The neem [Azadirachta indica a: juss (meliaceae)] oil reduction in the in vitro production of zearalenone by Fusarium graminearum

Geraldo, Márcia Regina Ferreira; Costa, Christiane Luciana da; Arrotéia, Carla Cristina; Kemmelmeier, Carlos

doi:10.1590/s1517-83822011000200036

Cited by 5 publications

(3 citation statements)

References 19 publications

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“…Neem oil extract inhibits zearalenone production at 0.1-0.5% concentrations, but the highest inhibition (59.05%) of mycotoxin synthesis occurred at 0.1%. 49 The aqueous preparation of Neem leaves is found to be effective in activating immune responses against tumor antigens. Studies in experimental stages have shown that the extract, in combination with a breast tumor-associated antigen, was effective in initiating a strong IgG response as compared to the response generated by the breast cancerassociated antigen alone.…”

Section: Medicinal Usesmentioning

confidence: 99%

Biological Detail and Therapeutic Effect of Azadirachta Indica (Neem Tree) Products- A Review

Ahmad¹,

Maqbool²,

Srivastava³

et al. 2019

jebmh

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BACKGROUND The Neem tree (Azadirachta indica) growing in tropical and subtropical regions, is a native tree of India. Neem belongs to Meliaceae family, also known as a Limbo, Nim, Nimba, Medusa and Vempu. It is also called "village pharmacy" of South Asia because of its enormous medicinal properties. Every part of Neem is so useful for the treatment of human disease. Various parts of the tree are well known for their medicinal properties which are prescribed by Ayurvedic, Siddha, and herbal medicine practitioners in India. Currently Azadirachta indica-Neem formulations are effective against a several diseases, ulcers, eczema, sores, burns, ulcers etc. It has been used in ayurvedic medicines for thousands of years because it exhibits therapeutic properties such as anti-viral, anti-fungal, anti-insecticidal, anti-bacterial, anti-allergic, anti-helminthic, anti-inflammatory and anti-dermatic properties. Approximately 135 different structural compounds have been identified from different parts of Neem tree for their beneficial effects.

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Section: Medicinal Usesmentioning

confidence: 99%

Biological Detail and Therapeutic Effect of Azadirachta Indica (Neem Tree) Products- A Review

Ahmad¹,

Maqbool²,

Srivastava³

et al. 2019

jebmh

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show abstract

“…Neem oil extract decreases zearalenone production at 0.1-0.5% concentrations, but the highest inhibition (59.05%) of mycotoxin synthesis occurred at 0.1% (Geraldo et al, 2011). Several species of Fusarium produce mycotoxins such as trichothecenes and zearalenone in cereal crops that are used as animal and poultry feed and can affect human and animal health if they enter the food chain.…”

Section: Efficacymentioning

confidence: 99%

Neem Extract

Kumar¹,

Rahal²,

Malik³

2016

Nutraceuticals

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“…Azadirachta indica also known as Margosa, neem or Indian lilac is a tree belonging to family Maliaceae. Leaf extract of margosa has been demonstrated to have antifungal action against a variety of fungi, and under the right circumstances, it is said to detoxify mycotoxins produced by FFSC complex (Mishra et al 1994;Mossini et al 2009;Geraldo et al 2011). Quercetin, a avonoid that differs from nimbosterol (β-sitosterol), and several limonoids, including Nimbin, are abundant in margosa leaves (Chen et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Seed coating with novel sodium alumino silicate margosa composite – A proficient technique to reduce mycotoxins of Fusarium fujikuroi species complex inciting discoloration of rice

SINGH,

Sharma,

Mandal

et al. 2024

Preprint

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Infestation of fungi during storage of grains causes about 4.6–6% wastage of cereal grains. Among other fungi Fusarium fujikuroi speciescomplex (FFSC) is one of the major causes of grain discoloration of rice. Due to the negative impacts of toxicgenic FFSC complex on seed health and quality metrics, it significantly reduces the market value of rice seeds. Apart from nutrient losses to rice seeds toxic fungal metabolites like fumonisin B1, fumonisin B2, fusaric acid, and gibberellic acid produced by FFSC complex interacts with physiological parameters influencing the integrity of seeds during storage. Due to the detrimental effects on seed germination and vitality, chemical seed treatments are usually avoided while the seeds are in storage. This paper presents the efficacy of novel sodium alumino silicate (SAS)-Margosa composite against toxigenic FFSC complex viz., F. fujikuroi, F. verticillioides, and F. proliferatum during storage of rice seeds with augemented antitoxin and seed invigorating potential. The novel SAS-Margosa composite was chemically and morphologically characterized using XRD, FTIR, TEM, and EDS analysis. The antifungal potential of margosa leaf extract adsorbed nanosilicate material (SAS) was examined using SEM, Flourescence microscopy and poison food technique. The toxin quantification of FFSC complex inoculated seeds treated with SAS-Margosa composite was carried out at monthly intervals upto a period of six months of storage along with control on two rice varieties viz., PR114 and Pusa Basmati 1121 respectively. The study revealed that SAS-Margosa composite coated seeds of PR114 and Pusa Basmati 1121 exhibited significanlty higher seed germination (87.63 & 83.57%) and minimum seed rot (5.70 & 5.24%) after 6 months of storage as compare to control. There was a significant decrease in levels of fusaric acid, fumonisins B1, B2 and gibberellic acid after six months as compare to control in both the varieties. The SAS-Margosa composite has been proved to be effective against toxigenic FFSC complex during rice seed storage without compromising the seed quality metrics.

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The neem [Azadirachta indica a: juss (meliaceae)] oil reduction in the in vitro production of zearalenone by Fusarium graminearum

Cited by 5 publications

References 19 publications

Biological Detail and Therapeutic Effect of Azadirachta Indica (Neem Tree) Products- A Review

Biological Detail and Therapeutic Effect of Azadirachta Indica (Neem Tree) Products- A Review

Neem Extract

Seed coating with novel sodium alumino silicate margosa composite – A proficient technique to reduce mycotoxins of Fusarium fujikuroi species complex inciting discoloration of rice

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