Antimicrobial activity of Syzygium cumini (Myrtaceae) leaves extract

Oliveira, Guilherme Ferreira de; Araçari, Niege; Cardoso, J.L.; Silva, Ademar Alves da; Henrique, Carlos; Martins, Carlos Henrique Gomes; Bastos, Jairo Kenupp; Cunha, Wilson Roberto; Andrade, Márcio Luís de

doi:10.1590/s1517-83822007000200035

Cited by 70 publications

(54 citation statements)

References 17 publications

(13 reference statements)

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“…Leave extract from EJL has potential to scavenge nitric oxide (NO) and can be used to treat conditions with disproportionate production of NO [79]. Hydro-alcoholic extract of leaves from EJL is considered effective against multi-resistant strains of Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus and Candida krusei [80].…”

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confidence: 99%

Exploration of the in vitro cytotoxic and antiviral activities of different medicinal plants against infectious bursal disease (IBD) virus

et al. 2014

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Infectious bursal disease (IBD) caused by non-enveloped double stranded RNA virus is an acute and contagious poultry disease. Outbreak of IBD could result in 10-75% mortality of the birds; hence it has gained socio-economic importance worldwide. Medicinal plants have shown broad spectrum anti-viral activities against RNA and DNA viruses. Moringa oleifera Lam (MOL), Phyllanthus emblicus Linn (PEL), Glycyrrhiza glabra Linn (GGL), and Eugenia jambolana Lam (EJL) are commonly available medicinal plants of the sub-continent and exhibited anti-viral potential against different viruses. Ethanolic extracts of the leaves of MOL and EJL, roots of GGL and dried fruit of PEL were investigated for their cytotoxic and anti-viral potential against IBD virus using MTT colorimetric assay and anti-viral assay. Significant anti-viral potential (P<0.001) was demonstrated at concentrations 12.5, 25, 50 and 100 µg ml -1 of GGL, PEL, MOL and EJL, respectively, with no cytotoxicity. Data also spotlighted that all tested plant extracts possess significant anti-viral potential and this trend was higher in GGL followed by PEL, MOL, and EJL. The data undoubtedly conclude that these medicinal plants contain several health beneficial phyto-chemicals which got significant anti-viral potential and effectively be utilized against IBD virus. Moreover, the outcomes of this study provide a platform on the way to discover novel anti-viral agents against IBD virus and other viruses from plant origin.

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confidence: 99%

Exploration of the in vitro cytotoxic and antiviral activities of different medicinal plants against infectious bursal disease (IBD) virus

et al. 2014

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“…The use of medicinal plants plays an essential role in convening the main health needs in developing countries and these plants may offer a modern source of antibacterial, antifungal and antiviral agents with significant activity against infective microorganisms (Shadomy et al, 1985;Odds, 1989). Oliveira et al (2007) reported the antimicrobial activity of Syzygium cumini extract from leaves. Kumar and Vaidhyalingam (2010) reported the antibacterial and antifungal activity of Rubus racemosus extract from aerial parts.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical analysis and antimicrobial evaluation of Andrographis lineata Nees leaves and stem extracts

Alagesaboopathi¹

2011

Afr. J. Pharm. Pharmacol.

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The present investigation was designed to evaluate the antibacterial, antifungal properties and physiochemical screening of the various leaves and stem extracts of Andrographis lineata. Acetone, ethanol, methanol, petroleum ether and chloroform extracts of shade dried plant leaf and stem of A. lineata were tested for antibacterial, antifungal and phytochemical analysis. The antibacterial properties of various extracts of leaves and stem of A. lineata were assayed using the standard disc diffusion method, against five strains of bacterial species, namely, Proteus vulgaris, Escherichia coli, Klebsiela pneumoniae, Staphylococcus aureus and Pseudomonas aeruginosa. Among different solvent extracts studied, the methanol leaf extract showed highest antibacterial activity against staphylococcus aureus (19.41 mm); followed by petroleum ether extract (18.30 mm). The highest inhibition zone observed for acetone extract of A. lineata leaves against P. vulgaris was 17.40 mm followed by ethanol extract (16.10 mm). The highest activity of chloroform extract against K. pneumoniae was 14.07 mm. Phytochemical investigation confirmed the presence of flavonoids, saponins, gums and mucilages, triterpenoids, steroids, glycosides, phenolic compounds and tannins. The acetone leaf extracts of A. lineata showed highest antifungal activity against Penicillium pinophilum (13.40 mm). The methanol leaf extracts showed maximum activity against Aspergillus niger (12.15 mm). The petroleum ether leaf extracts showed highest activity against P. pinophilum (12.11 mm). The ethanol leaf extracts showed significant activity against Aspergillus flavus (11.24 mm). The chloroform leaf extracts showed higher activity against A. niger (9.75 mm). The leaf extract showed more inhibitory effect than the stem extracts. The present research justifies the claimed uses of this herb in the traditional system of medicine to treat different diseases.

