Oral manifestations in children with AIDS and in controls

Abstract

Thirty children with AIDS, aging 2 to 6 years, of both genders, treated as outpatients at the hospital Santa Casa de Misericórdia, São Paulo, were evaluated for oral manifestations and compared to a control group of age- and sex-matched healthy subjects. The correlation between oral lesions and the degree of immunosuppression was analyzed. The most prevalent oral manifestations--lymphadenopathy, followed by gingival alterations--were observed in the children with the highest levels of immunosuppression. Other manifestations observed in the AIDS group were: pseudomembranous and erythematous candidosis, enlargement of the parotids and ulcers. The results did not indicate a higher frequency of lesions. However, the observed oral manifestations had an early occurrence, which indicates that the early diagnosis is an important component in the management of those patients.

Patología oral en niños y adolescentes con VIH en tratamiento antirretroviral de gran actividad

“…En este estudio, el factor relacionado con la elevada prevalencia de gingivitis fue la inadecuada higiene oral ya que todos los pacientes recibían tratamiento antirretroviral de gran actividad. El hallazgo supera lo reportado por Flanagan et al, 21 con una prevalencia alta de gingivitis en un 50 % (19/38) de su población, Chen et al 23 informaron un 54 % (56/104), Bosco et al 15 manifestaron un 33,33 % (10/30) y Okunseri et al 16 reportaron un 20,6 % (21/102).…”

“…De igual manera Bosco et al 15 reportaron que las manifestaciones orofaciales son más frecuentes en niños con inmunosupresión moderada y severa, Benito et al 20 mencionaron que las patologías bucales están relacionadas con una mayor depresión del sistema inmunitario, Okunseri et al 16 reportaron además que los niños con bajo porcentaje de CD4 tuvieron más lesiones orales.…”

“…14 , Bosco et al 15 , Okunseri et al 16 , Pongsiriwet et al 17 y Miziara et al 18 concluyen que el uso de TARGA produce una gran disminución de las patologías orales asociadas al VIH. Mientras que Ferreira et al 19 y Benito et al 20 reportan una ligera reducción de estas patologías.…”

Rinossinusites em crianças infectadas pelo HIV sob terapia anti-retroviral

“…4,5 Its pre- Table 5. Serum CD4+ T lymphocyte counts according to the presence of rhinosinusitis in children aged from 6 to 12 years and 11 months.…”

“…3,4 This disease, together with the fact that many of the initial signs and symptoms of HIV infection occur in the ear, nose and throat, has meant that many such patients are brought in for assessment by otorhinolaryngolotists. 3,5,6 Children generally present six to eight upper respiratory virus infections a year. 7 About 5% to 13% of these episodes progress to secondary bacterial rhinosinusitis.…”