High molecular prevalence of HPV and other sexually transmitted infections in a population of asymptomatic women who work or study at a Brazilian university

Suehiro, Tamy Taianne; Gimenes, Fernanda Raphael Escobar; Souza, Raquel P.; Taura, Sérgio Ken Iti; Cestari, Rita Cristina Cardoso; Irie, Mary Mayumi Taguti; Bôer, Cinthia Gandolfi; Consolaro, Márcia Edilaine Lopes; Silva, Vânia Ramos Sela da

doi:10.1590/s1678-9946202163001

Cited by 14 publications

(24 citation statements)

References 30 publications

(49 reference statements)

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“…This scenario is not restricted to the Amazon region, given that similar sexual behavior has been observed in university students from other regions of Brazil [31,52] and from other countries, around the world [53][54][55]. Even so, as high rates of sexual infection by C. trachomatis are typical of the young populations of remote Amazonian communities [28,34], it would seem reasonable to assume that the ndings of the present study represent only the "tip of the iceberg" of the real epidemiological scenario of the infection in this region.…”

Section: Discussionmentioning

confidence: 73%

“…In Brazil, the absence of a monitoring program contributes to the unawareness of this silent epidemic and its recurrent damages, however, the annual number of hospitalizations of women with PID is over 45,000 [22]. The studies have reported prevalence of 4-20.5% in both asymptomatic women [23][24][25][26][27][28][29][30][31] and those seeking gynecological treatment [32][33][34]. The few available studies about genotyping for Brazil have recorded predominant frequencies of genotypes D, E and F of C. trachomatis, however, this is insu cient to understand what this infection behaves like in Brazil [28,33].…”

Section: Introductionmentioning

confidence: 99%

“…infection by C. trachomatis, integrated into the National Strategic Plan for STDs and AIDS in Brazil, will have a great positive impact on the public health of Brazilian populations, especially if it is aimed at young adults with sexual experience and who are of reproductive age below 24 years of age, since Brazilian studies on the prevalence of this infection indicate a strong association of C. trachomatis in young people in this age group-age. This will contribute to the identi cation of asymptomatic cases, which will lead to the formulation of prevention strategies to control and reduce recurrent reproductive harm, such as PID, spontaneous abortion and permanent infertility[23][24][25][26][27][28][29][30][31][32][33][34] 56]. Sexual infection by C. trachomatis is a major concern for public health services worldwide.…”

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confidence: 99%

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High prevalence and circulant genotypes of Chlamydia trachomatis in vulnerable university women from four cities in the Brazilian Amazon

Santos

Vieira

Silva

et al. 2022

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Background Approximately 80% of infected women infected by Chlamydia trachomatis are asymptomatic, although this infection can lead to serious complications in the female reproductive tract. Few data on Chlamydiainfection and genotypes are available in Amazonian communities. Objectives To describe the prevalence of and associated factors and to identify the genotypes of sexual C. trachomatis infection in female university students in different urban centers (capital and interiors) in the Brazilian state of Pará, in the eastern Amazon region. Methods A cross-sectional study was performed among young women attending public universities in four different urban centers in the eastern Amazon region. They were invited to participate in the studt and cervical secretions were collected for molecular diagnosis of C. trachomatis. We utilized amplification of the ompA gene by nested PCR. Positive samples were genotyped by nucleotide sequencing. Study participants completed a questionnaire on social, epidemiological, and reproductive health variables. A Qui-square and Binominal regression test were used to evaluate the degree of association of these variables with the infection. Results A total of 686 female students was included in the study. The overall prevalence of C. trachomatis was 11.2% (77/686). The prevalence of this infection was higher in interiors (15.2% vs 9.5%/ p: 0.0443). Female university students who do not have a sexual partner (11.8%/p <0.008), who do not use a condom in their sexual relations (17.8%/p <0.0001) and who reported having suffered a miscarriage (32%/p <0.0001) have high chances of acquiring this sexual infection. The ompA gene was sequenced in only 33 (42.8%) samples, revealing the genotype J was the most frequent (27.2% [9/33]), followed by genotypes D (24.2% [8/33]), and then genotypes F (18.2% [6/33]), E (15.1% [5/33]) K (6.1% [2/33]), Ia (6.1% [2/33]), and G (3.1% [1/33]). Conclusions The high prevalence of sexual infection by C. trachomatis in the female university students from the interior of the state of Pará, individuals with no fixed sexual partner, those that had had a miscarriage, the students that do not use condoms in their sexual relations. The genotype J of C. trachomatis genotypes was the most frequent. These data are important to help defining the epidemiological effects of chlamydial infections in Amazonian populations.

