Avaliação do exercício físico como fator de analgesia em um modelo experimental de ciatalgia

Gaffuri, Juliana; Meireles, Anamaria; Rocha, Bruno Pogorzelski; Rosa, Camila Thieime; Artifon, Elisangela Lourdes; Silva, Lígia Inez; Moreira, Natália Boneti; Bertolini, Gladson Ricardo Flor

doi:10.1590/s1517-86922011000200009

Cited by 9 publications

(7 citation statements)

References 22 publications

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“…On the third post-operative day (Gaffuri et al, 2011) the animals in G2 and G4 were submitted to resistance exercise (climbing steps) five days a week, with an interval of two days, totalling 21 days of treatment (Gorio, Carmignotto, Finesso, Polato, & Nunzi, 1983). The exercise was conducted in two series of 10 consecutive ascents of the ladder, with an additional weight of 100g and with an interval of 60 seconds between sets for rest.…”

Section: Methodsmentioning

confidence: 99%

Resistance exercise recovery morphology and AQP1 expression in denervated soleus muscle of Wistar rats

Lovison¹,

Vieira²,

Kunz³

et al. 2018

motricidade

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It was our objective to analyse the effects of resistance exercise (climbing steps), which was started in the acute phase, on the histomorphometry and the expression of aquaporin 1 (AQP1) in the soleus muscle after sciatic nerve injury in Wistar rats. Twenty-four adult rats were randomly divided into the following four groups, containing six animals each: control (G1); exercise (G2); injury (G3); and exercise with injury (G4). Three days after the compression of the sciatic nerve, the animals in G2 and G4 were submitted to resistance exercise for 21 non-consecutives days. The exercise was conducted in two series of 10 consecutive ascents of the ladder, with an additional weight of 100g and with an interval of 60 seconds between sets for rest. After this period, the animals were sacrificed, and the soleus muscle was processed. The number of blood capillaries in G3 was 65.7% and 76.86% higher when compared with the G2 and G4, respectively. The morphological analysis revealed muscle damage in G3, hypertrophy in G2 and significant improvement in the muscle in G4. The AQP1 was immunolocalized in the endothelium of blood capillaries present in the muscle fibres, with different expressions in the groups. Resistance exercise initiated in the acute phase was an effective therapeutic modality in the recovery of morphological aspects in the soleus muscle after denervation.

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Section: Methodsmentioning

confidence: 99%

Resistance exercise recovery morphology and AQP1 expression in denervated soleus muscle of Wistar rats

Lovison¹,

Vieira²,

Kunz³

et al. 2018

motricidade

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“…During the remaining 8 days of remobilization, on alternate days, a progression in terms of time and series of exercises was performed; swimming time was 40 min and jumps were performed in four sets of 10 jumps, with 1 min of rest between sets. The swimming exercises were performed in groups of 3 animals per time and without any additional weight, while the jumping exercises in water were conducted individually and with an additional 50% of body weight, according to model adjustments described by Gaffuri et al (22). …”

Section: Methodsmentioning

confidence: 99%

Effects of immobilization and remobilization on the ankle joint in Wistar rats

Kunz

Coradini

Silva

et al. 2014

Braz J Med Biol Res

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A sprained ankle is a common musculoskeletal sports injury and it is often treated by immobilization of the joint. Despite the beneficial effects of this therapeutic measure, the high prevalence of residual symptoms affects the quality of life, and remobilization of the joint can reverse this situation. The aim of this study was to analyze the effects of immobilization and remobilization on the ankle joint of Wistar rats. Eighteen male rats had their right hindlimb immobilized for 15 days, and were divided into the following groups: G1, immobilized; G2, remobilized freely for 14 days; and G3, remobilized by swimming and jumping in water for 14 days, performed on alternate days, with progression of time and a series of exercises. The contralateral limb was the control. After the experimental period, the ankle joints were processed for microscopic analysis. Histomorphometry did not show any significant differences between the control and immobilized/remobilized groups and members, in terms of number of chondrocytes and thickness of the articular cartilage of the tibia and talus. Morphological analysis of animals from G1 showed significant degenerative lesions in the talus, such as exposure of the subchondral bone, flocculation, and cracks between the anterior and mid-regions of the articular cartilage and the synovial membrane. Remobilization by therapeutic exercise in water led to recovery in the articular cartilage and synovial membrane of the ankle joint when compared with free remobilization, and it was shown to be an effective therapeutic measure in the recovery of the ankle joint.

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“…Therefore, the animal was kept in high wooden box, with screen floor and the filament positioned at 90 degrees with the animal's paw; pressure was applied with gradual increase in this region, until the animal withdraws its limb, by noting then the value of the withdrawal threshold indicated by the apparatus. To facilitate the adaptation of animals to this instrument in the three days prior to the injury, the simulation was carried out for this evaluation [15]. …”

Section: Methodsmentioning

confidence: 99%

Nociceptive and Neuronal Evaluation of the Sciatic Nerve of Wistar Rats Subjected to Compression Injury and Treated with Resistive Exercise

Antunes

Lovison

Karvat

et al. 2016

Pain Research and Management

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Background. To investigate the climb stairs resistance exercise on nociception and axonal regeneration in the sciatic nerve of rats. Methods. 24 Wistar rats were divided: control group (CG—no injury), exercise group (EG—no injury with physical exercise), lesion group (LG—injury, but without exercise), and treated group (LEG—injury and physical exercise). LG and LEG were subjected to sciatic nerve compression with hemostat. From the 3rd day after injury began treatment with exercise, and after 22 days occurs the removal of a nerve fragment for morphological analysis. Results. Regarding allodynia, CG obtained values less than EG (p = 0.012) and larger than LG and LEG (p < 0.001). Histological results showed that CG and EG had normal appearance, as LG and LEG showed up with large amounts of inflammatory infiltration, degeneration and disruption of nerve fibers, and reduction of the myelin sheath; however LEG presented some regenerated fibers. From the morphometric data there were significant differences, for nerve fiber diameter, comparing CG with LG and LEG and comparing axon diameter and the thickness of the myelin of the CG to others. Conclusion. Climb stairs resistance exercise was not effective to speed up the regenerative process of axons.

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Avaliação do exercício físico como fator de analgesia em um modelo experimental de ciatalgia

Cited by 9 publications

References 22 publications

Resistance exercise recovery morphology and AQP1 expression in denervated soleus muscle of Wistar rats

Resistance exercise recovery morphology and AQP1 expression in denervated soleus muscle of Wistar rats

Effects of immobilization and remobilization on the ankle joint in Wistar rats

Nociceptive and Neuronal Evaluation of the Sciatic Nerve of Wistar Rats Subjected to Compression Injury and Treated with Resistive Exercise

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