Evaluation of essential oils from 22 Guatemalan medicinal plants for in vitro activity against cancer and established cell lines

Miller, Andrew B.; Cates, Rex G.; O’Neill, Kim L.; Soria, Juan Alfonso Fuentes; Espinoza, Luis V; Alegre, Ballantines Fabrizio; Martínez, José Vicente; Arbizu, Dany Raul

doi:10.5897/jmpr2017.6528

Cited by 3 publications

(3 citation statements)

References 42 publications

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“…The EO (yield of 0.23% w/w) was extracted from the plant collected in Guatemala. The IC 50 values of the EO against AGS, A375, and A431 cell lines were 0.21, 0.24, and 0.41 μL/mL, respectively [22].…”

Section: Origanummentioning

confidence: 92%

“…The plant was collected in Guatemala, and the yield of EO was 0.66% w/w. The IC 50 values of the EO against epithelial gastric adenocarcinoma, epithelial malignant melanoma, and epithelial squamous carcinoma were 0.18, 0.09, and 0.08 μL/mL, respectively [22].…”

Section: Origanummentioning

confidence: 93%

“…The main components of the EO were methyl cinnamate (70.1%), linalool (17.5%), β-elemene (2.6%), and camphor (1.52%). The IC 50 values of the EO against AGS (epithelial gastric adenocarcinoma), A375 (epithelial malignant melanoma), and A431 (epithelial squamous carcinoma) cell lines were 0.39, 0.36, and 0.34 μL/mL, respectively [22].…”

Section: Ocimummentioning

confidence: 97%

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Cytotoxic Activity of Essential Oils of Some Species from Lamiaceae Family

Pérez-González¹,

Pérez‐Ramos²,

Méndez-Cuesta³

et al. 2019

Cytotoxicity - Definition, Identification, and Cytotoxic Compounds

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Cancer is considered one of the most lethal diseases in the world, with a prevalence of 439.2 cases and 163.5 deaths per 100,000 inhabitants, in the period from 2011 to 2015; this disease has a greater impact in underdeveloped countries. For the treatment of this disease, a combination of chemotherapy with surgery or radiation is generally used, however, it is not exempt from adverse effects or resistance of the tumor to this type of treatment, for this reason the search for new treatments is constant. The plants are a possible source to achieve this; Lamiaceae is a family of plants widely distributed on the planet and has been used traditionally for the treatment of different diseases, and various essential oils with the potential for cancer treatment have been isolated from this species. The scope of this review is to present 46 essential oils isolated from different species of Lamiaceae which have been tested against different cancer cell lines.

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Section: Origanummentioning

confidence: 92%

Section: Origanummentioning

confidence: 93%

See 1 more Smart Citation

Cytotoxic Activity of Essential Oils of Some Species from Lamiaceae Family

Pérez-González¹,

Pérez‐Ramos²,

Méndez-Cuesta³

et al. 2019

Cytotoxicity - Definition, Identification, and Cytotoxic Compounds

View full text Add to dashboard Cite

show abstract

The New World Bays (Litsea, Lauraceae). A Botanical, Chemical, Pharmacological and Ecological Review in Relation to their Traditional and Potential Applications as Phytomedicines

López-Caamal

Reyes-Chilpa

2021

Bot. Rev.

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Enhanced Natural Strength: Lamiaceae Essential Oils and Nanotechnology in In Vitro and In Vivo Medical Research

Kowalczyk,

Merecz-Sadowska,

Ghorbanpour

et al. 2023

IJMS

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The Lamiaceae is one of the most important families in the production of essential oils known to have a wide spectrum of biological activity. Recent research has highlighted the dermatological capabilities of various Lamiaceae essential oils, which appear to offer potential in free radical scavenging and anti-inflammatory activity. Some have also been extensively studied for their tissue remodeling and wound-healing, anti-aging, anti-melanogenic, and anti-cancer properties. Certain Lamiaceae essential oils are promising as novel therapeutic alternatives for skin disorders. This potential has seen substantial efforts dedicated to the development of modern formulations based on nanotechnology, enabling the topical application of various Lamiaceae essential oils. This review provides a comprehensive summary of the utilization of various essential oils from the Lamiaceae family over the past decade. It offers an overview of the current state of knowledge concerning the use of these oils as antioxidants, anti-inflammatory agents, wound-healers, anti-aging agents, anti-melanogenic agents, and anticancer agents, both alone and in combination with nanoparticles. Additionally, the review explores their potential applicability in patents regarding skin diseases.

show abstract

Evaluation of essential oils from 22 Guatemalan medicinal plants for in vitro activity against cancer and established cell lines

Cited by 3 publications

References 42 publications

Cytotoxic Activity of Essential Oils of Some Species from Lamiaceae Family

Cytotoxic Activity of Essential Oils of Some Species from Lamiaceae Family

The New World Bays (Litsea, Lauraceae). A Botanical, Chemical, Pharmacological and Ecological Review in Relation to their Traditional and Potential Applications as Phytomedicines

Enhanced Natural Strength: Lamiaceae Essential Oils and Nanotechnology in In Vitro and In Vivo Medical Research

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