Rosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities

Abstract

The aim of this work was to investigate and compare the antiproliferative, antioxidant and antibacterial activities of Rosmarinus officinalis essential oil, native to Pakistan. The essential oil content from the leaves of R. officinalis was 0.93 g 100g -1 . The GC and GC-MS analysis revealed that the major components determined in R. officinalis essential oil were 1,8-cineol (38.5%), camphor (17.1%), -pinene (12.3%), limonene (6.23%), camphene (6.00%) and linalool (5.70%). The antiproliferative activity was tested against two cancer (MCF-7 and LNCaP) and one fibroblast cell line (NIH-3T3) using the MTT assay, while, the antioxidant activity was evaluated by the reduction of 2, 2-diphenyl-1-picryl hydrazyl (DPPH) and measuring percent inhibition of peroxidation in linoleic acid system. The disc diffusion and modified resazurin microtitre-plate assays were used to evaluate the inhibition zones (IZ) and minimum inhibitory concentration (MIC) of R. officinalis essential oil, respectively. It is concluded from the results that Rosmarinus officinalis essential oil exhibited antiproliferative, antioxidant and antibacterial activities.

Preservative effects of rosemary extract (Rosmarinus officinalis L.) on quality and storage stability of chicken meat patties

“…On general, there is no limitation on using the rosemary essential oil or their extract in meat products (Jordan Standards and Metrology Drganization, 2016). Rosemary oleoresin, extract, and their essential oils were reported as a potential antioxidant used widely in the food industry (Yu et al, 2002;Balentine et al, 2006;Hussain et al, 2010). On addition, it had been reported that rosemary extract (RE) was effective delaying lipid oxidation in meat (Georgantelis et al, 2007;Keokamnerd et al, 2008;Kahraman et al, 2015).…”

Evaluation of essential oils from 22 Guatemalan medicinal plants for in vitro activity against cancer and established cell lines

“…Oils from both of these plants are known to contain β-caryophyllene oxide, which has been noted for signal cascade inactivation resulting in down-regulation of proliferation and angiogenesis in some cancer cell lines (Park et al, 2011;Kim et al, 2014). Oils from R. officinalis also have been reported to have high inhibitory values against a variety of cell lines (Hussain et al, 2010;Wang et al, 2012).…”

ESTUDO COMPARATIVO DA ATIVIDADE ANTIBACTERIANA DE EXTRATOS VEGETAIS DE Senna spectabilis, Rosmarinus officinalis E Eugenia uniflora FRENTE À CEPA PADRÃO DE Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 6538 E Streptococcus pyogenes ATCC 19615

“…Estudo realizado por Hussain et al, (2010) o óleo essencial de alecrim possui boa atividade antimicrobiana sendo comparado ao controle ciprofloxacino. A atividade antimicrobiana do óleo essencial pode ser atribuída aos compostos α-pineno, cânfora, verbenona e borneol, sendo este o mais potente (SANTOYO et al, 2005 et al, (2005), extratos produzidos a partir de folhas desta planta demonstraram tal atividade contra S. mutans presentes na cavidade oral de humanos.…”