Factors Related to Oral Candidiasis in Elderly Users and Non-Users of Removable Dental Prostheses

Abstract

This study examined the association between oral candidiasis in elderly users and nonusers of prosthesis and its predisposing factors. To this end, we performed a cross-sectional study where saliva samples from 48 patients were collected they used prosthesis and 43 patients (control group) who did not use. Among the 91 patients, Candida spp were isolated in 40 (83.3%) who used prosthesis and in 23 (53.5%) in the control group. A statistically significant association was determined between the two groups, the isolation of yeasts and dental prosthesis (p < 0.05, OR = 4.3). The most common etiological agent was Candida albicans (37 isolates), with 23 (62.2%) in the denture group and 14 (37.8%) (control group). Among patients who presented clinical manifestations of oral candidiasis (n = 24), 83.3% (n = 20) belonged to the group that wore dentures, while only 16.7% (n = 4) belonged to the control group. Elderly patients with diabetes had 4.4 times higher estimated risk of developing oral candidiasis when compared with individuals without this condition. There was no statistically significant association between being user prostheses and have diabetes with the onset of candidiasis. No statistically significant association was determined between xerostomia, use of prosthesis and oral candidiasis. The use of prosthetics and poor oral hygiene in elderly patients predisposes to the development of oral candidiasis.

Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial

“…Regarding the prevalence of species, our findings corroborate studies that showed Candida albicans as the primary etiological agent of denture stomatitis [2, 21, 27, 36, 47–49]. …”

“…Of the 40 patients analyzed, 85% were female. This data corroborates the literature showing a higher prevalence of denture stomatitis among women [8, 21, 27], possibly due to women's increased demand for treatment or greater health care than men, in addition to having a higher life expectancy compared to this group [30, 31]. All 5 male volunteers have been using a prosthesis over 20 years old and slept with the prosthesis.…”

“…species also colonize the irregularities present in the acrylic structure of the dentures [2, 8, 27, 35]. In our study, thirty-eight patients reported sleeping with the dentures, among a total of forty.…”

“…The mouthwash was dispensed in sterile tube and refrigerated until laboratory processing. The collections followed protocol from previous studies [24–27]. …”

Susceptibility to Oral Antiseptics and Virulence Factors Ex Vivo Associated with Candida spp. Isolated from Dental Prostheses

“…Studies have shown that Candida spp. are present in biological material obtained from patients using dental prostheses, and C. albicans has received particular attention because it is more prevalent . However, other Candida species such as C. glabrata , C. parapsilosis (present C. parapsilosis sensu stricto), C. tropicalis , and C. krusei (present Issachenkia orientalis ) have also been reported .…”