 8.87mg/L (3.34 to 20.01). A tendency to an inverse correlation between neck circumference and hs-CRP was detected (r=-0.167; p=0.069). In the multiple linear regression analysis, after adjustment for age, disease severity (NYHA classification III and IV, low ejection fraction, left ventricular dysfunction during diastole), and infectious conditions there was an inverse association between hs-CRP and neck circumference (ß=-0.196; p=0.03) and subscapularis skinfold (ß=-0.005; p=0.01) in the total sample, which was not maintained after the stratification by sex.Conclusion:Increased levels of hs-CRP in patients hospitalized for heart failure were not associated with obesity.

Neck circumference in Latin America and the Caribbean: A systematic review and meta-analysis

“…The most frequently studied patients were those with Obstructive Sleep Apnea - Hypopnea Syndrome (OSAHS) (22) 53 , 54 , 58 – 62 , 64 – 69 , 74 , 75 , 79 , 81 , 86 , 87 , 90 , 94 , 97 , 98 and obesity (13) 52 , 71 , 73 , 80 , 82 – 85 , 91 , 92 , 95 , 99 , 100 ; other diseases included HIV/AIDS, sleep disorders, bronchiectasis, depression, stroke, epilepsy, hepatic and cardiovascular pathologies. The instrument or methodology to measure NC was reported in 29 studies 54 – 57 , 60 , 63 , 65 – 67 , 69 – 71 , 73 , 77 , 80 – 82 , 84 , 86 , 88 – 93 , 95 , 97 , 99 , 100 . We found 1 report 53 , which contributed with 2 estimates (e.g., one report provided more than one set of estimates).…”

PCR e PCR-US como indicador de risco em doenças crônicas não-transmissíveis: uma revisão

“…Entre as condições de saúde ou doenças que foram alvo das pesquisas selecionadas nessa revisão, destacam-se a Pré-eclâmpsia 31 , Diabetes Mellitus Tipo 1 32 , doença obstrutiva de artérias carótidas 33 , Infl amação de baixo grau em crianças e adolescentes 34 , Diabetes mellitus tipo 2 (DM2) e hipertensão arterial sistêmica 50 , Hipertensão e Obesidade Central 36 , Obesidade 37 , Disfunção erétil 38 , Obesidade e cirurgia bariátrica 39 , Doença arterial coronariana 40 , pré-hipertensão 41 , artrite reumatoide 42 , diabetes e cirurgia bariátrica 44 , Obesidade e cirurgia bariátrica 45 , insufi ciência cardíaca 46 , Obesidade e cirurgia bariátrica 47 .…”