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Section: Discussionmentioning

confidence: 73%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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High prevalence and circulant genotypes of Chlamydia trachomatis in vulnerable university women from four cities in the Brazilian Amazon

Santos

Vieira

Silva

et al. 2022

Preprint

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“…Adicionalmente, estudios de otros países en población general han reportado prevalencias más bajas. Así, en Guinea Bissau, en 500 personas con edades entre 16 y 49 años, fue del 0,8 % [20]; en 210 mujeres de una universidad de Brasil, del 1,9 % [21], y en 2608 sujetos de una zona rural del suroeste China, fue del 1,2 % [22].…”

Section: Discussionunclassified

Prevalencia de infección por Treponema pallidum en individuos atendidos en un centro especializado de Medellín, Colombia

Cardona‐Arias

Higuita-Gutiérrez

Cataño-Correa

2022

Rev. Fac. Nac. Salud Pública

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Objetivo: Describir la prevalencia de infección por Treponema pallidum en individuos atendidos en un centro especializado de Medellín, Colombia, 2019. Metodología: Estudio de corte, con 776 sujetos de población general (aparentemente sanos-asintomáticos y sin factores de riesgo para sífilis), 126 hombres que tienen sexo con hombres (hsh) y 190 jóvenes vulnerables (estrato socioeconómico bajo, desempleados y sin finalizar educación básica), captados intramural y extramuralmente en espacios de concentración de hsh y organizaciones no gubernamentales. Se empleó fuente de información primaria basada en un encuesta y prueba de detección de anticuerpos IgG, IgM e IgA específicos para T. pallidum. Resultados: La prevalencia de infección por T. pallidum fue 0,53 % en jóvenes vulnerables, 2,19 % en población general y 16,67 % en hsh. La razón de odds de infección en los sujetos con edad entre 51-60 años fue 13,8 (IC 95 % = 3,5-51,5) respecto a la hallada en los jóvenes entre 21-30 años; 12,0 (IC 95 % = 1,8-79,2) en quienes no tienen escolaridad frente a los universitarios; 3,3 (IC 95 % = 1,1-9,9) en las personas sin afiliación en salud, comparadas con las del régimen contributivo, y 8,1 (IC 95 % = 2,8-23,0) en quienes tiene relaciones sexuales con grupos clave versus quienes no refieren estas prácticas. Conclusión: Se halló una menor prevalencia de infección por T. pallidum en los jóvenes, seguida de los sujetos de población general y fue mayor en hsh. Se identificaron los grupos de mayor riesgo (entre los tres subgrupos estudiados), que incluyen sujetos excluidos de los programas de prevención, con confluencia de factores de riesgo sexual y privación socioeconómica.

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“…According to the results of this study, BV was found to be related to HPV-51, -52 infections. Previews study in Africa suggested that BV associate with HPV-58 [ 24 ]. Obviously, the epidemiology of HPV and genital tract infection is different in each region, and the founding of this study may guide the HPV vaccine protecting patients with recurrent BV.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of human papillomavirus and bacterial vaginosis among young women in China: a cross-sectional study

et al. 2021

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Background The natural history of human papillomavirus (HPV) is influenced by vaginal microenvironment disorders, such as bacterial vaginosis (BV). The objective of this study was to assess the epidemiology of HPV combined with BV prevalence among Chinese women aged 20–35 years. Methods A total of 2000 sexually active women aged 20–35 years voluntarily enrolled in this study and underwent a ThinPrep cytologic test and PCR-reverse dot blot human papillomavirus genotyping (PCR-RDB HPV test). BV was diagnosed if clue cells were observed (20% more than epithelial cells). Results The overall HPV infection rate in this population was 16.2% (324/2000). Compared with HPV-negative individuals, BV prevalence was higher in the High-risk human papillomavirus (HR-HPV) (5.9% vs. 3.1%, P < 0.001). BV and HPV-51, -52 infection were more commonly associated with each other. In patients with cervical lesions (≥ CIN 1), the BV prevalence rate was higher than in patients with negative for intraepithelial lesion or malignancy (NILM) (11.9% vs. 3.8%, P = 0.002). Conclusion BV was found to be related to HPV-51, -52 infections and cervical lesions. To better manage HPV infected population, more attention should be paid to the prevention and proper treatment of BV.

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High molecular prevalence of HPV and other sexually transmitted infections in a population of asymptomatic women who work or study at a Brazilian university

Abstract: This is an open-access article distributed under the terms of the Creative Commons Attribution License.

Cited by 14 publications

References 30 publications

High prevalence and circulant genotypes of Chlamydia trachomatis in vulnerable university women from four cities in the Brazilian Amazon

High prevalence and circulant genotypes of Chlamydia trachomatis in vulnerable university women from four cities in the Brazilian Amazon

Prevalencia de infección por Treponema pallidum en individuos atendidos en un centro especializado de Medellín, Colombia

The prevalence of human papillomavirus and bacterial vaginosis among young women in China: a cross-sectional study

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