Brucella spp. isolation from dogs from commercial breeding kennels in São Paulo state, Brazil

Keid, Lara Borges; Soares, Rodrigo Martins; Morais, Zenáide Maria de; Richtzenhain, Leonardo José; Vasconcellos, Sílvio Arruda

doi:10.1590/s1517-83822004000100027

Cited by 24 publications

(32 citation statements)

References 10 publications

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“…The infected female can produce consecutive abortions and present litters of sick-born pups that die a few hours to more than one month after delivery. Birth of apparently normal offspring who develop the disease later can occur [82][83][84][85][86][87]. Abortions, premature litters and conception failures are observed in infected kennels [81,88].…”

Section: Brucellosis In Dogsmentioning

confidence: 99%

Clinical Manifestations of Brucellosis in Domestic Animals and Humans

Megid¹,

Mathias²,

Robles³

2010

TOVSJ

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Brucellosis in domestic animals is a chronic disease that is characterized mainly by reproductive signs in cattle, buffaloes, pigs, sheep, goats and dogs. In females the disease is characterized by abortion, placenta retention, vaginal secretions, low fertility rate and also embryonic and neonatal death. In males, regular findings include epididymitis, orchitis, uni-or bilateral testicular atrophy, sperm abnormalities and infertility. Lymphadenopathy, hepatopathy, splenomegaly, uveitis and discospondylitis may also be observed in dogs. In horses, the typical clinical sign is characterized by a granulomatous supraspinous or supra-atlantal bursa lesion. Infected animals can also be asymptomatic. Infected symptomatic or asymptomatic animals represent an important source of infection to other animals and humans. Brucellosis in humans can cause undulant fever, malaise, insomnia, anorexia, headache, arthralgia, constipation, sexual impotence, nervousness and depression. For all species the presentation of clinical signs are only suggestive of disease infection and thus must be differentiated from other diseases.

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Section: Brucellosis In Dogsmentioning

confidence: 99%

Clinical Manifestations of Brucellosis in Domestic Animals and Humans

Megid¹,

Mathias²,

Robles³

2010

TOVSJ

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“…Canine brucellosis caused by Brucella canis is one of these factors and enlargement of lymph nodes, uveitis, osteomyelitis, polyarthritis, glomerulonephritis, pyogranulomatous dermatitis, epididymitis, orchitis, scrotal dermatitis (sometimes scrotal necrosis) are other clinical signs of this infection [3][4][5][6] . This letter is written to underline the possibility of canine brucellosis caused by other Brucella species, and to share an interesting case of dog brucellosis originated from ruminants with colleagues.…”

Section: Dear Editormentioning

confidence: 99%

Dejeneratif Diskospondilitis ve Koksafemoral Osteoartritisli bir Köpekte Gözden Kaçan Enfeksiyon: Ruminant Kökenli Brusellozis

Kuşçu¹,

Bedizci²,

Avki³

et al. 2014

Kafkas Univ Vet Fak Derg

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Dear Editor,Canine degenerative osteoarthritis and discospondylitis are serious disorders of locomotor system with many etiologic factors contributing to pathogenesis [1,2] . Canine brucellosis caused by Brucella canis is one of these factors and enlargement of lymph nodes, uveitis, osteomyelitis, polyarthritis, glomerulonephritis, pyogranulomatous dermatitis, epididymitis, orchitis, scrotal dermatitis (sometimes scrotal necrosis) are other clinical signs of this infection [3][4][5][6] . This letter is written to underline the possibility of canine brucellosis caused by other Brucella species, and to share an interesting case of dog brucellosis originated from ruminants with colleagues.A 4½ years old male Labrador dog was brought to the clinic with complaints of reluctance to walk; inability to jump into a car; growling when his back was touched and lethargy. As it was learned from the patient's story, the complaints were become apparent during past 6 months, but since two years he does not want to sit after walking due to swelling and pain in the testicles, and therefore he had been castrated. On physical examination, body temperature, pulse and respiratory rates were within normal values and pain was recorded on palpation of the left hip joint and lumbar region. When raised on hind legs, it was noted that he could not tolerate this position more than 30 seconds. Laboratory examination revealed that WBC count (19.57 x10 9 /L), % values of basophils and neutrophils were increased and % value of lymphocytes was decreased. Serum CRP level was quite high (119 mg/L). On radiographic examination, signs of degenerative osteoarthritis were observed in right hip joint (Fig. 1A and B) and lumbar-coccygeal vertebrae (Fig. 1C and D). A Brucella infection had aroused suspicion due to the orchitis and castration story. His serum sample gave negative result for Brucella canis with an immunochromatographic test kit (Brucella IC®, Biopronix, Agrolabo SpA, Italy), but it was positive with Rose Bengal plate test (SeroLam®, Seromed, Istanbul) which detects IgG and IgM formed against smooth Brucella species. According to the test results, dog was thought to be infected with one of these bacteria species: Brucella melitensis (sheep and goats), Brucella abortus (cattle) or Brucella suis (swine). While this development has been shared with the owner, it was learned that the dog had run around in neighboring goat farm since his puppyhood. Isolation of specific bacteria was not able because synovial fluid sampling of the relevant joints was not possible. Based on the serological tests results and owner's last information, the dog's disease was considered as ruminant originated brucellosis, and concerned pathologies (orchitis, diskospondylitis and degenerative right hip osteoarthritis) were thought to be related to this overlooked and chronic infection. Dog was treated for 2 months with doxycycline (2 times a day 300 mg, oral route, Monodoks® 100 mg capsules, Deva, Istanbul) and streptomycin sulfate (1 g IM and in 1, 3, 5 and 8 th weeks ...

