Iron supplementation reduces the erosive potential of a cola drink on enamel and dentin in situ

Abstract

Iron has been suggested to reduce the erosive potential of cola drinks in vitro.ObjectiveThe aim of this study was to evaluate in situ the effect of ferrous sulfate supplementation on the inhibition of the erosion caused by a cola drink.Material and MethodsTen adult volunteers participated in a crossover protocol conducted in two phases of 5 days, separated by a washout period of 7 days. In each phase, they wore palatal devices containing two human enamel and two human dentin blocks. The volunteers immersed the devices for 5 min in 150 mL of cola drink (Coca-ColaTM, pH 2.6), containing ferrous sulfate (10 mmol/L) or not (control), 4 times per day. The effect of ferrous sulfate on the inhibition of erosion was evaluated by profilometry (wear). Data were analyzed by paired t tests (p<0.05).ResultsThe mean wear (±se) was significantly reduced in the presence of ferrous sulfate, both for enamel (control: 5.8±1.0 µm; ferrous sulfate: 2.8±0.6 µm) and dentin (control: 4.8±0.8 µm; ferrous sulfate: 1.7±0.7 µm).ConclusionsThe supplementation of cola drinks with ferrous sulfate can be a good alternative for the reduction of their erosive potential. Additional studies should be done to test if lower ferrous sulfate concentrations can also have a protective effect as well as the combination of ferrous sulfate with other ions.

Extrinsic tooth staining potential of high dose and sustained release iron syrups on primary teeth

“…However, it has been shown that exaggerated staining protocols are useful in demonstrating the reduction in staining potential and reduced or absence of staining of teeth in such models can be indicative of low risk of clinical staining [ 26 ]. The potential of iron to stain teeth assumes greater significance in the light of recent research into the effect of iron on dental erosion and studies into the feasibility of incorporating iron into mouth-rinses and aerated beverages [ 27 ]. The fact that a majority of the teeth placed in the solution that combined ferric and ferrous forms of iron is encouraging and must be viewed keeping in mind sporadic pediatric literature that have shown that combination of these two forms of iron can reduce side effects [ 12 , 20 , 28 ].…”

Supplementation of soft drinks with metallic ions reduces dissolution of bovine enamel

“…Their effect was also assessed when combined with iron, since this metal has been reported to reduce the loss of enamel and dentin under erosive challenges caused by soft drinks 10,20 .…”

Calcium phosphate influences erosivity of non alcoholic beverages in vitro

“…Another research group tested metallic ions as additives to soft drinks to prevent erosions. [16,17] They found that ferrous sulfate (human teeth, in situ) as well as combinations of copper, magnesium, manganese, or zinc (bovine tooth powder, in vitro) also show some potential to reduce the erosvity on enamel and dentine. A 7-27% reduction of the dissolution capacity on enamel of two soft drinks was found.…”

“…A 7-27% reduction of the dissolution capacity on enamel of two soft drinks was found. [16,17] To stop the problem of erosion, several authors looked into application of agents with remineralizing potential after substance loss had already occurred. [18,19] [20] Bertoldi et al applied casein phosphopeptide-amorphous calcium phosphate for seven days to eroded extracted teeth and detected partial remineralization.…”