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“…TLC analysis was done under UV light at wavelength of 254 nm or 366 nm. Then, plate was sprayed with a mixture containing 1% Ce(SO4) 2 and 10% H 2 SO 4 and heated for 5 minutes at 110°C. Once components of the fraction were successfully separated with good Rf value with appropriate eluent mixture, they were fractionated using column chromatography using solvent mixture n-hexane:EtOAc (50:1).…”

Section: Large Scale Bioproductionmentioning

confidence: 99%

“…Jamblang plant [1] was one of the many herbaceous plants where its exudate and parts of the plant (twigs and leaves) were regularly used for the treatment of diseases such as diarrhea and diabetes by the laymen in Indonesian society. Previous studies have documented that leaves of Jamblang plants were used for dental hygiene treatment (strengthening the gums and teeth) while the branches were useful as antimicrobial agent [2], antigenotoxic, antiulcerogenic, antiallergic, and hepatoprotective effect [3]. Furthermore, the extract of this plant contained tannins, essential oils, resins, glucoside, and gallic acid [4].…”

Section: Introductionmentioning

confidence: 99%

IDENTIFICATION AND CHARACTERIZATION OF POTENT ANTIMICROBIAL SECONDARY METABOLITE GENERATED FROM ENDOPHYTIC FUNGI ISOLATED FROM JAMBLANG PLANT ( Eugenia cumini L)

Kumala

Aprilia²,

Simanjuntak³

2017

Asian J Pharm Clin Res

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Objective: Colletotrichum capsici endophytic fungi were isolated from Jamblang plant (Eugenia cumini L.). The secondary metabolites of this plant have potent antibacterial efficacy as well as antidiarrheal and antidiabetic. This research focused on isolation of the endophytic microbes from branches of Jamblang plants and their secondary metabolites. Methods:Isolation of endophytes was performed in potato dextrose agar using direct seed plant. Endophytic fungi isolates with strongest antimicrobial activity against the bacteria Staphylococcus aureus and Escherichia coli were fermented in potato dextrose yeast to produce large scale of the metabolites. Supernatant was extracted with ethyl acetate (EtOAc) solvent. EtOAc extract fractionated by column chromatography (SiO 3 , n-hexane:EtOAc=50:1~1:1) and obtained three fractions. Further, agar diffusion method was performed to assess their antimicrobial activity.Results: Antibacterial test results indicated that fraction III had potent antibacterial activity S. aureus with inhibition zone diameter of 10.7 mm but no observed activity against E. coli. Furthermore, identification by gas chromatography-mass spectrometry showed that compounds present in fraction III were mainly fatty acid and phenolic compounds. Conclusion:Secondary metabolites isolated from Jamblang plants branches contained predominantly fatty acid and phenol-related compounds that could be responsible for its potent antimicrobial activity.

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Antimicrobial activity of Syzygium cumini (Myrtaceae) leaves extract

Cited by 70 publications

References 17 publications

Exploration of the in vitro cytotoxic and antiviral activities of different medicinal plants against infectious bursal disease (IBD) virus

Exploration of the in vitro cytotoxic and antiviral activities of different medicinal plants against infectious bursal disease (IBD) virus

Phytochemical analysis and antimicrobial evaluation of Andrographis lineata Nees leaves and stem extracts

IDENTIFICATION AND CHARACTERIZATION OF POTENT ANTIMICROBIAL SECONDARY METABOLITE GENERATED FROM ENDOPHYTIC FUNGI ISOLATED FROM JAMBLANG PLANT ( Eugenia cumini L)

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