Application of the laser radiation in patients of pressure ulcers: clinical and histomorphometric analysis of the derm

Rocha, José Carlos Tatmatsu; Catanho, Maria Tereza Jansem de Almeida; Mota, Diógenes Luís da

doi:10.1590/s1516-89132008000700038

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Vale salientar que, de acordo com Marcom e André, 17 as exposições radiantes para o tratamento de feridas situam-se numa faixa que varia aproximadamente entre 1 e 9 J/cm 2 . No entanto, para Abrahão et al 16 e para Rocha et al 18 não existe ainda um consenso no que diz respeito aos parâmetros da irradiação e qual o melhor tipo de laser utilizado no tratamento de feridas crônicas, mas normalmente encontra-se na literatura que o uso clínico dos lasers de HeNe e de AsGa para incremento da circulação no local da ferida deve variar entre 1 a 5J/cm 2 . Neste estudo, utilizaram-se os lasers HeNe e AsGa com dose de 5 J/cm 2 , corroborando esses achados.…”

Section: Discussionunclassified

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Effects of Helium-Neon (HeNe) and Gallium Arsenide (GaAs) lasers associated with prevention guidelines and treatment of pressure ulcers

Fialho¹,

Baron²,

Brandenburg³

et al. 2017

Revista Médica De Minas Gerais

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Section: Discussionunclassified

“…Neste estudo, foi necessário um número maior de sessões, ou seja, 52, 22 e 46, respectivamente, nos três casos. Rocha et al 18 descrevem ainda a boa evolução clínica de 12 pacientes com úlceras por pressão tratadas com AsGa.…”

Section: Discussionunclassified

Effects of Helium-Neon (HeNe) and Gallium Arsenide (GaAs) lasers associated with prevention guidelines and treatment of pressure ulcers

Fialho¹,

Baron²,

Brandenburg³

et al. 2017

Revista Médica De Minas Gerais

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Low-level laser therapy (904nm) can increase collagen and reduce oxidative and nitrosative stress in diabetic wounded mouse skin

Tatmatsu-Rocha

Ferraresi

Hamblin

et al. 2016

Journal of Photochemistry and Photobiology B: Biology

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Background and Objective Over the last decade we have seen an increased interest in the use of Low-Level Laser Therapy (LLLT) in diseases that involve increased oxidative stress. It is well established that hyperglycemia in diabetes elicits a rise in reactive oxygen species (ROS) production but the effect of LLLT remains unclear. This study aimed to investigate whether LLLT was able to improve oxidative/nitrosative stress parameters in the wound healing process in diabetic mice. Study Design/Materials and Methods Twenty male mice were divided into four groups: non-irradiated control (NIC), irradiated control (IC), non-irradiated and diabetic (NID), irradiated and diabetic (ID). Diabetes was induced by administration of streptozotocin. Wounds were created 120 days after the induction of diabetes in groups IC and ID and these groups were irradiated daily for 5 days (superpulsed 904 nm laser, average power 40 mW, 60 sec). All animals were sacrificed 1 day after the last irradiation and histology, collagen amount, catalase activity, nitrite and thiobarbituric acid reactive substances (TBARS) were measured. Results Histology showed that collagen fibers were more organized in IC and ID when compared to NID group, and significant differences in collagen content were found in group ID versus NID. Catalase activity was higher in IC group compared to other groups (p < 0.001). TBARS levels were higher in IC versus NIC, but were lower in ID versus NID (p < 0.001). Nitrite was lower in both irradiated groups versus the respective non-irradiated groups (p < 0.001). Conclusions Delayed wound healing in diabetes is still a challenge in clinical practice with high social costs. The increased production of collagen and decreased oxidative and nitrosative stress suggests that LLLT may be a viable therapeutic alternative in diabetic wound healing.

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Application of the laser radiation in patients of pressure ulcers: clinical and histomorphometric analysis of the derm

Abstract: In this work, we analyze the clinical alterations and histological modifications in patients with

Cited by 2 publications

References 7 publications

Effects of Helium-Neon (HeNe) and Gallium Arsenide (GaAs) lasers associated with prevention guidelines and treatment of pressure ulcers

Effects of Helium-Neon (HeNe) and Gallium Arsenide (GaAs) lasers associated with prevention guidelines and treatment of pressure ulcers

Low-level laser therapy (904nm) can increase collagen and reduce oxidative and nitrosative stress in diabetic wounded mouse skin

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