2007
DOI: 10.1590/s1517-86922007000500013
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Terapia gênica, doping genético e esporte: fundamentação e implicações para o futuro

Abstract: Optimal performance has been constantly sought for in high level competitive sport. To achieve this goal, many athletes use illicit drugs and methods, which could have important side effects. Gene therapy is a very recent therapeutic modality, whose results have shown to be efficient in the treatment of severe diseases so far.

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Cited by 16 publications
(17 citation statements)
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References 44 publications
(104 reference statements)
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“…Artioli at al. 16 discuss genetic doping, which should be initiated in the academic and sports fields, in order to study prevention, control and detection measures of gene doping, thus avoiding future problems regarding the misuse of this promising therapy. Menon et al 17 compared weight and length adaptations of the soleus muscle in rats, besides the total estimate of the sarcomeres in series, when submitted to intermittent stretching during immobilization in plantarflexion.…”
Section: Discussionmentioning
confidence: 99%
“…Artioli at al. 16 discuss genetic doping, which should be initiated in the academic and sports fields, in order to study prevention, control and detection measures of gene doping, thus avoiding future problems regarding the misuse of this promising therapy. Menon et al 17 compared weight and length adaptations of the soleus muscle in rats, besides the total estimate of the sarcomeres in series, when submitted to intermittent stretching during immobilization in plantarflexion.…”
Section: Discussionmentioning
confidence: 99%
“…The second way to approach sports doping as an ethical issue is to consider sports ethics as representing a separate entity from medical ethics. In other words, sport is seen as a moral practice which, while not requiring a rejection of the concepts of medical ethics, depends more on the sporting context than on the medical context (59,60).…”
Section: Bioethics Of Gene Dopingmentioning
confidence: 99%
“…Desde então, com a identificação de cada gene e suas respectivas proteínas responsáveis por determinada atividade no corpo humano, entre elas, a eritropoetina (resistência), bloqueadores de miostatina (crescimento da musculatura), IGF-1 e GH (força), leptina (perda de peso), VEGF (energia), endorfinas e encefalinas (analgésicos) e PPAR-(resistência) (Artioli, Hirata & Lancha, 2007), a dopagem com o recurso da biologia molecular e da genética passaram a ser alvo dos órgãos antidoping, como a WADA (World Anti-Doping Agency).…”
Section: Introductionunclassified