Patologia do transplante renal: achados morfológicos principais e como laudar as biópsias

Sementilli, Ângelo; David, Débora Leite; Malheiros, Denise Maria Avancini Costa; Visoná, Iria; Pêgas, Karla Laís; Franco, Marcello; Soares, Maria Fernanda; Edelweiss, Maria Isabel Albano; Caldas, Maria Lúcia Ribeiro; Araújo, Sérgio de

doi:10.1590/s1676-24442008000400010

Cited by 8 publications

(7 citation statements)

References 62 publications

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“…Renal transplantation was introduced as a large‐scale substitutive therapy from the 1960s, reaching significant growth in the 1980s and is widely performed worldwide, among solid organ transplants . Even though most renal transplantation has satisfactory results, numerous risk factors are associated with the posttransplantation period, such as graft rejection, which states the need for permanent immunosuppressive therapy …”

Section: Introductionmentioning

confidence: 99%

Prevalence of rotavirus and human bocavirus in immunosuppressed individuals after renal transplantation in the Northern Region of Brazil

Castro¹,

Calvet

Sousa

et al. 2019

Journal of Medical Virology

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Immunosuppressive therapy causes severe impairment of host defense and diarrhea is a frequent complication in renal transplant recipients. This study aimed to describe the occurrence of Rotavirus A (RVA) and Human Bocavirus (HBoV) in fecal samples of immunosuppressed patients submitted to renal transplantation during posttransplant follow‐up. A longitudinal study was carried out involving a 25‐patient cohort, selected for kidney transplantation. A total of 126 fecal samples were collected between May 2014 and May 2016. Molecular techniques were used to detect and characterize circulating RVA and HBoV genotypes and statistical analysis were applied to verify the association between epidemiological and clinical characteristics. The prevalence of RVA and HBoV was 24% (6/25) and 40% (10/25), respectively. Among RVA and HBoV positive cases, the majority was female; did not conduct water treatment nor had adequate sewage facilities. The most detected genotypes were RVA G3 (62.5%) and HBoV‐3 (95%). Phylogenetic analysis of HBoV strains indicated that studied samples were similar to those found in Asian and American countries. The present study point out the circulation of these viral agents among immunosuppressed individuals and these findings will enable the construction of new knowledge and care perspectives on the cause of diarrhea in this population.

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Section: Introductionmentioning

confidence: 99%

Prevalence of rotavirus and human bocavirus in immunosuppressed individuals after renal transplantation in the Northern Region of Brazil

Castro¹,

Calvet

Sousa

et al. 2019

Journal of Medical Virology

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“…Kidney transplantation was introduced as large scale replacement therapy in the 1960s, achieving significant growth in the 1980s (1) . The introduction of new immunosuppressive agents provided significant reduction in the incidence of acute rejection (AR) (1) .…”

Section: Introductionmentioning

confidence: 99%

“…The introduction of new immunosuppressive agents provided significant reduction in the incidence of acute rejection (AR) (1) . As criteria for kidney transplantation, we considered: medical, surgical and psychosocial assessment of the patient.…”

Section: Introductionmentioning

confidence: 99%

“…As criteria for kidney transplantation, we considered: medical, surgical and psychosocial assessment of the patient. Exams and assessment of compatibility with the potential donor (HLA-Human Leukocyte Antigens) (1)(2)(3) . Absolute and relative contraindications for patient transplantation are: active infection, low survival prognosis, severe psychiatric problems, uncontrolled psychosis, addiction, heart disease, active hepatitis and possible nonadherence to treatment.…”

Section: Introductionmentioning

confidence: 99%

“…Absolute and relative contraindications for patient transplantation are: active infection, low survival prognosis, severe psychiatric problems, uncontrolled psychosis, addiction, heart disease, active hepatitis and possible nonadherence to treatment. It is not included among the contraindications: advanced age, and previous transplants (1)(2) . In the year 2014, according to the Brazilian Society of Nephrology, the number of people with kidney disease, in Brazil, was on the order of 54.000, it was estimated that 48,198 required hemodialysis and only 6.2% of patients with chronic renal failure were submitted to kidney transplantation.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of infection in kidney transplantation from living versus deceased donor: systematic review and meta-analysis

Taminato

Fram

Grothe

et al. 2015

Rev. esc. enferm. USP

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Objective: To verify if the type of donor is a risk factor for infection in kidney transplant recipients. Methods: Systematic Review of Literature with Meta-analysis with searches conducted in the databases MEDLINE, LILACS, Embase, Cochrane, Web of Science, SciELO and CINAHL. Results: We selected 198 studies and included four observational studies describing infections among patients distinguishing the type of donor. Through meta-analysis, it was shown that in patients undergoing deceased donor transplant, the outcome infection was 2.65 higher, than those who received an organ from a living donor. Conclusion:The study showed that deceased kidney donor recipients are at an increased risk for developing infections and so the need for establishing and enforcing protocols from proper management of ischemic time to the prevention and control of infection in this population emerges. Prevalence of infection in kidney transplantation from living versus deceased donor: systematic review and meta-analysis Prevalência de infecção em transplante renal de doador vivo versus falecido: revisão sistemática e metanálise Prevalencia de infección en trasplante renal de donante vivo versus fallecido: revisión sistemática y metanálisis

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Cystatin C and inflammatory markers in kidney transplant recipients

Lima¹,

Salgado²,

Ferreira³

et al. 2011

Revista da Associação Médica Brasileira

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Patologia do transplante renal: achados morfológicos principais e como laudar as biópsias

Abstract: Os autores são membros do Clube do Rim, da Sociedade Brasileira de Patologia (SBP). artigo de reVisão review article

Cited by 8 publications

References 62 publications

Prevalence of rotavirus and human bocavirus in immunosuppressed individuals after renal transplantation in the Northern Region of Brazil

Prevalence of rotavirus and human bocavirus in immunosuppressed individuals after renal transplantation in the Northern Region of Brazil

Prevalence of infection in kidney transplantation from living versus deceased donor: systematic review and meta-analysis

Cystatin C and inflammatory markers in kidney transplant recipients

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