Malnutrition and experimental epilepsy

Gomes, Tâmara Kelly de Castro; Oliveira, Suzana Lima de; Castro, Raul Manhães de

doi:10.1590/s1676-26492011000100006

Cited by 3 publications

(1 citation statement)

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“…Early life nutritional programming is based on the observation that nutritional and environmental changes, or lack thereof, can reset the developmental path during a critical period of life, when tissues still have plasticity and are in a higher proliferating state and differentiating phase (de Moura et al, 2008;Gomes et al, 2011). Research has demonstrated that nutritional programming can occur via epigenetics and can take place as early as late gestation (Moisa et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Invited Review: Nutritional regulation of gut function in dairy calves: From colostrum to weaning

Fischer

Villot

Niekerk

et al. 2019

Applied Animal Science

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publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. ABSTRACTPurpose: Published literature regarding calf nutrition was reviewed to create an information base for the implementation of proper nutritional management to maximize health and productivity.Sources: The main source of data and information for this review was peer-reviewed literature.Synthesis: Feeding a sufficient volume of colostrum during the first hours of life is crucial to calf health and survival; however, less is known about transition milk feeding and the potential benefits of the myriad of bioactive compounds it contains. After feeding colostrum and transition milk, calves are susceptible to diarrhea when moved onto high amounts of milk, and antibiotic use is often necessary to decrease disease. Feeding an elevated plane of milk nutrition results in increased ADG and, in some studies, increased future milk production. Thus, this nutritional strategy is recommended; however, weaning calves from high volumes of milk represents massive changes in the structure and microbiology of the gastrointestinal tract.Conclusions and Applications: Colostrum and transition milk contain an abundance of bioactive molecules that can positively affect gut development and microbiota. There is significant potential for the use of novel feeding strategies and microbial-based products as alternatives to antibiotics. Calves fed an elevated plane of nutrition in the first month of life have greater productivity and growth. However, weaning should take place later in life. Moreover, applying a proper step-down feeding protocol is recommended, as it allows calves to intake and digest sufficient solid feed for growth and minimize distress at weaning.

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Section: Introductionmentioning

confidence: 99%