Influence of assessment site in measuring transcutaneous bilirubin

Abstract

Objective:To investigate the influence of the site of measurement of transcutaneous bilirubin (forehead or sternum) in reproducibility of results as compared to plasma bilirubin.Methods:A cohort study including 58 term newborns with no hemolytic disease. Transcutaneous measurements were performed on the forehead (halfway between the headline and the glabella, from the left toward the right side, making consecutive determinations, one-centimeter apart) and the sternum (five measurements, from the suprasternal notch to the xiphoid process with consecutive determinations, one-centimeter apart) using Bilicheck® (SpectRx Inc, Norcross, Georgia, USA). The correlation and agreement between both methods and plasma bilirubin were calculated.Results:There was a strong linear correlation between both determinations of serum bilirubin at the forehead and sternum (r=0.704; p<0.01 and r=0.653; p<0.01, respectively). There was correspondence of the mean values of transcutaneous bilirubin measured on the sternum (9.9±2.2mg/dL) compared to plasma levels (10.2±1.7mg/dL), but both differ from the values measured on the forehead (8.6±2.0mg/dL), p<0.05.Conclusion:In newborn term infants with no hemolytic disease, measuring of transcutaneous bilirubin on the sternum had higher accuracy as compared to serum bilirubin measurement on the forehead.

Transcutaneous bilirubinometry: Influence of gestational age and measurement site

“…We speculate that the TcB measurement technique is not stable and consistent at the lower abdomen because abdomen is too soft in neonates, particularly tiny preterms. Forehead may be a more convenient site and better correlates with TSB, but skin over sternum may be typically light protected and therefore show greater correlation 8,9,10,11 . Recent systematic review of absolute TcB-TSB difference plots in preterms revealed minimal bias in measurement irrespective of site with pooled estimates of 0.83 12 .…”

Produção de polvilho a partir do amido de mandioca: busca de alternativas para otimização do processo de produção em indústrias polvilheiras do município de Conceição dos Ouros, Minas Gerais, Brasil

“…É uma planta de terreno aberto, quente e seco, que cresce com vigor, sem se doi: http://dx.doi.org/10. 5892/ruvrv.2012.102.178185 ramificar, possuindo período de safra de janeiro a julho (CONCEIÇÃO, 1981 Bogotá, vol. 45, 1980Bogotá, vol.…”

Transcutaneous bilirubin measurement in healthy Saudi term newborns

“… 1 Recently published studies have shown that measurement of transcutaneous bilirubin on the sternum had higher accuracy as compared to serum bilirubin measurement on the forehead. 2 , 3 2) There are numerous different transcutaneous bilirubinometers (TcBm) in the clinical setting to estimate TcB. Comparative studies have shown varied agreement of TcBm with each other and TSB.…”

“…Even the studies which concluded that either site is superior, the difference is minute to have any clinical implications. He quoted 2 studies by Conceição etal 3 and Kosorat and Khuwuthyakorn. 2 Conceição et al 3 reported that the correlation between TSB and TcB as measured at the forehead had better correlation when compared with TcB measurement from the sternum (r=0.704 versus r=0.653).…”

“…He quoted 2 studies by Conceição etal 3 and Kosorat and Khuwuthyakorn. 2 Conceição et al 3 reported that the correlation between TSB and TcB as measured at the forehead had better correlation when compared with TcB measurement from the sternum (r=0.704 versus r=0.653). However, the mean value of TcB measured at the sternum (9.9±2.2 mg/dL) compared to plasma levels (10.2±1.7 mg/dL), is better compared with the mean value of TcB measured at the forehead (8.6±2.0 mg/dL) ( p <0.05).…”