Efficiency of 6- and 12-punctures biopsies to detect prostate cancer in patients with PSA&lt; 10 ng/mL and normal digital rectal examination

Slongo, Luiz Edison; Sugisawa, Mário C.; Ioshii, Sérgio Ossamu; Filho, Renato Tambara; Rocha, Luiz Carlos de Almeida

doi:10.1590/s1677-55382003000100005

Cited by 4 publications

(3 citation statements)

References 13 publications

(12 reference statements)

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“…Generally, in the clinical setting, when a patient is diagnosed as a suspicious prostate cancer sufferer with a high PSA level or an abnormal screening DRE, a biopsy is frequently suggested [56]. Often, when doing a biopsy, the prostate is divided into sections based on the number of biopsy points to use, followed by shooting a needle in each section to extract the respective tissue sample.…”

Section: Experimental Results and Analysismentioning

confidence: 99%

In vivo MRI based prostate cancer localization with random forests and auto-context model

Qian

Wang

Gao

et al. 2016

Computerized Medical Imaging and Graphics

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Prostate cancer is one of the major causes of cancer death for men. Magnetic resonance (MR) imaging is being increasingly used as an important modality to localize prostate cancer. Therefore, localizing prostate cancer in MRI with automated detection methods has become an active area of research. Many methods have been proposed for this task. However, most of previous methods focused on identifying cancer only in the peripheral zone (PZ), or classifying suspicious cancer ROIs into benign tissue and cancer tissue. Few works have been done on developing a fully automatic method for cancer localization in the entire prostate region, including central gland (CG) and transition zone (TZ). In this paper, we propose a novel learning-based multi-source integration framework to directly localize prostate cancer regions from in vivo MRI. We employ random forests to effectively integrate features from multi-source images together for cancer localization. Here, multi-source images include initially the multi-parametric MRIs (i.e., T2, DWI, and dADC) and later also the iteratively-estimated and refined tissue probability map of prostate cancer. Experimental results on 26 real patient data show that our method can accurately localize cancerous sections. The higher section-based evaluation (SBE), combined with the ROC analysis result of individual patients, shows that the proposed method is promising for in vivo MRI based prostate cancer localization, which can be used for guiding prostate biopsy, targeting the tumor in focal therapy planning, triage and follow-up of patients with active surveillance, as well as the decision making in treatment selection. The common ROC analysis with the AUC value of 0.832 and also the ROI-based ROC analysis with the AUC value of 0.883 both illustrate the effectiveness of our proposed method.

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Section: Experimental Results and Analysismentioning

confidence: 99%

In vivo MRI based prostate cancer localization with random forests and auto-context model

Qian

Wang

Gao

et al. 2016

Computerized Medical Imaging and Graphics

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“…28.02.4779 in different countries. 5,6,7 However, far from a standardized practice, prostate biopsy is still evolving. Indeed.…”

Section: Introductionmentioning

confidence: 99%

Frequency of detection of carcinoma of prostate by TRUS guided core biopsy in patients with PSA level of 4 to 10 ng/ml: A comparison of eight verses fourteen core biopsies.

