Profile of susceptibility in vitro of Trichosporon asahii and Trichosporon inkin strains against cyclic imides

Abstract

In vitro susceptibility testing of Trichosporon asahii (13 strains) and T. inkin (13 strains) against cyclic imides (succinimides, naphtalimides and maleimides) in concentrations of 200 to 6,25 μg/mL was performed according to the diffusion agar method. By the results obtained, the antifungal activity of the cyclic imides: 3,4-dichloro-N-phenyl-maleimide; 3,4-dichloro-N-phenyl-ethylmaleimide and 3,4-dichloro-N-phenyl-propyl-maleimide (50 μg/ mL) over T. asahii and T. inkin was important and it may be helpful in showing perspectives in a search for new antimicotic products.