In vitro antifungal action of different substances over microwaved-cured acrylic resins

Abstract

Objective:The presence of Candida albicans on the surfaces of denture-base acrylic resins is strongly related to the development of oral stomatitis. This study evaluated the antifungal action of different agents over microwave-cured acrylic resin without polishing specimens previously contaminated with Candida albicans.Material and Methods:Sixty specimens were immersed in BHI broth previously inoculated with the yeast and stored for 3 h at 37°C. They were divided into 5 experimental groups (n=10): G1: 2% chlorhexidine solution (10 min); G2: 0.5% sodium hypochlorite (10 min); G3: modified sodium hypochlorite (10 min); G4: effervescent agent (5 min); G5: hydrogen peroxide 10v (30 min). The specimens of the control group 1 (C1) were not disinfected. Ten additional specimens of the control group 2 (C2) were not infected with the yeast, aiming to check the asepsis during the experiment. The disinfection agents were neutralized and the acrylic resin specimens were immersed in BHI Broth for 24 h. Culture media turbidity was evaluated spectrophotometrically according to the transmittance degree, i.e. the higher the transmittance the stronger the antimicrobial action. Statistical analysis was performed (Kruskal-Wallis Test, p<0.05).Results:The results, represented by the medians, were: G1 = 40; G2 = 100; G3 = 100; G4 = 90; G5 = 100; C1 = 40; C2 = 100.Conclusions:This in vitro study suggested that sodium hypochlorite-based substances and hydrogen peroxide are more efficient disinfectants against C. albicans than 2% chlorhexidine solution and the effervescent agent.

Cytocompatible antifungal acrylic resin containing silver nanoparticles for dentures

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Materiais E Métodos De Controle Do Biofilme Em Próteses Removíveis - Revisão De Literatura

“…As próteses removíveis podem ser higienizadas, a depender do modo de ação, de forma mecânica, cujo método mais comum é a escovação com água e sabão neutro ou dentifrícios; de forma química, onde as próteses são imersas em alguma solução química, ou ainda com associação de ambos os métodos 13 .…”

The Use of Microwave Energy in Dental Prosthesis

“…Bacterial and yeast plaque on dentures may lead to serious infections, such as systemic candidal infection, particularly in patients who have debilitating diseases (Montagner et al, 2009). The use of microwave energy to disinfect dentures has been suggested to overcome the problems associated with denture cleaning.…”