Chaudhry

Farooq

Mehboob³

et al. 2021

TPMJ

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Objective: To compare the frequency of detection of prostatic carcinoma in patients with prostatic specific antigen level of 4 to 10ng/ml by TRUS guided eight versus fourteen core biopsies in a tertiary care hospital. Study Design: Interventional Comparative study (Randomized Control Trial). Setting: Department of Urology, Jinnah Hospital, and Lahore. Period: January, 2014 to February, 2019. Material & Methods: 340 patients included in the study, according to inclusion criteria, were divided in two groups of 170 patients each. Eight core biopsies were taken in one group and 14 core biopsies were taken in other group by single radiologist to diagnose carcinoma of prostate. Prostatic carcinoma was labeled when pathologist find atypical cells or anaplasia in the biopsy tissues under microscope. Results: Carcinoma of prostate was detected in 123 (36%) patients while rest 217 (64%) showed negative result on histopathology examination. Age of patients in both groups ranged from 40 to 62 years with mean 49.32+5.464 years. The CoP was detected in 55 out of 179 patients younger than 50 years and 68 out of 161 patients older than 50 years. Amongst the 123 patients having been detected CoP, 82 (67%) patients has PSA values ranging 6 to 10 ng/ml while just 41 (33%) has value of 4 to 5 ng/ml. The frequency of detection of CoP among patients having PSA values ranging from 4 to 10ng/ml. by TRUS guided eight core biopsy and fourteen core biopsy group is 17.35% and 18.82% respectively. Conclusion: There is no difference in the frequency of detection of CoP by TRUS guided fourteen core biopsy and eight core biopsy techniques.

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“…The common protocol used in TRUS guided prostate biopsy is sextant biopsy proposed by Hodge et al in the late eighties ( 16 , 17 ). However in the last decade, several studies were designed to evaluate prostate cancer detecting performance by TRUS guided prostate biopsy with more than six biopsies either from other sites of prostate or repeating biopsy in the six previous areas ( 18 - 21 ). The results of studies confirmed the hypothesis that greater numbers of biopsies increases the diagnostic power.…”

Section: Introductionmentioning

confidence: 99%

Prostate Biopsy Using Transrectal Ultrasonography; The Optimal Number of Cores Regarding Cancer Detection Rate and Complications

Ghafoori¹,

Velayati

Ghasabeh

et al. 2015

Iran J Radiol

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Background:Transrectal ultrasound guided biopsy of the prostate is the most common modality used to diagnose prostate cancer.Objectives:The aim of this study was to evaluate the optimal number of cores at prostate biopsy, which have the most diagnostic value with least adverse effects.Patients and Materials:Transrectal ultrasonography (TRUS) guided biopsy was performed in 180 patients suspicious for prostate cancer due to either abnormal rectal examination or elevated PSA. The patients were divided randomly into three groups of six-core, twelve-core and eighteen-core biopsies. The detection rate of prostate cancer in each group with the rate of post biopsy urinary infection and prostatitis were compared.Results:Prostate cancer was diagnosed in 8 (13.3%), 21 (35%) and 24 (40%) patients in six, twelve and eighteen core biopsy groups, respectively. Urinary tract infection and prostatitis occurred in 17 (28.3%), 23 (38.3%) and 35 (58.3%) patients in six, twelve and eighteen core biopsy groups, respectively. Considering the detection rate of prostate cancer, there was a significant difference between 6 and 12 core biopsy groups (P = 0.006) and 12-core biopsies detected more cases of prostate cancer, but there was no significant difference between 12 and 18 core biopsy groups (P = 0.572). Considering the infection rate, there was no significant difference between 6 and 12 core biopsy groups (P = 0.254), but there was a significant difference between 12 and 18 core biopsy groups (P = 0.028) and infectious complications occurred more frequently in 18-core biopsy group.Conclusions:The best balance between detection rate of prostate cancer and infectious complications of biopsies achieved in twelve-core biopsy protocol. Twelve-core biopsy enhances the rate of prostate cancer detection with minimum adverse effects.

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Efficiency of 6- and 12-punctures biopsies to detect prostate cancer in patients with PSA< 10 ng/mL and normal digital rectal examination

Cited by 4 publications

References 13 publications

In vivo MRI based prostate cancer localization with random forests and auto-context model

In vivo MRI based prostate cancer localization with random forests and auto-context model

Frequency of detection of carcinoma of prostate by TRUS guided core biopsy in patients with PSA level of 4 to 10 ng/ml: A comparison of eight verses fourteen core biopsies.

Prostate Biopsy Using Transrectal Ultrasonography; The Optimal Number of Cores Regarding Cancer Detection Rate and Complications

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