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“…In the region of Botucatu in the state of São Paulo, the prevalence was 0.84% using population and diagnostic test similar to that used in the previous study . Keid et al (2004) studied the prevalence of brucellosis in 12 commercial kennels in São Paulo state, where the seroprevalence by AGID ranged from 40 to 77%. When blood culture analysis was used instead, the prevalence ranged from 2.7 to 54.54%.…”

Section: Vaginitis Caused By Brucella Canismentioning

confidence: 99%

Clinical approach to canine vaginitis

2012

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Vaginitis is a rare disease in adult female dogs. However, knowledge regarding this illness is important because, if secondary to reproductive tract anomalies that go uncorrected, it can cause ascending uterine infections and, consequently, subfertility or even infertility. Usually, these infections are caused by Enterobacter or microorganisms from the urogenital inferior system, such as Staphylococcus spp, Streptococcus spp, Escherichia coli, Proteus spp, Pseudomonas aeruginosa, Pasteurella, etc. In some cases, vaginitis may be caused by primary infections with Brucella canis, which is zoonotic, or by canine herpesvirus; both of these agents have the potential to cause reproductive failure. The disease can occur in any age, breed or ovarian condition and can be identified by vaginal cytology, vaginoscopy and culture of vaginal secretions. The most common clinical signs are erythema of the vaginal mucous, vaginal discharge, pollakiuria, licking of the vulva and attraction of male dogs, independent of the phase of the estrous cycle. This disease is generally self-limiting, and the treatment, when necessary, consists of antibiotic therapy, vaginal cleaning with antiseptic and, eventually, surgical correction of predisposing abnormalities. Key words: Inflammation/infection vaginal, reproduction, bitch ResumoA vaginite é uma afecção rara em cadelas adultas. É uma causa importante de subfertilidade ou infertilidade, quando secundária à anomalias do trato reprodutivo. Normalmente, são causadas por enterobactérias ou pela microbiota do sistema urogenital inferior, tais como Staphylococcus spp, Streptococcus spp, Escherichia coli, Proteus spp, Pseudomonas aeruginosa, Pasteurella, entre outras. Em alguns casos, pode ser primária como infecções por Brucella canis, a qual é uma zoonose ou herpesvírus canino, importante causa de falhas reprodutivas. A afecção acomete fêmeas de qualquer idade, raça ou condição ovariana. Os sinais clínicos envolvem mucosa vaginal hiperêmica, corrimento vulvar, polaquiúria, lambedura vulvar, e atração de machos independente da fase do ciclo estral. Pode ser diagnosticada por citologia vaginal, vaginoscopia e cultura da secreção. A enfermidade, muitas vezes, é autolimitante e o tratamento, quando necessário, é realizado com infusão vaginal de antissépticos ou antibióticos e, eventualmente, correção cirúrgica de anormalidades predisponentes. Palavras-chave: Inflamação/infecção vaginal, reprodução, cadela

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Brucella spp. isolation from dogs from commercial breeding kennels in São Paulo state, Brazil

Cited by 24 publications

References 10 publications

Clinical Manifestations of Brucellosis in Domestic Animals and Humans

Clinical Manifestations of Brucellosis in Domestic Animals and Humans

Dejeneratif Diskospondilitis ve Koksafemoral Osteoartritisli bir Köpekte Gözden Kaçan Enfeksiyon: Ruminant Kökenli Brusellozis

Clinical approach to canine vaginitis

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