Trypanosoma cruzi vectors in a periurban area of the Western Brazilian Amazon

Moraes, Madson Huilber da Silva; Jesus, Adila Costa de; Madeira, Fernanda Portela; Moresco, Gilberto Gilmar; Oliveira, Jader de; Rosa, João Aristeu da; Camargo, Luís Marcelo Aranha; Bernarde, Paulo Sérgio; Meneguetti, Dionatas Ulises de Oliveira

doi:10.1590/s1678-9946202062087

Cited by 3 publications

(3 citation statements)

References 16 publications

(17 reference statements)

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“…In this study, no significant difference in the infection percentage between the developmental stages of the triatomines and T. cruzi infection was observed. This is unlike the findings of studies by Meneguetti et al (2012) [22], Moraes et al (2020) [38], and Prati et al (2020) [45], where a higher infection rate with trypanosomatids was found in closer-to-adult developmental stages. This difference might be due to the sample size in this study being smaller than that in the cited studies.…”

Section: Discussioncontrasting

confidence: 99%

“…Seventeen triatomines were captured, all belonging to the Rhodnius genus, which is the most commonly found species in palm trees in the Amazon region (Meneguetti et al, 2012) [ 22 ]. These data align with those of other studies conducted in the Alto Juruá region, where the most prevalent genus in palm trees was Rhodnius (Madeira et al, 2020; Moraes et al, 2020; Jesus et al, 2021) [ 11 , 12 , 38 ].…”

Section: Discussionsupporting

confidence: 90%

“…The natural infection rate with T. cruzi was 25% in the Nova Cintra community and 66.67% in the Boca do Moa community, similar to other studies conducted in the Amazon region (Massaro et al, 2008;Meneguetti et al, 2012;Madeira et al, 2020;Moraes et al, 2020;Jesus et al, 2021) [11,12,22,38,44]. In this study, no significant difference in the infection percentage between the developmental stages of the triatomines and T. cruzi infection was observed.…”

Section: Discussionsupporting

confidence: 88%

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Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon

Paixão,

Portela Madeira,

Costa de Jesus

et al. 2024

Pathogens

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Chagas disease (CD) is a typical tropical illness caused by Trypanosoma cruzi. The objective of this study was to assess the prevalence of Chagas disease in communities in two states of the Brazilian Amazon. Data collection occurred in July in the Alto Juruá region of Acre and in December in the communities of Humaitá, Amazonas, in 2019. A total of 477 participants were included in the study. In the communities of Alto Juruá, triatomine collections and analyses of T. cruzi infection were also carried out. All confirmed cases were found in the state of Acre, resulting in a total prevalence of 1.67. Of these eight cases, seven underwent ECG, all of which were concluded as normal by the physician team’s cardiologists. Seventeen triatomine bugs, all belonging to the Rhodnius genus, were captured. The natural infection rate by T. cruzi was 25% in the Nova Cintra community and 66.67% in the Boca do Moa community (Alto Juruá). This research found that more than 1% of the studied population exhibited positive serological results for Chagas disease in the riverine communities during the study period, representing a small portion of cases among those who have not yet been diagnosed.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 88%

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Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon

Paixão,

Portela Madeira,

Costa de Jesus

et al. 2024

Pathogens

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Detection and Genotyping of Trypanosoma cruzi Samples in Species of Genus Rhodnius from Different Environments in the Brazilian Amazon

Bilheiro,

Costa,

Araújo

et al. 2024

Vector-Borne and Zoonotic Diseases

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Trypanosoma cruzi and Trypanosoma rangeli in Acre, Brazilian Amazonia: Coinfection and Notable Genetic Diversity in an Outbreak of Orally Acquired Acute Chagas Disease in a Forest Community, Wild Reservoirs, and Vectors

et al. 2022

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Acute Chagas disease (ACD) caused by Trypanosoma cruzi has emerged as a major food-borne disease in Brazilian Amazonia. For the first time, we characterized an outbreak of orally acquired ACD in Acre, in the forest community of Seringal Miraflores, affecting 13 individuals who shared the pulp of açai palm berries: 11 adults and two children (one newborn), all diagnosed by thick-drop blood smears. The fluorescent fragment length barcoding method, which simultaneously identifies species/genotypes of trypanosomes in blood samples, uncovered an unprecedented genetic diversity in patients from a single outbreak of ACD: T. cruzi TcI in all patients, mostly concomitantly with the non-pathogenic Trypanosoma rangeli of genotypes TrA or TrB, and TcI, TcIV, and TrB in the child. The patients presented persistent fever, asthenia, myalgia, edema of the face and lower limbs, hepatosplenomegaly and, rarely, cardiac arrhythmia. The clinical symptoms were not correlated to gender, age, or to trypanosome species and genotypes. The inferred SSU rRNA phylogenetic analyses of trypanosomes from humans, triatomines and sylvatic hosts included the first sequences of T. cruzi and T. rangeli from humans in southwestern (Acre and Rondônia) Amazonia, and the first TcI/TcIV sequences from Rhodnius spp. from Acre. The sylvatic transmission cycles of genetically different trypanosomes in landscapes changed by deforestation for human settlements and increasing açai production is a novel scenario favoring trypanosome transmission to humans in Acre.

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Trypanosoma cruzi vectors in a periurban area of the Western Brazilian Amazon

Cited by 3 publications

References 16 publications

Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon

Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon

Detection and Genotyping of Trypanosoma cruzi Samples in Species of Genus Rhodnius from Different Environments in the Brazilian Amazon

Trypanosoma cruzi and Trypanosoma rangeli in Acre, Brazilian Amazonia: Coinfection and Notable Genetic Diversity in an Outbreak of Orally Acquired Acute Chagas Disease in a Forest Community, Wild Reservoirs, and Vectors

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