Pró-calcitonina e proteína C reativa em processos infecciosos graves

Andriolo, Adagmar; Costa, Roberta Pasianotto; Novo, Neil Ferreira

doi:10.1590/s1676-24442004000300007

Cited by 4 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Regarding the evaluation of the C-reactive protein, which has an intense serum elevation after assaults on the body, being used as a sensitive marker for infectious and inflammatory processes [22], Vaz et al [23] reported that despite controversy in the literature, this test is a reliable indicator of infections in newborns. However, one believes that this form of assessment was ineffective in the present study, according to what was previously stated.…”

Section: Discussionmentioning

confidence: 99%

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

et al. 2013

View full text Add to dashboard Cite

The effectiveness of low-level laser therapy (LLLT) in the presence of an infectious process has not been well elucidated. The aim of the study was to evaluate the effects of LLLT in an experimental model of septic arthritis. Methods. Twenty-one Wistar rats were divided as follows: control group, no bacteria; placebo group, bacteria were inoculated; Treated group, bacteria were injected and treatment with LLLTwas performed. To assess nociception, a von Frey digital analgesimeter was applied. Synovial fluid was streaked to analyze bacterial growth. The standard strain of S. aureus was inoculated in the right knee. LLLT was performed with 660 nm, 2 J/cm2, over 10 days. After treatment, the knees were fixed and processed for morphological analysis by light microscopy. Results. It was found that nociception increases in the right knee. There was a lack of results for the seeding of the synovial fluid. The morphological analysis showed slight recovery areas in the articular cartilage and synovia; however, there was the maintenance of the inflammatory infiltrate. Conclusion. The parameters used were not effective in the nociception reduction, even with the slight tissue recovery due to the maintenance of inflammatory infiltrate, but produced no change in the natural history of resolution of the infectious process.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Os níveis de procalcitonina não aumentam tão rapidamente quanto os níveis de IL-6 ou IL-8. Níveis altos de procalcitonina são detectados em 4 a 6 horas após uma provocação de resposta sistêmica com endotoxina ou outros estímulos sépticos (17,18) .…”

Section: Neutropenia Febrilunclassified

Avaliação do tempo de enchimento capilar como marcador de gravidade em pacientes neutropênicos febris

Ponte¹

View full text Add to dashboard Cite

The mortality associated with febrile neutropenia can reach levels above 50%. Fever occurs frequently during chemotherapy to induce neutropenia: more than 80% of patients with hematologic malignancy present febrile neutropenia at least one or more chemotherapy cycles, this percentage decreases to solid tumors. Patients with febrile neutropenia characterized by the paucity of symptoms. Fever has sensitivity and specificity to detect infection uncertain. We need to identify clinical signs of occult hypoperfusion before the blood pressure drops. O capillary refill time has been used for decades in medicine to assess a critical patient. A critically ill patient is unlikely to have a time of less than three seconds capillary refill, but and patient with normal pressure, capillary refill time would be able to predict severity. Action research study aimed to establish if the capillary refill time can predict the severity of the febrile, neutropenic septic patients. The capillary refill time was studied in 50 patients with febrile neutropenia after chemotherapy received at the emergency department of the University Hospital of Brasilia. Included were all with a minimum mean arterial pressure of 75 mmHg, saturation ratio o2 / FiO 2> 300 and a Glasgow Coma Scale of 15. Os Inclusion criteria were at least three SIRS criteria, suspected infection and neutropenia after chemotherapy. The capillary refill time was calculated from the pressure on the patient's right index finger for 15 seconds and then timed the return time to the initial color. We studied whether there is a relationship between the value found in the TEC and clinical outcomes. The main clinical outcomes were chosen scaling antibiotic, length of hospitalization, positive cultures and neutrophil counts. The gold standard for gravitaty was the level and score sofa (sepsis-related organ failure assessment). The capillary refill time greater than or equal to three seconds was effective for predicting poor clinical outcome since it showed p <0.05 compared to longer hospitalization, p <0.01 relative to antibiotic escalation, p <0.01 compared to positive blood cultures and p <0.01 compared to neutrophil numbers.

show abstract

“…A extensão das concentrações dinâmicas da PCT é bem mais ampla (de < 0,5 até níveis acima de 500 ng/mL) do que a PCR (Reinhart, 2001). Em particular durante os estágios mais avançados da infecção, a PCR falha em não apresentar um aumento posterior, enquanto que os aumentos da PCT refletem a gravidade da SIRS (Meisner et al, 1999d;Andriolo et al, 2004). O diagnóstico de sepse grave, e assim da disfunção orgânica, correlaciona-se fortemente com um incremento significativo das concentrações de PCT (de Werra et al, 1997;Al-Nawas e Shah, 1996).…”

Section: Avaliação Da Gravidade Da Sepse E Inflamação Sistêmicaunclassified

Procalcitonina (PCT) como indicador de infecção grave em adultos neutropênicos febris

Massaro¹

View full text Add to dashboard Cite

Pró-calcitonina e proteína C reativa em processos infecciosos graves

Cited by 4 publications

References 0 publications

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis

Avaliação do tempo de enchimento capilar como marcador de gravidade em pacientes neutropênicos febris

Procalcitonina (PCT) como indicador de infecção grave em adultos neutropênicos febris

Contact Info

Product

Resources

About