Influence of preventive dental treatment on mutans streptococci counts in patients undergoing head and neck radiotherapy

Meca, Lívia Buzati; Souza, Fátima Regina Nunes de; Tanimoto, Hélio; Castro, Alvimar Lima de; Júnior, Élerson Gaetti-Jardim

doi:10.1590/s1678-77572009000700003

Cited by 13 publications

(17 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Given the high prevalence of mutans Streptococcus spp. in saliva of irradiated patients (Meca et al , ), these observations may have relevance for the development of therapies against biofilm‐dependent infections.…”

Section: Microbiota As Risk Factorsmentioning

confidence: 97%

Microbiota and their role in the pathogenesis of oral mucositis

et al. 2014

View full text Add to dashboard Cite

Oral mucositis in patients undergoing cancer therapy is a significant problem. Its prevalence ranges between 20 and 100%, depending on treatment type and protocols and patient-based variables. Mucositis is self-limiting when uncomplicated by infection. Unfortunately, the incidence of developing a local or systemic infection during the course of the treatment is very high. At this stage, it is unclear which role oral microbiota play in the onset, duration, and severity of oral mucositis. Nevertheless, there is growing interest in this underexplored topic, and new studies are being undertaken to unravel their impact on the pathogenesis of mucositis.

show abstract

Section: Microbiota As Risk Factorsmentioning

confidence: 97%

Microbiota and their role in the pathogenesis of oral mucositis

et al. 2014

View full text Add to dashboard Cite

show abstract

“…The result of pronounced and sometimes persistent xerostomia is the change of oral microbiota, producing a significant increase of oral acidogenic cocci in supragingival biofilm, and a significant elevation in salivary levels of cariogenic cocci, particularly Streptococcus mutans [28][29][30] . This phenomenon is cumulative, usually established after 2000 cGy of radiation, accompanying the severity and persistence of xerostomia 17 .…”

Section: Radiation Caries Oral Streptococci and Mucositismentioning

confidence: 99%

“…This phenomenon is cumulative, usually established after 2000 cGy of radiation, accompanying the severity and persistence of xerostomia 17 . However, the use of sodium fluoride in aqueous solutions or gel minimizes the changes of cariogenic cocci populations, constituting a recognized strategy to prevent the rampant caries associated with RT and xerostomia [30][31][32] . Then, the elevations of cariogenic microorganisms in RT might be understood as result of the absence or precariousness of the preventive measures and the poor hygiene conditions of the patients and their deterioration along RT 33,34 .…”

Section: Radiation Caries Oral Streptococci and Mucositismentioning

confidence: 99%

“…Then, the elevations of cariogenic microorganisms in RT might be understood as result of the absence or precariousness of the preventive measures and the poor hygiene conditions of the patients and their deterioration along RT 33,34 . In radiotherapy centers where preventive dentistry is considered relevant and plays a central role in the prevention of side effects of RT, populations of cariogenic cocci are under partial control 19,30 , consisting transient phenomenon 33,35,36 , and hygiene standards evidences relevant improvement during RT and follow-up period, particularly when intensity modulated radiation therapy is used, which produces less pronounced effects on the salivary glands 19,37 .…”

Section: Radiation Caries Oral Streptococci and Mucositismentioning

confidence: 99%

See 1 more Smart Citation

Oral microbiota and mucositis in patients with head and neck cancer undergoing radiotherapy: literature review

Jardim¹,

Cunha-Correia²,

Okamoto³

et al. 2017

Arch Health Invest

View full text Add to dashboard Cite

Oral microbiota and mucositis in patients with head and neck cancer undergoing radiotherapy: literature review AbstractThe occurrence and severity of mucositis are the main complaints of patients with head and neck cancer submitted to radiotherapy (RT). This condition appears to be associated with changes in the oral microbiota and other side effects of RT, such as xerostomia and candidiasis. The aim of this study was to evaluate the effect of RT on the oral microbiota and its impact on radioinduced mucositis through literature review. Descriptors were selected for the collection of information in different databases, especially SciELO, BIREME, LILACS and PubMed. It was decided to consider only articles published since 1985. The descriptors radiotherapy, mucositis, dental caries, xerostomia, head and neck neoplasms and health promotion were used. It was selected 91 articles specifically discussing the microbiological aspects of mucositis, dental caries, oral candidiasis and microbial effects on the oral health of cancer patients, and 59 were included in the review. It was observed that microbial contamination is a secondary phenomenon capable of exacerbate the inflammation induced by the interaction of the radiation with the oral tissues, aggravating mucositis mainly in patients who present precarious conditions of oral hygiene, which reinforces the role of preventive dentistry in the follow up of the irradiated patient. Descriptors: Radiotherapy; Mucositis; Dental Caries; Xerostomia; Head And Neck Neoplasms; Health Promotion. ResumoA ocorrência e a severidade da mucosite constituem as principais queixas dos pacientes com câncer de cabeça e pescoço submetidos à radioterapia (RT). Essa condição parece estar associada às modificações da microbiota bucal e aos demais efeitos colaterais da RT, como xerostomia e a candidíase. O presente trabalho de revisão da literatura teve como objetivo avaliar o efeito que a RT exerce sobre a microbiota bucal e seu impacto na mucosite radioinduzida através de revisão de literatura. Foram selecionados os descritores para a coleta de informações em diferentes bancos de dados, destacando-se SciELO, BIREME, LILACS e PubMed. Decidiu-se considerar apenas artigos publicados desde 1985. Utilizou-se como descritores os termos radioterapia, mucosite, cárie dentária, xerostomia, neoplasias de cabeça e pescoço e promoção da saúde. Foram selecionados 91 artigos que discutiam especificamente os aspectos microbiológicos da mucosite, cárie dentária, candidíase oral e efeitos microbianos na saúde bucal de pacientes oncológicos e 59 foram incluídos na revisão. Observou-se que a contaminação microbiana é fenômeno secundário capaz de agravar a inflamação induzida pela interação da radiação com os tecidos bucais, agravando-se, principalmente, em pacientes que apresentam condições precárias de higiene bucal, o que reforça o papel da odontologia preventiva no acompanhamento do paciente irradiado. Descritores: Radioterapia; Mucosite; Cárie Dentária; Xerostomia; Neoplasias de Cabeça e Pescoço; Promoção da...

show abstract

“…There is general consensus that patients exposed to radiation to the head and neck need adequate follow‐up to prevent or reduce adverse effects and the need for communication between various caregivers is advocated . It is also important to motivate the patient for subsequent follow‐up, adequate oral hygiene and long‐term use of salivary stimulants/salivary substitutes and fluoride prophylaxis …”

Section: Introductionmentioning

confidence: 99%